#hypp

[craigslisthorses]

Another diseased quarter horse for your viewing

[craigslisthorses]

This N/H mare on facebook the owner is saying "will be a great broodmare"

[craigslisthorses]

Hyperkalemic Periodic Paralysis (HYPP)

Breeds with HYPP; Quarter Horses, American Paint Horses, Appaloosas, and Quarter Horse Crosses.

HYPP

"An inherited disease of the muscle, caused by a genetic defect. A mutation in the sodium channel gene. Sodium channels are pores in the muscle cell membrane which control contraction of the muscle fibers. When the defective sodium channel gene is present, the channel becomes “leaky” and makes the muscle overly excitable and contract involuntarily. The channel become “leaky” when potassium levels fluctuate in the blood. This may occur with fasting followed by consumption of a high potassium feed such as alfalfa. Hyperkalemia, which is an excessive amount of potassium in the blood, causes the muscles in the horse to contract more readily than normal. This makes the horse susceptible to sporadic episodes of muscle tremors or paralysis."

GENOTYPE

HYPP Positive= H/N and H/H

HYPP Negative= HYPP N/N

HYPP horses with H/N genotype means they are heterozygous carriers, carrying one copy of the HYPP gene. If you bred a mare who is H/N to a stallion who is N/N, you would have about a 50% chance the foal is H/N as well. However if you bred an H/N mare to an H/N stallion you will have about a 25% chance the foal being N/N, a 50% chance it will be H/N, and a 25% chance it will be H/H.

HYPP horses with the H/H genotype means it is homozygous, carrying both copies of the HYPP gene. 100% passing the HYPP gene to it's offspring.

I made a thing in case it helps the visual learners out there

IMPRESSIVE (but not really)

Let's talk about the QH stallion, Impressive. All horses that have a HYPP positive gene of any kind, all descend from this horse. Impressive sired 2,250 foals and they estimate he has around 50,000 living descendants. No dilution of lineage will remove HYPP, as it is a dominant trait and will show whether you are 5 generations back or 2.

HYPP SYMPTOMS

HYPP varies in severity, it's not always equal and every horse may have different reactions. HYPP can be confused for tying-up or even colic, they may have difficulty breathing, muscle tremors, sweating, weakness, tremors. In more severe cases the horse may collapse from paralysis of the muscles in the airway and can result in sudden death.

Not every horse who is HYPP positive may display symptoms, making this disease sometimes hard to detect.

IS IT CURABLE?

No. HYPP may be managed with diet and certain medicines for maintenance but it cannot be cured. H/H positive horses have poor prognosis and can be much more difficult to manage.

VIDEOS OF HYPP ATTACKS

CW: Horses in distress, videos may be hard to watch for some.

Video 1

Video 2

Video 3

Video 4

Video 5

Sources (and if you want to read more); AAEP , UCDavis, Tri-State

Is there anything I forgot? Anything to add? Just covering the basics of this disease and what it does to these horses.

[potterkanae]

たくさんの子供達、ものづくりを楽しむ大人達に、これからももっとも～っと陶芸を教えて行きたいな~想像力豊かになって欲しいな✨ 生活苦様式が変化してきて、なおさらに強く思っている事。 今日はとても心に響くセミナーに参加して❗️漠然としていた何かを再確認出来ました✨😃素晴らしい講師の先生でした。 #hypp #想像力を育む #陶芸好きと繋がりたい #広島 #陶芸 #nhk文化センター広島 #コロナ対策してます #pottery #陶芸家 #陶芸体験#ものづくり#potterkanae #POTTER華苗 陶工房＆GALLERY #陶芸教室 #器 #世界にひとつ #じゃらん遊び体験 (Potter華苗) https://www.instagram.com/p/CikOHq1v6rd/?igshid=NGJjMDIxMWI=

[craigslisthorses]

and they wonder why so many horses are affected with genetic life threatening diseases. 

[equestrinope-archive]

I wanted it to be so much more, but time constraints and damaged files killed me. Either way, I think it’s informational! @horsblr @muscle-horse-appreciation

Again, the purpose of this project was not to dump on HYPP positive horses, but bring awareness to the illness. Keep loving your HYPP horses, but please don’t breed them! 

[xlost-inlovex-blog]

Take me away love

[eventing-dreams]

I’m doing a paper for my bio class and my question is- does anyone have any articles I can read on HYPP?