#immune responses

[intelligentliving]

Long-Term Opioid Users Develop Antibodies Against The Drugs

New research of opioid antibodies produced by the immune systems of long-term opioid users was recently presented at the Fall 2020 virtual meeting of the American Chemical Society. The researchers who presented the discovery suggest that these antibodies could be responsible for some of the adverse side effects seen in...

[oaresearchpaper]

An ongoing novel highly contagious pneumonia outbreak started in Wuhan, which is the sprawling capital of central china’s province, Hubei, in late December 2019. The disease was officially named by the World Health Organization on February 12, 2020, as Coronavirus Disease 2019 (COVID-19) was caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The primary host of SARS-CoV-2 is linked with bat species however; the intermediate host is still not clear. The COVID-19 spread rapidly across the world because of person-person transmission. The SARS-CoV-2 stimulates both the cellular and humoral immunity mediated by viral-specific B and T cells. Cases of COVID-19 infection exhibit several clinical complications for example fever, tiredness and dry cough. Diagnosis is mostly depending on epidemiological characteristics, clinical manifestation, and few through the examination of auxiliary tissues. In this review, we have provided a brief introduction of SARS-CoV-2, pathogenesis, diagnosis, immune responses, and treatments and future perspectives.

[sommesick]

Cytokines are a broad class of small, secreted proteins that act locally or systemically by binding to cognate receptors on target cells, which in turn trigger downstream signalling and orchestrate activities among cell types of the immune system.

Cytokine-based therapies and cytokine antagonists are used to treat a wide range of disorders, including cancer and autoimmunity.

However, the large number of immune cell types and cytokines and complex cellular responses have made it challenging to elucidate in vivo immune responses to cytokines. 

Dictionary of immune responses to cytokines at single-cell resolution - Nature

An extensive global transcriptomics analysis of in vivo responses to 86 cytokines across more than 17 immune cell types reveals enormous com

[jhponestop]

Potatoes Good for Heart Health; know the Reasons why

Potatoes Good for Heart Health; know the Reasons why

Potatoes have always been the food surrounded by many misconceptions. Whether it is the talk about how potatoes make us gain weight or how they are bad for a heart patient. Well, let’s debunk the myth and know why potatoes are great for heart patients. Any vegetable, if eaten, after frying is unhealthy for you and the same goes for potatoes. But boiled potatoes, mashed potatoes, and baked…

View On WordPress

[jhponestop]

With COVID Aid, Schools try Something New - Giving Students Jobs

With COVID Aid, Schools try Something New – Giving Students Jobs

Kelly King was able to do something this summer she’d never been able to before: pay students to help others. King, who works for the school district on Alaska’s Kenai Peninsula, used federal COVID aid to hire three rising high school seniors to staff a booth at a riverside park. There, as crowds flocked to a farmers market and free concerts, the students told residents how local schools could…

View On WordPress

[jhponestop]

Cancer patients may be at greater risk of death from COVID-19

Cancer patients may be at greater risk of death from COVID-19

New research confirms that COVID-19 can be life-threatening for certain cancer patients: More than 16,500 Americans with cancer died from complications related to coronavirus infection during the first 10 months of the pandemic. “People with cancer, especially blood cancers, who may be immunocompromised, and prostate cancer, who tend to be older, may be at greater risk of COVID-19 complications…

View On WordPress

[jhponestop]

Rethinking Immune Responses Involved in Skin Hypersensitivity

A study by immunologists at the University of Copenhagen has revealed a never-before-seen immune pathway involved in contact dermatitis – an allergic condition where individuals affected break out in rashes when they touch materials they are sensitive to. These allergens could be anything from metals used in jewelry to dyes, perfumes, and chemicals in cosmetics. Our current understanding of…

View On WordPress

[jhponestop]

New insights into Immune responses to Malaria

New insights into Immune responses to Malaria

Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically. An international team used mass cytometry—an in-depth way of characterizing individual cells—and machine learning to discover ‘immune signatures’ associated with symptomatic or…

View On WordPress