In the late 1990s and early 2000s, the pharmaceutical company, Wyeth, maker of hormone replacement therapies (HRTs) among other drugs, was facing competition as well as an increasing skepticism of HRTs benefits. Wyeth turned to "medical communication companies” like DesignWrite to create a series of articles and conference presentations that would expand the HRT market and provide reassurance to women and their doctors. Over almost a decade, DesignWrite produced over 50 peer-reviewed publications, scientific abstracts and posters, journal supplements, and symposia for Wyeth, all supposedly authored and led by physicians in the field. This document and over a thousand more were produced during the lawsuit PREMPRO PRODUCTS LIABILITY LITIGATION, MDL DOCKET NO. 4:03CV1507 WRW (W.D. Arkansas) and made available to the public by a United States Federal judge in response to a request by PloS Medicine and The New York Times in 2009.