#laboratory animals

[yourapple56-blog]

Chimps from the lab go outdoors for the first time!

[barcforlife]

Black Animal/Beagle Rescue Coalition

aka BARC

[closet-keys]

From Gender: Animals

[hagleyvault]

Today’s #FashionFriday doubles as a #ScienceFriday, as this ca. 1950s photograph documents the DuPont Company’s human trials of experimental nylon fibers.

Nylon, a generic designation for a range of synthetic polymer fabrics, was commercially introduced by the DuPont Company on October 27, 1938. This announcement followed years of research into polymer fabrics that first began in 1927, when the company made the decision to split its chemical department into a collection of small research teams, each tasked with conducting research into practical applications for scientific discoveries and specific market goals.

Even after the introduction of nylon, DuPont continued to experiment with various polymer blends intended to make the fabric more comfortable and more durable. One particular issue raised by the new product was the question of dermatitis. New variants of nylon that emerged from DuPont’s labs during these decades were first tested on animals. If the product passed that test, it was then moved on to testing on paid human volunteers.

In this photo, small patches of nylon are being taped to women’s legs and arms at the Haskell Laboratory for Toxicology and Industrial Medicine near Newark, Delaware. The patches were left on for one week, then removed for ten days and again applied.

This photograph is part of the Hagley Library’s collection of DuPont Company Product Information photographs (Accession 1972.341). You can view more material from this collection online now by clicking here to view its page in our Digital Archive.

[rjzimmerman]

36 Beagles Saved as Controversial Pesticide Test Halted

A pesticide test that would have resulted in the deaths of 36 beagles has been stopped, HSUS and the company behind the test announced Monday.

I posted the original story a few days ago, which told us that the company would not halt the euthanasia because of the failure of some dumb ass bureaucrat at Dow DuPont Chemical to understand the rules of the game. Sometimes, we can be driven to insanity by dumb fuck desk sitters. “We have to kill the dogs.” “Why?” “Because nobody told me we don’t have to kill the dogs. Ask the people in Brazil.” “Why?” “I don’t know, that’s what my boss said.”

Excerpt from this EcoWatch article:

A controversial pesticide test that would have resulted in the deaths of 36 beagles has been stopped, the Humane Society of the United States (HSUS) and the company behind the test announced Monday. The announcement comes less than a week after HSUS made the test public when it released the results of an investigation into animal testing at Charles River Laboratories in Michigan.

"We have immediately ended the study that was the subject of attention last week and will make every effort to rehome the animals that were part of the study," Corteva Agriscience, the agriculture division of DowDupont, said in a statement announcing its decision.

Corteva had been testing a new fungicide called Adavelt®, which was being force-fed to the beagles in gelatin capsules for a year. In July 2019, the dogs would have been euthanized to assess the effects of the fungicide. Corteva had been conducting the test because it was technically required by Brazil's Agência Nacional de Vigilância Sanitária (ANVISA). The company and the Humane Society had been working with ANVISA to waive the requirement, and Corteva said it had finally received confirmation Monday from ANVISA that it did not need to proceed with the test, which it immediately halted.

"We applaud Dow AgroSciences (Corteva AgriScience) for making the right decision by ending the one-year pesticide test on 36 beagles at Charles River Laboratories in Michigan," HSUS President and CEO Kitty Block told the Detroit Free Press. "This is a significant step that is critical to the welfare of the dogs."

[drferox]

Hello Dr. Ferox, I have a small question -no rush to answer it though, it's pure curiosity-. I know someone who works with lab mice, and once jokingly said that the animal we know best is not humans -as we would be tempted to believe- but lab mice. So, I was wondering : has all that research led to new & better treatments for sick mice (or any other species used for experimentation)?

Unfortunately it hasn’t.

Partly the reason is that the number one diagnostic tool used to identify disease in laboratory animals is a post mortem examination. So the individual sick animal ends up dead, providing knowledge about the rest of the critters it was housed with. So any laboratory species medicine is geared towards prevention in the group rather than cure of the individual.

However, it does give us a wealth of information about drug dosages and toxicity studies. That allows exotic clinicians a degree of confidence is prescribing medication off-label, because we know the data for that drug, even if pharmaceutical companies have not bothered going through the registration process for that medication for a specific purpose in mice and rats.

Getting doses formulated that small can be another challenge entirely.

[vegan-childrens-stories]

Vegan graphic novel - Strange New World

Story continues from yesterday: * * * This story is fiction but the conditions described inside the laboratory breeding facility are informed by a former worker’s account. To find out more about the reality of these places and how you can help laboratory animals, go to the story page and scroll to the bottom. Thank you 🙂 Violet’s Vegan Comics – creating engrossing and enlightening…

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[vegan-childrens-stories]

Vegan graphic novel - Impenetrable

Story continues from yesterday: * * * Story continues tomorrow, or if you don’t want to wait you can read it now 🙂 Violet’s Vegan Comics – creating engrossing and enlightening vegan-friendly stories since 2012

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