Nerves, with their far-reaching signal-conducting projections called axons, are known to infiltrate and influence tumours – regulating their growth and metastatic behaviour. But the fine details remain poorly understood. This study describes a microfluidic device called DACIT (Device for Axon-Cancer cell Interaction Testing) that makes direct analysis of interactions between cancer cells and axons (in 2D and 3D) possible in the lab (mouse mammary cancer cells are shown in magenta interacting with nerve axons in yellow).
Read the published research article here
Image from work by Ines Velazquez-Quesada and colleagues
Bioengineering Department, Temple University, Philadelphia, PA, USA
Image originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 4.0)
Published in iScience, February 2026
You can also follow BPoD on Instagram, Twitter, Facebook and Bluesky