The result is that we reexperience the trauma that caused the pain and this trauma is continuously reinforced by it. The terror demoralizes us, and as pain-processing areas expand in the brain, we lose our full ability to problem-solve, regulate emotions, resolve conflicts, relate to others, distinguish other sensations from pain, effectively plan, and even remember how to apply our past experience to control pain. Every time the pain worsens, it feels like it is here to stay, and we must avoid it at all costs. The amygdala is not a place of moderation. It is a place of extreme emotions, fight-and-flight and post-traumatic stress disorder. Persistent pain demoralizes most people who have it.
Norman Doidge MD in “The Brain's Way of Healing: REMARKABLE DISCOVERIES and RECOVERIES from the FRONTIERS of NEUROPLASTICITY.”