Jan 8
Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex - Research
This study reveals how KICSTOR and GATOR1 assemble into a crescent-shaped lysosomal complex that regulates mTORC1 during amino acid starvation and how SAMTOR binds KICSTOR in an S-adenosylmethionine-incompatible conformation to couple methionine sensing to mTORC1 regulation. Read more about this post… Credits: Source Disclaimer