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The rising incidence of anthelmintic resistance in chicken parasites has necessitated the urgent development of sustainable, environmentally acceptable alternatives to traditional synthetic medications. Ethnoveterinary medicine presents a viable approach by employing bioactive plant extracts that proficiently control helminth infections while reducing chemical residues. This study assessed the in vitro anthelmintic efficacy of Betel Leaf (Piper betle) Ethanolic Extract (BLEE) against Ascaridia galli to combat the rising anthelmintic resistance in chicken. Adult nematodes were subjected to a completely randomized design (CRD), with exposure to BLEE doses of 40, 80, and 120 mg/ml, alongside a Levamisole control. The results indicated a substantial response that was dependent on both dosage and duration. At 2 hours, 120 mg/ml BLEE resulted in 83.33% mortality, demonstrating no significant difference from Levamisole. After 6 hours, all BLEE treatments had cumulative fatality rates ranging from 90.00% to 96.67%. Phytochemical analysis revealed that tannins and saponins are the principal bioactive chemicals responsible for inducing parasite paralysis. The research suggests that P. betle extract at 120 mg/ml serves as a powerful botanical substitute for synthetic anthelmintics, endorsing its incorporation into sustainable poultry health management practices.
Banana is a very delicious and nutritious fruit, economically more affordable in all over the world for all age groups from the Musaceae family. It belongs to the genus Musa. Banana is easily digestible, have low fat, sufficient amount of minerals and vitamins therefore used in special diets as for babies, patient having stomach disorders, arthritis. Every part of banana plant has specific health benefits, used to treat and prevent different diseases like cancer, ulcer, Alzheimer’s disease, infection, diarrhea, hemorrhoids, diabetes, and hypertension due to its antifungal, antibiotic, antimicrobial, antidiabetic, antioxidant, and anti-inflammatory properties. The unripe banana cooked form called plantains used as vegetable in some countries, useful for ulcer and digestive disorder. The leaves of banana plant are used for skin allergies, skin burns and flower of banana for bronchitis, diabetes, insect’s bites. The peel and pulp have dopamine, norepinephrine, serotonin which is effective for the smoothness of muscles of intestine and vitamin c of banana peel helps to get rid from free radical and protect the body from disease attack. The purpose of writing this review article to study the benefits of nutrients present in banana like phenols, flavonoids, phytochemicals, potassium, vitamins, fiber on human health.
A traditional medicinal plant which is native to tropical, subtropical and warm temperate areas of the globe. The plant is distributed as a contaminant in rice seed in France and Philippines. Running water especially floods distributes the seeds from field to field. The plant is common for its medicinal value in alternative systems of holistic health (Ayurvedic, Unani, Homeopathy, Sidha and Chinese) and herbal medicines. Scientific evidence for the folklore claim of the plant has been investigated in many studies but a summary of the data is not available. Detailed literature review of the plant with the recent advancement in research along with therapeutic potentials and scientific evidence are given herein. Databases such as Google Scholar, Elsevier, Science Direct and PubMed have been used to access the literature, thus excluding articles related to ecology, agriculture and synthetic work. The review indicated new potentials for the plant and revealed pharmacological activities supporting the traditional claim. For example, antitumor activity studies of the plant revealed its use for treating tumors. Moreover, clinical studies of the plant extract are mandatory based on safety, efficacy and pharmacokinetic data. The current review may be helpful for researchers intending to extend the research on the plant as well as in the preparation of evidence-based formulations in the pharmaceutical industry.
Pistacia integrrima is a typical therapeutic plant belongs to family Anacardiaceae and local to Japan, China and found in the Northern regions of Pakistan commonly called KakrraSingi (Urdu) and Shanai (Pushto). It is used ethnomedicinally for a number of diseases include fever, cough, asthma, vomiting, Ascaris, Anorexia, Allergy, viral infections, diarrhea, snake and scorpion biting sting. The different parts of the plant roots, leaves, stems, barks, Galls and fruits contains various bioactive compounds like amino acid, alkaloids, sterols, flavonoids, tannins, saponins, aromadendrene, Pistacinin, Pistacin, Dihydromalvic acid, Pistacienoic acid, sitosterol, resin, essential oils, caprylic acid, camphene, cineol, sterals, dihydroqueretin and triterpenoids. Antimicrobial activity of chloroform and ethanol leaves extract from Pistacia integrrima reported in many research papers. The leave extract exhibited the fungi growth including Aspergillus flavus, Dreschlera turcica and Fusarium verticillioides. The plant is known to have many biological activities including antibacterial, antifungal, analgesic, antioxidant, phytotoxic, cytotoxicity and antiasthmatic. The current review will cover biological activities, phytochemical evaluation, ethnomedicinal uses, ethnobotanical uses and aim to serve as a base for additional investigation and exploitation. The current review shows a gap needed further investigations and isolations of new compound, and its biological activities.
A traditional medicinal plant which is native to tropical, subtropical and warm temperate areas of the globe. The plant is distributed as a contaminant in rice seed in France and Philippines. Running water especially floods distributes the seeds from field to field. The plant is common for its medicinal value in alternative systems of holistic health (Ayurvedic, Unani, Homeopathy, Sidha and Chinese) and herbal medicines. Scientific evidence for the folklore claim of the plant has been investigated in many studies but a summary of the data is not available. Detailed literature review of the plant with the recent advancement in research along with therapeutic potentials and scientific evidence are given herein. Databases such as Google Scholar, Elsevier, Science Direct and PubMed have been used to access the literature, thus excluding articles related to ecology, agriculture and synthetic work. The review indicated new potentials for the plant and revealed pharmacological activities supporting the traditional claim. For example, antitumor activity studies of the plant revealed its use for treating tumors. Moreover, clinical studies of the plant extract are mandatory based on safety, efficacy and pharmacokinetic data. The current review may be helpful for researchers intending to extend the research on the plant as well as in the preparation of evidence-based formulations in the pharmaceutical industry.
Limited substantiations are available supporting the pharmacological properties of herbal plants utilized in ethno-veterinary medication which remained sustainable in local communities in spite of advancements in animal health today. This study evaluated through in vitro and in vivo anthelmintic assays the folkloric use of Chrysophyllum cainito and Psidium guajava, which are among the selection of documented florae in the Philippines being used in ethno-veterinary medicine. In vitro anthelmintic evaluation showed time-dependent and concentration-dependent efficacies. The ovicidal action of Chrysophyllum cainito bark ethanolic extract at 60mg/ml has recorded 94.65% inhibition capacity, whereas Psidium guajava bark ethanolic extract generated 92.64% and 96.28% efficacies at 30mg/ml and 60mg/ml dilutions, respectively. The wormicidal activity of the former elicited 88.88% at 60mg/kg, while the latter yielded 88.88% and 94.44% mortalities to worms at 30mg/ml and 60mg/ml dilutions, correspondingly. Probit analysis on the lethal concentration (LC50) against eggs and worms was logged at different magnitudes for both plants. In vivo assessment by means of fecal egg count reduction (FECR) rate has signified biologically, that the tested plants undoubtedly possess anthelmintic property.
The main objective of this work was to explore Punica granatum phytochemicaly and synthesize nanoparticles from its polar extract. The phytochemical screening test of ethanolic and aqueous extract of P. granatum indicated the presence of tannins, flavonoides, emodins, terpenoids, cardiac glycosides, coumarine, and soluble starch. The aqueous extract showed the presence of tannins, flavonoides, terpenoids, emodins, cardiac glycosides, caumarine, carbohydrates and soluble starch. The extracts were subjected to synthesize gold nanoparticles (Au-NPs) Synthesized Au-NPs were characterized by using Uv-visible, Fourier transform (FT-IR) spectroscopy and AFM (atomic force microscope) analysis. The active phytochemical present in extract are responsible for synthesizes gold nanoparticles (Au-NPs). In addition, synthesized Au-NPs and the methanolic extracts of Punica granatum were screened for their in-vitro antioxidant activity. Au-NPs showed excellent antioxidant potentials. It is concluded that Punica granatum extracts is an outstanding bioreducant for the rapid and green synthesis of Au-NPs, which in turn showed various antioxidant activity.