Oct 4, 2021
NCBI Gene 12
Symbol: SERPINA3
Full Name: serpin family A member 3
Type: Protein Coding
RefSeq Status: Reviewed, Experimental evidence at the protein level
Organism: Homo sapiens, chromosome 14
Description: Serpin family A member 3 is from the serpin family, which inhibit serine proteases. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Subcellular Location: Secreted
Sources: NCBI; UniProt