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Sugammadex Market Size, Share & Trends Analysis Report By Product Type: (For rocuronium and vecuronium, For rocuronium only) By Applications
NEW PATENT, SUGAMMADEX, WO 2016194001
NEW PATENT, SUGAMMADEX, WO 2016194001
NEW PATENT, SUGAMMADEX, WO 2016194001 WO2016194001, PROCESSES FOR PREPARATION OF SUGAMMADEX AND INTERMEDIATES THEREOF ALAPARTHI, Lakshmi Prasad; (IN). PAL, Palash; (IN). GINJUPALLI, Sadasiva Rao; (IN). SHARMA, Uday; (IN). CHOWDARY, Talluri Bhushaiah; (IN). MANTRI, Anand Vijaykumar; (IN). GADE, Bharath Reddy; (IN). KULKARNI, Gaurav; (IN) LINK…
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Read the full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49662 DOI: 10.4236/ojanes.2014.49029 Author(s) Eduardo Fernandes Orioli Guimarães, Muriel Mofreita Saldanha, Tiago Coelho Fortes, Marcelo Grisolia, Marcos Lopes de Miranda, Carlos Darcy Alves Bersot Affiliation(s) Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. ABSTRACT In rare cases, rocuronium has been associated with dose-related tachycardia, probably by a cardiac muscarinic M2 receptor blockade mechanism. We report the case of a 30-year-old female who underwent excision of a branchial cyst under general anesthesia. This patient presented an episode of sinus tachycardia (130 bpm) shortly after anesthesia induction with propofol, sufentanyl, and rocuronium. Tachycardia could not be explained by any cause other than the use of rocuronium, which was reverted with sugammadex. Two minutes after sugammadex administration, heart rate normalized, corroborating our hypothesis that rocuronium induced the sinus tachycardia observed in our patient. The patient recovered well from the anesthetic-surgical procedure and showed no further cardiovascular, ventilatory, or neurological changes, being transferred to the post-anesthesia care unit, and finally discharged to the ward. gjreww140916 KEYWORDS Rocuronium, Sugammadex, Anesthesia, Sinus Tachycardia
Read the full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=49662 DOI: 10.4236/ojanes.2014.49029 Author(s) Eduardo Fernandes Orioli Guimarães, Muriel Mofreita Saldanha, Tiago Coelho Fortes, Marcelo Grisolia, Marcos Lopes de Miranda, Carlos Darcy Alves Bersot Affiliation(s) Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. Department of Anesthesia, Lagoa Federal Hospital, Rio de Janeiro, Brazil. ABSTRACT In rare cases, rocuronium has been associated with dose-related tachycardia, probably by a cardiac muscarinic M2 receptor blockade mechanism. We report the case of a 30-year-old female who underwent excision of a branchial cyst under general anesthesia. This patient presented an episode of sinus tachycardia (130 bpm) shortly after anesthesia induction with propofol, sufentanyl, and rocuronium. Tachycardia could not be explained by any cause other than the use of rocuronium, which was reverted with sugammadex. Two minutes after sugammadex administration, heart rate normalized, corroborating our hypothesis that rocuronium induced the sinus tachycardia observed in our patient. The patient recovered well from the anesthetic-surgical procedure and showed no further cardiovascular, ventilatory, or neurological changes, being transferred to the post-anesthesia care unit, and finally discharged to the ward.gjreww140916 KEYWORDS Rocuronium, Sugammadex, Anesthesia, Sinus Tachycardia