Discover Top Posts Tagged with #zombie cells

‘Zombie’ brain cells develop into working neurons

Genetically preventing apoptosis during brain growth allows ‘zombie’ cells to develop into functioning neurons.

#zombie cells #apoptosis #neuroscience #science

Zombie cells are the ones that can't die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list.

I knew it! Zombies.

#zombie cells #cognition #senescent cells #neurodegeneration #biology #brian #science

Zombie Cells Found in Mouse Brains Prior To Cognitive Loss

Study reports senescent cells accumulate in certain brain cells prior to cognitive loss.

The research is in Nature. (full access paywall)

#neuroscience #science #neurology #zombie cells #cognition #alzheimer's

Flushing out 'zombie cells' could help stave off Parkinson's

In work that could open a new front in the war on Parkinson’s disease, and even ageing itself, scientists have shown that they can stave off some of the effects of the neurodegenerative disease by flushing “zombie cells” from the brain.

The research in mice raises hopes for a fresh approach to treating the most common forms of Parkinson’s disease, which typically arise through a complex interplay of genetics, lifestyle and potentially toxic substances in the environment.

But the approach may have benefits far beyond Parkinson’s, with other neurodegenerative diseases – and the ageing process more broadly – all being linked to the ill effects of these “senescent” cells, which linger in tissues after entering a state of suspended animation in the body.

“It’s a completely new way of looking at neurodegenerative disease and finding potential drugs,” said Marco Demaria, a molecular biologist on the team at the University of Groningen in the Netherlands. “For most of these conditions, we don’t have any way to counteract them.”

#Parkinson's disease #brain #biology #zombie cells #senescent cells #neurodegenerative disease #science

Artificial intelligence identifies anti-aging drug candidates targeting ‘zombie’ cells

A new publication in the May issue of Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, demonstrates the power of artificial intelligence (AI) to discover novel senolytic compounds, a class of small molecules under intense study for their ability to suppress age-related processes such as fibrosis,…

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#aging #anti-aging #longevity #zombie cells

Eliminating dead-but-toxic cells occurring naturally in the brains of mice designed to mimic Alzheimer's slowed neuron damage and memory loss associated with the disease, according to a study published Wednesday that could open a new front in the fight against dementia. The accumulation in...

#zombie cells #dead #toxic #alzheimer #mice #dementia