I had this hypothesis that autism and schizophrenia are part of the same disorder. Everyone one that replied to me said they thought I was wrong but would acknowledge that they have a shitload (like 20) of the same genetic markers.
TLDR> SSD and ASD are part of the same disorder. (most likely)
"Schizo/Autism are spectrum disorders but I think they are the same spectrum just in a different dimension."
I feel like nobody understood this. If you didn't think of the spectrum being an X/Y chart then you got it wrong.
Saying "same spectrum" was probably bad wording but it was the best way I could think to describe it with just imagining this up while taking into consideration everything I know about both disorders. Now that I have done more research I can describe it better. They have the same underlying causes in relation to genetics and neurological development. It's all a matter of how your genes are expressed during brain development that determines which parts of each of the disorders you end up having. They both affect many similar parts of the brain but if those parts of the brain or under developed or over developed determines which spectrum symptom you have. It gets more intricate than that though, also the structure of these neurons in these parts of the brain can determine what symptoms you have.
ASD and schizophrenia/psychosis have been proposed to be on two ends of a spectrum related to the social brain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906088/
Conclusion: There is significant boundary overlap between autism spectrum disorder and schizophrenia spectrum disorder.
https://pubmed.ncbi.nlm.nih.gov/27311754/
This next article seems to indicate that SSD and ASD are highly related and that how the genes are expressed in different sections of the brain determines whether it's a schizophrenic symptom or autistic symptom.
Evidence regarding the genetic, physiological, neurological, and psychological underpinnings of psychotic-spectrum conditions supports the hypothesis that the etiologies of these conditions involve biases towards increased relative effects from imprinted genes with maternal expression, which engender a general pattern of undergrowth. By contrast, autistic-spectrum conditions appear to involve increased relative bias towards effects of paternally expressed genes, which mediate overgrowth. This hypothesis provides a simple yet comprehensive theory, grounded in evolutionary biology and genetics, for understanding the causes and phenotypes of autistic-spectrum and psychotic-spectrum conditions.
https://pubmed.ncbi.nlm.nih.gov/18578904/
And this final one also confirms my original hypothesis that it's all the same sort of problem.
Results: Cognitive performance analysis confirms the convergence of abnormalities of people with autism and people with schizophrenia on 1st and 2nd order theory of mind, emotion processing and social perception. Quantitative results show reduced performance in ASD compared to SZ and Ct groups. Differences were observed between ASD and SZ regarding social situation comprehension, visual orientation and visuospatial exploration strategies, and attributional style highlighting different strategies on intentional process. Brain imaging studies show that people with autism present a reduced cerebral activity in several key regions of theory of mind (cingulate regions, superior temporal sulcus, paracentral lobule), and emotional treatment (primary and secondary somatosensory regions), while people with SZ exhibit an inappropriate increased activity in these regions.
https://pubmed.ncbi.nlm.nih.gov/30122298/
It's like... how can everyone know that SSD and ASD have like 20 of the same genetic markers and not put the pieces of the puzzle together. SSD and ASD research teams need to be working together on this problem.
origamiaround
ellievsbear
jbbartram-illu
theartofmadeline
annaxmalina
yousharknotpass
kianamaiart
romaincrisis
jacobvanloon
vaporwave
germansingergirl
