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Mesenchymal Stem Cells production

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Measure height with footsteps!

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#CEKG#CPHI2025#Shanghai#biotechnology

Welcome your visiting

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The Tough Path to Industrial-Grade MSC Exosomes – And How We’re Fixing It

If you’re in #biotech or #CellTherapy, you know: taking MSC-derived exosomes (MSC-Exos) from small-scale research to mass production is hard.

The big challenges? 🔸 Scalability – Flasks & static culture don’t cut it for large batches. 🔸 Batch differences – Slight changes = inconsistent exosome quality. 🔸 Storage risks – Exosomes are fragile; keeping them stable is tricky.

Our new approach: ✔ Microcarriers → Better MSC adhesion & growth ✔ Single-use stirred bioreactors → Smooth scale-up ✔ Harvesting from supernatant → Higher yields, easier purification

This could be a game-changer for #RegenerativeMedicine and #DrugDelivery! What do you think—would this work for your research?

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BIOCHINA 2025 we are Suzhou from 13th to 15th March and waiting for you. Booth No. SC1-005

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Rooted and deeply cultivated cell culture technology.

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SKC800 75L pilot and production stainless steel bioreactor provides new solutions for the development of bioprocesses with its excellent performance and moderate scale.It adopts the biological reaction process control algorithm independently developed by CEKG and has a highly controllable culture environment. Through stirring, temperature, pH, DO, deep ventilation, surface ventilation, peristaltic pump, defoaming and liquid level, weighing, The control of cold spot detection and additional analog input and output provide suitable cell growth conditions to achieve batch culture, fed-batch culture and continuous perfusion culture, thereby achieving high-density culture and high-yield production.

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See you next year!

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Currently, seed cell amplification in the market mostly uses swing-bed bioreactors (such as SKC600 from CEKG) and small stirred bioreactors. CEKG has SKC900 series stirred Single-use bioreactors, with a culture volume ranging from 10L to 2000L, which can not only meet the needs of production amplification, but also help solve the problem of multiple products on the same line.

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The training attracted more than 30 experts and scholars from biotechnology companies and research institutes across the country. During the five-day course, the large-scale culture and seed preparation technology of Vero cells, the research and application progress of viral vaccines based on Vero cells, and the application, operation, sampling, detection, perfusion culture of various types of reactors were carried out. The combination of theory and practice built a systematic and comprehensive knowledge system for the trainees.

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CEKG at CBioPC2024

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CEKG focuses on providing cell culture

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Aseptic handling is a critical factor in ensuring the quality and safety of biopharmaceuticals. Production processes based on single-use solutions are widely used, and it is particularly important to achieve sterile connection and disconnection of pipelines on products such as single-use bags. In order to solve this problem, CEKG has launched aseptic Ttubing taking machines and tubing sealing machines for different size, which can achieve sterile connection or disconnection stably and safely regardless of whether they are in a clean area or not.

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https://www.whcekg.com/en/index.html

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Products are getting better and better. How do you think?