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23pairofchromosomes

Migraine stats:

• Migraine is the 3rd most prevalent illness in the world.

• Nearly 1 in 4 U.S. households includes someone with migraine.

• 12% of the population – including children – suffers from migraine.

• 18% of American women, 6% of men, and 10% of children experience migraines.

• Migraine is most common between the ages of 25 and 55.

• Migraine tends to run in families.

• About 90% of migraine sufferers have a family history of migraine.

Mechanism of migraine:

Dilation and inflammation of cephalic arteries and intracranial extra cerebral arteries cause the migraine headache. The migraine-associated symptoms result from the activation of the sympathetic nervous system caused by the pain. The migraine aura is caused by the neurophysiological phenomenon of spreading excitation/depression. The various mechanisms are tied together in the so-called “parallel theory” of the pathogenesis of the migraine attack

Common symptoms:

Throbbing, pulsating pain – 85 percent

Light sensitivity – 80 percent

Sound sensitivity – 76 percent

Nausea – 73 percent

Pain on one side – 59 percent

Vision changes, blurred vision – 44 percent

Aura – 36 percent

Vomiting – 29 percent

Uncommon symptoms:

• Limb numbness/ limb tingling

• Hypersensitivity to touch - allodynia

• Slurred speech

• Auditory hallucinations

• Hiccups

• Metamorphosis - distortion of body image and perspective

• Olfactory hallucinations - smelling odors that aren’t real

• Excessive Yawning

• Monocular Blindness

• Sever Anxiety

• Fever

• Hives

• Diarrhea - constipation

• Fatigue

• Swollen eyelid

• Food cravings

• Vertigo - feeling as if you or objects around you are moving while they’re not

Action of antimigraine medications:

The abortive antimigraine medications act by constricting the dilated arteries through stimulation of the serotonin 1B receptor. The preventive antimigraine medications act by increasing the tone of the extacranial arteries, inhibiting the mechanism of neurogenic inflammation, or inhibiting pain transmission within the central nervous system.

Drugs used to stop migraines:

• acetaminophen (Tylenol)

• non-steroidal ani-inflammatory drugs ( aspirin, ibuprofen, naproxen)

•Excedrin

• triptans - serotonin receptors agonists (Imitrex, Zomig)

• ergotamine derivatives (Cafergot)

The preventive antimigraine medications:

• anticonvulsants ( Topiramate)

• antidepressants

• antihistamine (Cyproheptadine)

• beta-blockers (Propranolol)

• calcium channel blockers (Verapamil)

Me: I have a migraine

Coworkers, family, friends, non-migraine sufferers in general: Oh, sweetie- drink some water and eat your vegetables! You're just unhealthy and need to take better care of yourself! Then those darn migraines will go away! :):):)

Me:

Me: That's not how it works. That's not how any of this works.

Me: *illness acts up* "I can't do the thing."

Parents: *parents get annoyed* "I'm having a bad day, therefore you shouldn't be sick. Suck it up."

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heyatleastitsnotcancer

When I was a teenager with migraines daily and throwing up regularly I was told it was stress from being bullied. Turns out I have a serious heart condition.

When I was in college and had the worst pain of my life in my abdomen I was told it was an ulcer from stress. Turns out my gallbladder was so full of stones they had blocked access to my intestines and I almost died.

When I was still in college and had severe cramping I was told that my periods were exasperated by stress and that I was paranoid. Turns out an ovarian cyst was so large on my ovary it destroyed the organ by literally flattening it like a pancake.

When I was in grad school and having tremors and passing out I was told I had anxiety from stress and referred to a psychologist. Turns out my brain was literally not getting enough oxygen to function from my heart condition.

When I was 25 and my bladder stopped working which did not allow me to pee for days I was told that it was stress and that it was mind over matter to urinate. Turns out the muscles in my pelvic floor are in constant agonizing spasm.

My physical symptoms have been dismissed as manifestations of stress most of my life by both doctors and loved ones causing permanent damage to my body, pain, and loss of quality of life. We need to stop dismissing teenager’s and women’s symptoms as stress and start taking them seriously. Stop dismissing illness as stress simply because of a person’s age, gender, sexuality, ability, race, or socioeconomic status.

chronicallyrebellious

#PREACH

mikenudelman

The 14 smartest purchases to make in your 20s.

mikenudelman

9 changes to make in your 30s that will set you up for lifelong success.

spooniestrong

The Magical Spoon Dog! 🥄🐶

Reblog to replenish your spoons! 💙

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this-is-cthulhu-privilege

trenchcoats-anonymous-deactivat

I can smell the entitlement in the air

volcel-official

Oregon was a mistake

thevoluntaryist-deactivated2018

faedreamer-deactivated20180128

Oregon, what you doin???

earlgreytea68

I think I am most bewildered by how many people seem to think that you spend the rest of the day reeking of gas fumes if you touch a gas pump. Do they think you pour the gas all over yourself…? Why are these gas fumes clinging to you through your day such that you will not be fit to be around other humans…?

antyc67

I didn’t even know there were places left that let you pump your own gas.

ladyoftheteaandblood

@antyc67 in Britain we pump our own.

gehayi

I didn’t know there were any stations left where people don’t pump their own gas. Every gas station I’ve ever seen has been self-service since the 1970s.