@astudyinphd said: OMG! That’s great! And I totally agree with you on the new...
Thanks! And thanks for the book rec, I’m definitely gonna check it out! The summary sounds awesome.
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@astudyinphd said: OMG! That’s great! And I totally agree with you on the new...
Thanks! And thanks for the book rec, I’m definitely gonna check it out! The summary sounds awesome.
Researchers discovered a protein found naturally in cells is responsible resistance to treatment in breast cancer.
Researchers have discovered that a protein found naturally in cells that provides some protection from viruses is responsible for creating mutations that drive resistance to tamoxifen treatment in breast cancer. Because the protein, known as APOBEC3B, is found in elevated quantities in other kinds of cancer cells, the finding explains differential responses to treatment and opens the door to boosting the effectiveness of tamoxifen and related breast cancer therapies that inhibit the ability of estrogen to stimulate tumor growth.
Faster and better healing of infected wounds using negative pressure technique
Shorter wound healing time, fewer dressing changes and the opportunity for earlier discharge from the hospital. These are some of the benefits of negative pressure wound therapy to treat wound infections in connection with vascular surgery at the groin. The method, which has become increasingly common, is also cost-effective. This is shown in a thesis from Lund University in Sweden in which the method has undergone its first major scientific evaluation in deep perivascular groin infections after vascular surgery.
“On average, the wound healing time was almost cut in half for patients who received negative pressure wound therapy – from 104 days to 57. The in-hospital care time was also reduced by a week, to an average of 13 days compared to 20”, says Christina Monsen.
The image shows how the negative pressure treatment of a wound works. Illustration: Stine Høxbroe, Copenhagen, Denmark
16th Oct - Day 14 of the @gradblrchallenge
No photo today, because while I did get quite a bit of work done, it was on the couch in my pjs and nobody wants to see that. Anyway, I finally got into data analysis proper and man, let me tell you, it is going well. I’d kind of had the impression already that there weren’t going to be that many road blocks once I got to this point. And it seems blessedly true. I’ve got about two thirds of the numbers I need already. The only major difficulty I think is going to be the plots, as I mentioned yesterday. I’ll try to talk to my colleague about that sometime next week and see if he has any thoughts on the matter.
Working with R has been an experience, to say the least. I keep oscillating between exhilaration when something works and wanting to break the space-time continuum to punch past!me in the face for committing to a project that requires programming in a language I know nothing about. Today was the former category. Particularly when I wrote a piece of code from scratch to loop over all subgroups and calculate their average diameter and it worked on first try. Man, that was something.
Work-life balance: 1. Not work on the weekend 2. Feel guilty Sunday night 3. That’s basically it
Everyday in grad school
Gradblr Challenge - Oct. 13th-16th
I missed the last few days for a variety of reasons, but I’m back and ready for the new week! I’ve been working on my midterm paper which is due at the end of this week, and I have an important experiment I’ll be running tomorrow in lab. Later this week I’ll be heading to the mountains of New Hampshire for a departmental retreat. I am loving the fall weather already here in Boston, and I think New Hampshire will be beautiful this time of year. I’m excited to get outdoors and get to know more about the department, but I hope I’ll be able to finish everything I need before I go so I’m not stressed and can actually enjoy the time off. I hope everyone had a great weekend and is ready to start another week!
Last week:
ran a qPCR to see if my samples had bacteria contamination
went to an afrobeat festival with my roommates. It was awesome! The percussion and sax were on point.
thoroughly read the paper for my midterm
went to a dumpling festival. Super delicious :)
This week:
finish my midterm paper/critique
run HPLC/MS on my heavy-labeled samples
analyze my qPCR and MS data
retreat time!
@gradblrchallenge
Day 10 - Gradblr Challenge
I did it! I actually did it! I got up at 5:30am today, people. This is not a drill. I’m so proud that I only snoozed once. The new clock app on the latest iOS for iPhone is super helpful for setting alarms, and their wake up tones are gradual and won’t aggressively wake you up. Highly recommend checking it out! I’ll try and keep up this wake up time tomorrow.
Things I did today:
got my life together by setting up my monthly calendar and weekly plan
did some laundry and got groceries
finally replied to an email from my friend back home. It’s so good to have someone I can vent to and share this experience with.
extracted some bacterial DNA
Overall, a pretty typical Wednesday. I did finish my audiobook the other day (I binge listened to the last 2 hours it was so good!). Anyone have any audiobook suggestions I can check out? Maybe something light and entertaining? I hope everyone had a great and productive day! :)
@gradblrchallenge
Science Aesthetics
I was feeling inspired last night, so I decided to make this purely for fun.
To the moon and back: Cold, dark nights clutching thermos flasks of hot coffee. Machinery whirring as telescopes trace a star across the sky. Intricate, geometric drawings of the celestial sphere. A messy bun and a NASA t-shirt. Filling in the logbook while punk rock blares in the background to keep you energised and awake. Pictures of nebulae and galaxies everywhere, because pretty space pictures is half the fun. Annoyed huffs every time someone mentions their star sign.
Natural Philosopher: Long, intellectual debates in coffee shops about mathematics, physics, philosophy. Chalkboards covered with equations and calculations in a precise, curving handwriting. That Eureka moment while deep in thought, expressed only with a small smile and a scribbled proof on the back of a serviette. Chaotic desks in front of bookshelves groaning with old textbooks. Antique lab equipment as functional decor.
“Trust Me, I’m a Scientist”: Large computer screens running freshly-typed code. Neat lab books and PDFs of journal articles. The smell of whiteboard markers. Polished new equipment in a tangle of cables, hooked up to a digital oscilloscope. Exact amounts of chemicals in rows in metal shelves. Resting your feet up on the bench after a long day in the lab. The satisfying hum of your colleagues as they work on their experiments around you.
Science Expedition: Dirt under your nails and a loosely-bound collection of field notes. Plant clippings carefully taken to be analysed back in the lab. Soft fur on tough, wild animals. The bitter smoke from eco-friendly firewood while you roast marshmallows and listen to a supervisor’s witty stories. Free-handing diagrams while looking through a microscope. Sketching flowers and that gorgeous ocean view from your last field trip. Reading Darwin on the bus home but falling asleep on your lab partner’s shoulder out of sheer exhaustion after the first three pages.
Life is a Science: Scrolling past an anti-vax facebook post and resisting the urge to burn down the internet. Shiny dissection kits and the sharp smell of formaldehyde. Making time to work out and pack a healthy lunch because your mind is sharpest when your body is well. Debunking the latest superfood fad with peer-reviewed journal articles. Making friends with some of the nicer med school kids in anatomy class. Colour-coded, neatly labelled diagrams and a thousand different terms memorised. Getting a double-helix DNA sculpture for your desk.
What they show on TV isn’t real hacking: Rubbing your eyes after staring at a screen for five hours straight. Having a blank keyboard because all the letters are rubbed off already. Energy drinks in strange colours at strange hours. Being fluent in four different coding languages. Circuit boards and printouts. Ones and zeroes. Running jokes about turning everything off and on again. Rage-quitting when you realise you forgot a comma or a colon somewhere. Black screens with brightly coloured lines. The comforting click-click of fingertips tapping keys. Applying to intern at Google every three months because maybe they’ll take you this time. Writing a piece of code to do something simple just because.
On managing academic stress
(image above is click-through link to related UC Berkeley article)
Most of us have probably heard at some point in our lives that stress is not entirely a bad thing. Acute stress, such as having an upcoming deadline or being about to take a test, can boost your motivation to rise to the challenge and “get it done”. However, chronic stress (often times characteristic of “the grad school experience”) can have adverse (and enduring) effects if not managed properly. As someone who has an (undiagnosed) impulse control disorder that is exacerbated stress and who was diagnosed with IBS during my third year of grad school, I know this all too well. It wasn’t until I started having IRL conversations with other academics that I realized that academic stress is both real and commonplace.
Apparently, I wasn’t the only one with IBS, waking up in the middle of the night feeling like I was having a heart attack (if you haven’t experienced this, count yourself lucky), and reaching those times of feeling overwhelmed/burnt out. It also didn’t help that there’s this notion that stress just comes with academia (i.e. it is something to be expected and handled) and nobody really feels comfortable talking about openly. It’s almost as though to admit that you are feeling stressed out is equivalent to being weak. Before I proceed, allow me to try to convince you that this notion is antiquated and incorrect. Academia is stressful for pretty much everyone who is human and academic stress comes in many flavors throughout an academic career. Some examples include: first year stress (esp. if you did not major in neuroscience or psychology), stress of picking lab and becoming a new member, grant-writing stress, project trouble-shooting stress, oral presentation stress, comp/qualifying exam stress, lab drama stress, publishing stress, thesis-writing and defense stress, finding a job stress, tenure-track stress, out of funding stress and the list goes on. Furthermore, some would say that the “academic climate” now is more competitive and cut throat that it used to be (way back when in the 80s, 90s). So there. More stress.
The first step is to identify stress for what it is and to determine your specific triggers so that you can better develop coping strategies. Also, try to be specific as to what aspect of the stressor throws you over the edge. Is it timing? Lack of controllability? Working with others? Not feeling the sense of mastery you want? Poor lifestyle? You get the picture.
Below are a set of points that have been helpful to me. This list is by no means all-inclusive, so feel free to customize it. This list is more about providing a starting point of ideas as to how to manage your stress (and preserve your sanity).
1. Take care of yourself: Eat, sleep, and be active. Also, cut down on your vices or substitute for less harmful ones. Sure, sounds easy enough. But not really. During my PhD, I worked outside the city and my workday was from 9:00AM (all aboard the NKI shuttle at 8AM though) until 6:00PM. This means that I started to get ready around 7AM and was back home around 7:30PM. Every day. For years. To make matters worse, I was going to bed at 1-2AM. BAD IDEA. Now I make it a priority to get at least 6 hours but usually aim for 7-9 (yes, 9!). If you are getting less than 6 hours in regularly, you are likely not sleeping enough. Also, I’m sure many of you are familiar (i.e. guilty of) being so busy you forget to eat. Don’t. Give yourself options: bring snacks to lab, have food delivery numbers handy in a pinch or even buy back-up tie over meals to keep in the break room (i.e. yogurts, a loaf of bread, cheese, cold cuts, frozen dinners, etc.). Also, try sneaking in a little exercise into your life by walking to work, picking up a training/workout class, getting into intramural sports (more likely if you work somewhere that has an undergrad campus), or even just dancing by yourself in the comfort of your own house. Basically, find something that helps you work up a sweat. If you’re at a school w/ an undergrad campus, chances are you have a wealth of activities available to you at little or no cost (i.e. access to pools, gym facilities, fitness classes, etc.).
2. Plan, organize, and prioritize. These are all related to time management skills. Unfortunately, there is no grad school class on time management so most grad students have to adopt a trial and error approach. Others, like myself, had a gracious PhD mentor that taught them how to timeline/schedule experiments. (Side note: I did my PhD in a developmental behavioral neuroscience lab so scheduling was a must.) There is really something to be said for putting down what you need to do on paper. I know it’s stressful to see your to-do list (which usually seems never-ending) but it helps keep important stuff in mind and it feels really good to cross things off :) Let your to-do list motivate you, not paralyze you! Also, keep in mind the order of importance of things as you work on the list. Ex. I use iCal to schedule experiments, meeting, events, etc. My phone does this thing where it synchronizes Facebook events, Google calendar, and iCal so that when I look at a day, I see EVERYTHING that is happening each day and when/where. I also keep a Post-It note stuck on the right side of my laptop (I bring it to lab) with things that need to happen ASAP. On the wall above my desk I keep a handwritten list of things that need to be done in lab over the next couple of weeks (on a continuous basis or for a specific cohort of animals, etc). Developing time management skills is important because it’s easy to forget to do something you have not made time for! By this I mean that what doesn’t get scheduled, typically doesn’t get done :/ The responsibility is yours. Also, if you are stressing about a specific aspect of a project or getting a particular data-set, ask your PI what they think your priority should be (this may be something they need for a grant, talk, etc.).
3. Create a social support network and maintain healthy social relationships. You know, people you can talk to (and let your guard down with). These may be friends, family, significant other, colleagues, lab mates, conference buddies, neighbors, etc. It is often beneficial to have a mix of people (i.e. the have been there forever, the school/lab ones, outside academia). Swap stories with lab mates, peers, colleagues you trust instead of bottling up everything. I think it gives a sense of solidarity since a lot of the stress lab/academic situations are commonplace. Keep in mind that school/work struggles are not exclusive to academia and you can often gain meaningful insights and a different perspective from people outside academia. One last thing on this: don’t neglect your own role when the time to buffer someone else comes! You can’t take all the support but not give any.
4. Learn how to say no (know your limits). One of the easiest ways to bring in paramount stress levels into your life during grad school/postdoc is to say yes to more than you can handle. In academia ideas and projects are constantly being formed/pursued and it is not unnatural for students/postdocs to have more than one project. This is ok but avoid spreading yourself too thin. I, like many, have been guilty of this. Some things I’ve gotten done and some I’m still trying to push out. Oh well. If you’re feeling stressed out, (see #2 and note below).
Reminder: PIs know that you’re working on project X. But they usually don’t factor in all the little details that go into making project X happen, such as breeding, habituation, surgeries, post-op rec periods, time in b/w tests, etc. It is your job to remind them!
Note: Doing #2 will help you tell your PI exactly how your time in the lab is spent. It’s WAY easier to postpone starting something or reduce your role if you have PROOF that you have no time for it. If it’s really important, compromises will be made (hurray!).
5. Make time for hobbies. Even better, cultivate new ones. Working really hard does not mean that all you do is work. Try to become really good at something other than science :) Find a variety of interesting, fun and/or enjoyable things to do outside of lab. It helps to have hobbies of varying intensities (some active, some passive) so that you have options if you come back too tired or what not. Have more low-key ones (ex. cooking*, singing, drawing/painting, knitting, becoming an expert at ______, delve into a decade, explore a music genre, start a collection) and active (i.e. martial arts, yoga, train for a marathon, pick up a new dance, teach your body how to do something new or just walk around).
*Learning how to cook gives you a head up on #1.
6. Find your ground. This one is really open-ended as it means different things to different people, but it’s important because it helps you keep connected to yourself. It may include (but is not limited to): talking to your relatives (especially the older ones) regularly, keeping in touch with your cultural roots through organizations/clubs/meetups, volunteering, going to church, meditating, developing your spiritual life, introspection, etc.
7. Stay positive. Avoid falling down the black hole of discouragement and despair. Way easier to get sucked in than it is to claw out. If you let yourself go you will need to be aggressive about obtaining new outlook. And possibly outside help. Remember that misery loves company and protect your positivity. Being positive despite adversity is a choice. You have the power to decide. More on the value of thinking happy thoughts here.
8. Give yourself a reality check. From an intellectual standpoint, there is some sort of a re-wiring that happens when you’ve been in academia for a while. It’s hard to describe because it constitutes different things by career stage and by people. In my experience, this transformation happened towards the end of grad school. It’s around this time that people often ask themselves: WHY AM I DOING THIS? WHAT IS THIS FOR? WHAT DOES IT ALL MEAN? For me, the result of pondering these things resulted in a personal epiphany that all of this (i.e. science, academia, my thesis) was bigger than myself and only a limited part of the world. It does not define who I am as a person, and it will be pretty much irrelevant if the world goes to shit a la Walking Dead or Revolution. Heck, there’s people in the world right now worrying about whether or not they will live to see tomorrow. It was a weird mix of learning how to stop sweating the small stuff and focusing on moving towards the big picture, feeling privileged to be able to pursue doing research, while also understanding that there are things beyond your control and that sometimes you can only control the way you handle a situation and what you do to remedy it.
9. Go on vacation. This one’s self-explanatory. Try to avoid the compulsion to check your work e-mail :) If you opt for a stay-cation, make it a point to disconnect.
This is really important,
Gradblr challenge!
Reblog & add something little/silly that you’re going to do for self care today.
I’m going to eat and drink my coffee without checking my emails!
I’m going to make chocolate chip cookies to help fight my anxiety! Will post pictures when they are done :)
Watch The Devil Wears Prada. Because if Andy can make it - then so can I.
i’m going to play an hour of overwatch without any regrets
I wrote a very long letter/email to a friend back home about my Boston adventures. Now I also want to watch The Devil Wears Prada.
Gradblr Challenge - Day 9
Just a quick update for today. I met with my PI and we discussed my data from the past week. Some of the results were a little strange, so I’m going to be doing them over using different replicate samples. We also discussed the design of my main project, which is basically to develop a new method in this field. There are so many potential caveats, but I guess that’s why it’s a rotation project and not my actual thesis. We’ll see if it works out!
I also set up an overnight bacterial culture and went to class. My first day trying out my morning routine wasn’t the best, as I couldn’t help but snooze a bit. But I did get up earlier overall, a baby step, and I’m giving myself the week to change things up because this habit has become so engrained in me. I’ll keep you all posted on how it goes. Hope everyone had a great day!
@gradblrchallenge
Women in Science
Today, Ada Lovelace Day, sees the launch of an initiative to celebrate women in maths and computing. As a new branch of the existing Suffrage Science scheme, it will encourage women to enter science, and to reach senior leadership roles. Despite much effort, gender imbalance persists in the fields of maths and computing. Suffrage Science aims to make a difference. The scheme was founded five years ago by the MRC Clinical Sciences Centre. It began with a life sciences focus before expanding in 2013 to include women in engineering and the physical sciences. The new branch recognises the increasing importance of mathematics and computing to the life sciences. At the launch event, 12 women (pictured) will receive awards to celebrate their scientific achievements and ability to inspire others. Every two years, the award will be handed on to a new group of women, thereby extending the scheme’s reach.
Written by Deborah Oakley
Image by the MRC Clinical Sciences Centre
Image copyright held by the MRC Clinical Sciences Centre
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It’s finally here! Thank you guys so much for supporting and being part of my life. I cannot tell you the inspiration, motivation, and happiness you all have given me in the few months since I’ve made my studyblr. Okay I’ll stop being mushy :)
Please read the rules below for how to enter, and I will announce the winner on November 2nd, 2016! So, heres a big giveaway that I’ve been saving up for for weeks! Here are the 5 things that you will receive if you win!!!
Here is what you will win:
1- 10 pack of Staedtler Triplus Fineliner Brilliant Colours
2- 1 Blue Fjallraven Kanken Backpack
3- 15 pack of Zebra Mildliner Cool Soft Colour Double-Sided Highlighters
4- Ban.do Sticker Book
5- 20 MT Washi Masking Tapes
RULES:
Must be following me ( @zeestudies ) (It’s a 5k follower giveaway, after all :P)
Must reblog (likes are for bookmarks) You can reblog as many times as you would like!
If you won, I will send you an ask on November 2nd, 2016 and ask for your PO box or mailing address, so please be comfortable with me asking for that :]
No giveaway accounts, please!
****This is optional, but if you have the financial means to afford these items, please try to reblog this less, as this is for people who cannot afford these luxury items :)
I LOVE YOU ALL SO MUCH!!!! GOOD LUCK :)
Congratulations Zee!! You deserve all the goods! <3
12102016 - day 10 of the @gradblrchallenge
Today in point form: - We discussed the impact of low fertility rates on Singapore’s labor force and government responses to that. - Started work on another essay paragraph, this time to do with tracking changes in educational policy to see how holistic education has been emphasized - Finished 2 readings for tomorrow’s tutorial - Today’s lecture was about how identity can lead to formation of groups and how that can lead violence, especially when it has to do with power. - Fed cats! I was so happy to see them again even though it took over an hour - Started revision proper for my midterm on Thursday!
astudyinphd replied to your photoset:Gradblr Challenge: Days 6-8 Hey everyone, I’m...
What you’re describing about always feeling like next week will be the week where I’ll be more in control and have more of my shit together is SO accurate. Keep updating about your morning progress! I’m really excited to see how it changes for you!
curiousgradstudent replied to your photoset:Gradblr Challenge: Days 6-8 Hey everyone, I’m...
Looks like a great trip! Keep us posted on the morning routine. I’ve fallen into a bad habit of snoozing too… :-(
@astudyinphd Thanks, K.T.! It’s good to hear I’m not the only one feeling like this. Hope everything is going well for you!
@curiousgradstudent I’ll keep you posted! Hopefully we can figure out a way to break the habit :)