There's a lot of things that don't get explicitly called out in the show. For example, I don't think I've ever even seen anyone point out that Jackie sexually assaulted Jim. She cornered them, felt them up and was definitely going to go further if she didn't hear the nose jar break. And then several episodes later she and Jim were sharing a glass having the ol' heart to heart. Does the existence of this scene mean OFMD supports rape culture? I guess you could say that if you really wanted to, but a more charitable interpretation would be that the show didn't think it was even necessary to have Jim or someone else say out loud that sexually assaulting people is not ok. Jackie is very obviously not a good person by any stretch, she's basically the local mafia boss, so it's only expected that she'd be doing a lot of problematic shit. But, in her own words, she's still a human being who has feelings, and is shown to be capable of forgiveness and empathy in some cases. In a way she called herself out. She was going to kill Jim and then she was like "nah fuck this shit, run away kid, don't end up like me".
No, the show didn't directly call the crew out on making fun of Izzy. But it took Izzy's disability very seriously. He was shown to be severely affected by it and very demoralised, sinking into alcohol addiction and sheer despair, hitting rock bottom and humiliating himself. And the crew, half of which still hated him at this point, came together to help him. They themselves were suffering, but chose to try and work through it "as a crew" by doing something kind. Not just make him a wooden leg, but turn it into a work of art, symbolically transforming Izzy's disability into something beautiful. Using the unicorn figurine - something else that was "broken" and "useless", something that became an outlet for Izzy's own self-hatred. They gave it a new life and turned it into love instead. If this isn't the very opposite of ableism, I don't know what is.
And it wasn't the type of character arc where "the power of love" magically makes the disability go away etc. I hate those. We still see Izzy being affected by it. He had to completely retrain how to walk, move and fight. We see him lean a lot on various surfaces and other people. He's still shown to drink occasionally and be in pain, but he's clearly at peace now and genuinely learning to be happy and appreciate life. Even if some of his ways of moving on aren't "correct", he's still moving on. And, don't get me wrong, I hate that he died and thought it was a shit writing choice, but they made sure that we saw that he didn't die because of his leg. He was standing right behind Ricky, the first in the line of fire, being disabled had nothing to do with it (yeah it was dumb that he'd choose to be the one to lead Ricky and didn't take his gun away, but that's a whole different issue).
So, idk, I just think it's unfair to call the show ableist when it clearly went to such lengths and put so much heart into giving Izzy such a wholesome and powerful character arc centered on disability. I've seen a lot books, shows and movies that claimed to be "empowering" for disabled people but only felt condescending or cheesy at best, or resorting to toxic clichés at worst. But OFMD was the one that made me feel so seen. I'm not saying the show is perfect, especially when it comes to S2, but I don't think ableism was one of its faults.