The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring cannabinoids. Cannabinoids are compounds found in cannabis plants.
Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including:
Sleep
Mood
Appetite
Memory
Reproduction & Fertility
How does it work?
The ECS involves three core components: endocannabinoids, receptors, and enzymes.
Endocannabinoids
Endocannabinoids, are molecules made by your body. They’re similar to cannabinoids found in the Hemp and marijuana plants, but they’re produced by your body.
These help keep internal functions running smoothly.
Endocannabinoid receptors
These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action.
There are two main endocannabinoid receptors:
CB1 receptors, which are mostly found in the central nervous system
CB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells
Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to.
Enzymes
Enzymes are responsible for breaking down endocannabinoids once they’ve carried out their function.
What are its functions?
The ECS is complicated, and experts haven’t yet determined exactly how it works or all of its potential functions.
Research has linked the ECS to the following processes:
appetite and digestion
metabolism
chronic pain
inflammation and other immune system responses
mood
learning and memory
motor control
sleep
cardiovascular system function
muscle formation
bone remodeling and growth
liver function
reproductive system function
stress
skin and nerve function
These functions all contribute to homeostasis, which refers to the stability of your internal environment. For example, if an outside force, such as pain from an injury or a fever, throws off your body’s homeostasis, your ECS kicks in to help your body return to its ideal operation.
Today, experts believe that maintaining homeostasis is the primary role of the ECS.
The entourage effect is the reaction that occurs between the interactions of “minor phytocannabinoids” and the more well-known cannabinoids such as THC and CBD. It is believed that cannabis synergy comes from all compounds, including terpenes and other cannabinoids working in concert. It is a synergistic bond between the body’s endocannabinoid system (ECS) and all the compounds found in the hemp plant.
As mentioned, the most well-documented cannabinoids that have therapeutic value by researchers are THC and CBD. However, since 1988, Dr. Mechoulam and Prof. Shimon Ben-Shabat, the discoverers of THC, believed that the ECS demonstrated an entourage effect in which minor phytochemicals, such as cannabinoids and terpenes increase the activity of the body's primary naturally occurring cannabinoids, anandamide, and 2AG —making “minor-cannabinoids” not so minor after all.
To reiterate, the ECS and cannabinoids promote restoration of balance in the mind and body when all working together.
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10 Potential Health Benefits of CBD for Older Adults
Cannabidiol or CBD oil has become increasingly popular in the United States as a remedy for a variety of ailments. Many older adults have also embraced CBD to treat everything from depression to chronic pain.
Cannabidiol, otherwise known as CBD, is derived from the Cannabis sativa plant, also known as marijuana or hemp. More than 80 chemicals called cannabinoids have been identified in the Cannabis sativa plant. THC, the chemical that causes a “high,” is the active ingredient in marijuana. However, cannabidiol is most often obtained from hemp, and contains just trace amounts
of THC.
There have been few side effects noted in CBD use studies, but they do occur and can include dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. CBD can also interact with other medications, such as blood thinners.
The benefits of CBD are increasingly being researched and documented. Here are 10 areas in which CBD use has potential benefits for seniors.
1. Anxiety
CBD may have the potential to help manage anxiety. Researchers think that it might change the way that the brain’s receptors respond to serotonin, which is closely associated with mental health outcomes. In one study, social anxiety sufferers were able to give a speech more easily with the help of CBD. Additionally, research done with animals has shown decreased expression of anxiety with CBD. CBD can help promote stress reduction and lead to fewer physiological effects from anxiety, like increased heart rate.
2. Neurodegenerative Disorders
CBD might be a promising product in the fight against neurodegenerative diseases. A loss of neurons in different parts of the nervous system leads to a corresponding decline in cognitive and motor functions; these conditions, such as Parkinson’s, dementia and stroke, cause the brain and nerves to deteriorate over time. Researchers are actively studying brain receptors to uncover the ways that CBD could help.
We discussed how CBD can lower inflammation. Because inflammation can actually make neurodegenerative symptoms worse, CBD can promote good brain health through this mechanism, too. Keep an eye out for more studies to come on this subject. CBD could evolve to become a useful tool to turn to in the fight against neurodegenerative diseases.
3. Mental Health & Mood-related Disorders
As people age, they experience major changes as a result of getting older. Health usually declines and people are more likely to deal with loss and grief. Additionally, social isolation, depression and loneliness may all play a factor in decreased mental health. CBD has been shown to help with these and other related conditions. CBD may interact with brain receptors that are involved in mood regulation. CBD can promote stress reduction, mindfulness and improvement in cognitive function. This powerful combination can strongly contribute to how the mind perceives its situation while enhancing mood.
4. Sleep Quality
Sleep issues and insomnia challenge many individuals, and older adults are no exception. This may be caused by changes in sleep patterns as individuals age. Additionally, medical conditions and prescribed medications further complicate things.
Prescription sleep medications can be effective. However, their use comes with long-term concerns. They may lead to dependence, addiction and even worse sleep quality over time.
CBD can help promote calmness and relaxation. Higher quality sleep can be the end result. This can be a natural way to lead to more regular and helpful sleep for older adults. Plus, it can reduce the need to take prescription sleep medications.
5. Pain Management
Around half of the older adult population lives with arthritis. Compared to traditional pain medications, CBD can be a compelling alternative as a natural and potentially safer remedy. Studies have indicated that CBD can reduce inflammation while alleviating pain. Conditions improved include joint pain, arthritis and multiple sclerosis.
6. Bone Health
Keeping bones healthy can be a challenge, especially for seniors living with osteoporosis. Bones become more fragile and vulnerable over time, making them more prone to breaking. For these reasons, seniors often experience significant pain and a propensity for fractures when falls occur. In addition to reducing inflammation and promoting cell repair, research shows that CBD may aid in strengthening bones. It can also promote the body’s ability to heal. While more research is needed, results in this area so far are promising.
7. Addiction & Dependence
When older adults are confronted with an illness, prescribed medication will usually follow. Tolerance may build for many medications that are taken over time. In some cases, addiction or dependence can be the end result. This can cause permanent damage to the body.
CBD has been shown to alleviate some conditions that involve opioids, generally without significant side effects. On top of that, CBD can aid in combating developed dependencies that grew out of the use of prescribed medications. It appears that CBD has the potential to help fight relapses and assist in overcoming withdrawals that develop during this time.
8. Heart Health
Heart disease is the leading cause of death for older adults. A top contributor to heart disease is high blood pressure. CBD has shown to be very promising as an alternative and natural treatment for high blood pressure. One recent study determined that it lowered the resting blood pressure of the study’s participants. Additionally, researchers administered stress tests and found a positive stress response in individuals evaluated in the study. Another study suggests that antioxidant properties of CBD can aid in lowering cardiac inflammation and deter the death of related cells that results from oxidative stress.
9. Cancer Treatment
CBD may help alleviate the symptoms of cancer along with the side effects stemming from treatment. In fact, CBD has shown a reduction in tumor growth in animals. It may even help the body absorb medications better or increase their potency.
Here, CBD may positively manage inflammation and change how cells can reproduce. CBD could also have the capacity to inhibit the growth of some types of tumor cells and stem their ability to reproduce efficiently.
10. Appetite Stimulation
A major health concern for seniors is malnutrition due to loss of appetite, whether due to medicaiton or age. This can lead to unnecessary and unwanted weight loss, muscle and tissue weakness, and other health issues. Marijuana has been studied extensively in this area, and is proven to enhance appetite in its users. CBD can stimulate appetite as well, according to some studies. In this way, it can be beneficial for seniors combating malnutrition and appetite loss.
Conclusion
Scientific research takes time and effort. With a broad range of CBD brands exploding on the market and the potential health benefits of the product coming to light, researchers have only just begun to scratch the surface on the ways that cannabinoids can promote wellness in seniors. In early studies, CBD has been shown to be very promising in improving a variety of ailments and conditions.
CBD is readily available over the counter in many forms. Older adults should talk to their doctor, pharmacist or home health provider before starting a CBD regimen. It’s important to determine if CBD treatment is the right option and make sure that no drug interactions or concerns exist. Also the stigma of marijuana and CBD use can be powerful; family members or the physician may harbor some negative associations to CBD and related products. Home health providers can step in to advocate for their patients who wish to use CBD to manage pain or anxiety. Providing educational materials and promising research on CBD to family members and skeptics should be a goal if you are offering CBD as an option in a home health regimen.
Written by: Brett Shay is the CEO of CareBridge Academy, a certified nurse aide and home health aide training school located in Philadelphia. He also leads Chosen Family Home Care, which is one of the nation’s only agencies dedicated to addressing the needs and challenges of the LGBTQ community and provides culturally competent care to the diverse local population.
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