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Self Reflected, by Greg Dunn.

“...the most complex and detailed artistic depiction of the brain in the world, featuring an 8' X 12' gilded reflective microetching of a sagittal slide of the human brain.”

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Rendering of a reconstruction of all mitral cells in the larval zebrafish olfactory bulb, with cells coloured according to the glomerulus they innervate. (Image courtesy of Adrian Wanner/ Friedrich Miescher/ Institute for Biomedical Research/ Nature Neuroscience)

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The vertical occipital fasciculus, a major neural pathway rediscovered after disappearing from the scientific literature for a century.

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Drawings of nervous tissue by Santiago Ramón y Cajal. 

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The odd beauty of 60-year-old preserved brains from the Texas State Mental Hospital. 

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[neuroimages]

matteofarinella

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3D model of a nerve terminal shows the distribution of 300,000 individual protein molecules involved in neurotransmitter recycling.

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3D reconstruction of nerve cell connections in the mouse retina. From Kim, et al. (2014). The crowdsourced wiring diagram may have revealed a time-delay neural network that makes certain cells sensitive to motion in specific directions.

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Computer-generated reconstruction of three pyramidal neurons, showing differences in the distribution of myelin (shown in white) along their axons. Daniel Berger/ Giulio Tomassy/ Harvard University.

White matter might matter much more than we thought.  

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"Like the entomologist in search of colourful butterflies, my attention has chased in the gardens of the grey matter cells with delicate and elegant shapes, the mysterious butterflies of the soul whose beating of wings may one day reveal to us the secrets of the mind" - Cajal. 

Pyramidal neurons and their dendrites visualised with patch clamp fluorescence microscopy. Alexandre William Moreau/ Institute of Neurology/ Nikon Small World Competition.

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Membrane-labelled subset of neurons in the brain of a living zebrafish imaged with an adaptive optics microscope in two-photon excitation mode. Eric Betzig Lab, Janelia Farm Research Campus.

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A top-down 3D view of the cortico-connections originating from multiple distinct cortical areas of the mouse brain, visualized as virtual tractography using Allen Institute Brain Explorer software. From Oh, et al. (2014). 

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3D-printed brain sculpture, from 21st Century Self Portrait by Chicago-based artist Joshua Harker. 

[yaleuniversity]

In celebration of Brain Awareness Week, here’re pictures from the Brain Tumor Registry at the Harvey Cushing Center!

Harvey Cushing (Yale class of 1891, Sterling Professor of Medicine in Neurology) was an obsessive cataloger, and the Cushing Brain Tumor Registry, is an immense archive of over 2,200 case studies which includes whole human brain and tumor specimens, microscopic slides, journal notes, and 15,000 photographic negatives dating from the late 1800s to 1936.

The Registry is a unique resource that documents the history of neurological medicine from its beginning.

Learn more about Cushing, the Brain Tumor Registry, and the “Brain Society” →

Photos: Terry Dagradi

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Brain grenade resin figure by Emilio Garcia. 

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4,000-year-old brain preserved after boiling in its own juices. Discover/ Altinoz et al. (2013)

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3D reconstruction of 20,000 serial electron micrographs showing a 379-neuron visual motion detection circuit in the fruit fly retina. From Takemura, et al. (2013).