Neuropsychiatric Research Center

[neuropysch]

Caregiver Burnout During the Holidays

The holidays can be a joyful time. Celebrating with family and honoring your traditions while caring for a loved one can feel good and fulfilling. On the other hand, most busy caregivers find there’s even more to do during the holidays. Caregiver burnout is higher during the holidays, but you can take some proactive measures to break this cycle.

Holiday Season Burnout

To break the cycle, we must first understand why burnout occurs. Most individuals find the holidays a more stressful time of year. Shopping, entertaining, decorating, and gathering with family require a lot of planning on top of your everyday routine. A caregiver’s duties are already stretched thin without the added burden of the holidays.

The holidays are a busy time for most people, and caregivers can’t always count on family to help with the extra duties. In addition, traveling with your loved one to a family gathering or outing may not always be possible. Elderly individuals are not always tolerant of crowds, added noises, and people they may no longer recognize. Some may even become agitated, verbally abusive, or combative in public or at home.

Celebrating the Holidays as a Caregiver

Caregiver burnout can happen any time of year. Practicing these 3 simple things can help get you through the holidays and beyond!

·        Communicate- Talk with family about any changes since their last visit. Involve them as much as possible in the planning. Be upfront about boundaries and time limits.

·        Self-care- As the old saying goes, “you can’t fill from an empty cup.” Get enough sleep, take the help when offered, and scratch “perfection” off every list. Find ways to fill your tank, like listening to Christmas music, enjoying a hobby, or driving around the neighborhood to see the decorations and lights.

·        Simplify- Bigger and better means more work. Simplify what you can so you can spend more quality time with everyone. Schedule events around your loved one’s daily activities. Have everyone chip in to purchase a catered meal or do a potluck where everyone brings something. Consider gifting more efficiently, such as gift cards and shopping online.

If your loved one is experiencing memory issues, our FREE memory screening can help. The initial screening isn’t a diagnosis but rather a steppingstone. You can find out if the issues are typical age-related memory loss or if your loved one would benefit from a complete evaluation with their medical provider.

Don’t let your loved one go into the new year with unanswered questions about memory issues. Schedule your FREE memory screen here at Neuropsychiatric Research Center of Southwest Florida today! Call us at [phone], or request an appointment online.

Sources:

https://www.aarp.org/caregiving/life-balance/info-2018/holiday-stress-tips.html

https://www.fivestarseniorliving.com/blog/how-senior-caregivers-can-manage-stress-during-the-holidays-and-covid-19

[neuropysch]

Thankful for Alzheimer’s Research

Alzheimer’s disease (AD) was first described in 1906. Since then, numerous breakthroughs in technology, infrastructure, and disease knowledge have helped improve patients' lives and push us closer to a cure. Though the road is still very long ahead of us, November marks a time to pause and reflect on past, present, and future efforts. These are some of the reasons we are thankful for Alzheimer’s research.

Top Alzheimer’s Research Milestones

Below are some of the critical milestones that have taken place in Alzheimer’s research and a brief explanation of their significance.

·        1906- Dr. Alois Alzheimer first describes "a peculiar disease."

o   Dr. Alzheimer described a patient with profound memory loss, unfounded suspicions about her family, and other worsening psychological changes. He also saw dramatic shrinkage and abnormal deposits in and around nerve cells during her brain autopsy.

·        1968- Development of cognitive measurement scales

o   These were the first validated measurement scale for assessing cognitive and functional decline in older adults.

·        1980- Alzheimer’s Association Founded

o   Today, it is the leading voluntary health organization in Alzheimer’s care, support, and research.

·        1984- Beta-amyloid identified

o   They are a chief component of Alzheimer's brain plaques and a prime suspect in triggering nerve cell damage.

·        1986- Tau protein identified

o   Researchers discover that it is a crucial component of tangles and another prime suspect in nerve cell degeneration.

·        1987- First AD drug trial

o   Pfizer conducts clinical trials for tacrine, the first drug specifically targeting symptoms of Alzheimer's disease.

·        1993- First Alzheimer’s drug FDA approved

o   (FDA) approves tacrine (Cognex) as the first drug explicitly targeting Alzheimer's memory and thinking symptoms.

·        2004- Neuroimaging initiative

o   The initiative is a nationwide study to establish standards for obtaining and interpreting brain images. The ultimate goal is to identify high-risk individuals; provide early detection, and track and monitor disease-modifying medications' treatment effects.

·        2013-New genetic risk factors identified

o   During the collaboration of hundreds of research experts, 20 genetic variations were revealed to be associated with increased risk, 11 of which had not been linked with Alzheimer’s before.

·        2021- Aducanumab approved for the treatment of Alzheimer’s disease

o   Aducanumab is the first FDA-approved therapy to address the underlying biology of Alzheimer’s disease.

The Quest for the First Alzheimer’s Survivor     

Neuropsychiatric Research Center of Southwest Florida offers FREE memory screens for adults at risk of Alzheimer’s or concerned about memory issues they are experiencing. Our site also conducts research studies looking into potential new options for Alzheimer’s. Individuals with dementia, caregivers, and healthy volunteers are all needed to participate in upcoming research studies. To learn more, call us at [phone] or visit our website today!

Sources:

https://www.alz.org/alzheimers-dementia/research_progress/milestones

https://www.alzforum.org/timeline

https://www.biotechniques.com/neuroscience/neuroif_a-timeline-of-key-alzheimers-disease-milestones/

[neuropysch]

Cherishing Memories When Loved Ones Can’t

More than 16 million people in the U.S. are caring for someone with dementia as are countless others worldwide. Our memories are integral to our sense of self and our relationships. Therefore, watching a loved one lose their memories can be incredibly challenging and overwhelming. By learning what to expect and how to help them through the progression of dementia, you can carry on cherishing memories when your loved ones can’t.

Changes to Expect

Each individual’s journey through Alzheimer’s or other dementia is different. Nevertheless, there are three primary stages they progress through as symptoms become severe and limiting. Recognizing what stage your loved one is in can be helpful when care planning.

·        Early Stage: Many people at this stage may:

o   Ask repeated questions and have some problems expressing and understanding language.

o   Have mild coordination problems include having difficulty writing and using objects.

o   Experience depression, apathy, and mood swings.

o   Need reminders for daily activities and have difficulty driving.

·        Middle Stage: At this stage, most individuals likely cannot cover up their problems any longer. Symptoms include:

o   Increasingly more frequent memory loss, including forgetfulness about their personal history and inability to recognize friends and family.

o   Being more likely to become lost in familiar settings, experience sleep disturbances, and change mood and behavior.

o   Delusions, aggression, and uninhibited behavior happen more frequently.

o   Requiring structure, reminders, and assistance with the activities of daily living.

·        Late Stage: In this stage, most people are confused about the past and present. Your loved one may:

o   Lose the ability to remember, communicate, or process information.

o   May generally become incapacitated and immobile with severe to total loss of verbal skills

o   Become unable to care for themselves

o   Develop problems with swallowing, incontinence, and illness are also common

o   Also, experience severe problems with mood, behavior, hallucinations, and delirium.

o   Require around-the-clock care.

Helping Your Loved One

Even when your loved one seems to forget who you are, your role as a caregiver is vital to their health and quality of life. Don’t be afraid to ask for help from other family members and resources. More importantly, take care of yourself by giving yourself a break, getting enough sleep, and utilizing online and community support resources.

Your role as a caregiver will change with the progression of dementia. Early on, empowering them to seek treatment can have a profound impact on their response to them. Also, by involving them in future legal, financial, and healthcare planning, you can ensure their wishes are honored and play an active role in decision-making. Establishing a routine, creating a safe environment, and staying calm and patient help forms a strong foundation when caring for a loved one with dementia. More practical suggestions to consider can be found here.

If you or a loved one are experiencing memory issues, a FREE memory screening may be the starting point you need. To learn more about scheduling your FREE memory screen here at Neuropsychiatric Research Center of Southwest Florida, call us at [phone], or fill out a request form online.

Sources:

https://www.dementia.org/coping-with-dementia-patients-loss-of-memory

https://www.healthinaging.org/tools-and-tips/caregiver-guide-memory-problems

https://www.helpguide.org/articles/alzheimers-dementia-aging/tips-for-alzheimers-caregivers.htm#

[neuropysch]

Help Spread Awareness for Alzheimer’s

September is World Alzheimer’s Awareness Month. Alzheimer’s disease (AD) is the most common form of dementia, affecting about 6 percent of people 65 and older. Though it may seem like just a typical disease for older people, it is not a normal part of aging. Join us this September. Add your voice, help increase the volume, raise awareness, challenge stigma, and help spread awareness for Alzheimer’s.

Know the Signs.

Everyone will experience memory issues in their later years. Dementia is different and affects a person’s ability to do every tasks. Here are ten warning signs for dementia: 

They may remember events that took place years ago but not what they had for breakfast.

Conversing with a person with dementia can be difficult, and it may take longer than usual to conclude.

These changes are subtle at first and are better recognized by a loved one. Depression, for instance, is typical of early dementia. 

A person with symptoms could lose interest in hobbies or activities.

Tasks like balancing a checkbook or playing games that have a lot of rules become difficult.

Individuals with dementia can no longer remember faces, find the right words, or interact with people normally. Thus, deal with a lot of confusion.

Difficulty following storylines may occur due to early dementia.

The sense of direction and spatial orientation commonly starts to deteriorate with the onset of dementia.

The person may repeat stories, daily tasks such as shaving, or they may collect items obsessively.

They might crave routine and be afraid to try new experiences due to their challenges each day.

Get Involved Today!

There are many ways to get involved with World Alzheimer’s Month. This year’s theme is “Know Dementia. Know Alzheimer’s.” Share messages on social media, show others how to recognize the signs of dementia, raise or donate funds for research, or attend events and activities put on by your local Alzheimer’s association. No action is too small. Make sure you are using the hashtags of #KnowDementia and #KnowAlzheimers.

Research continues to move advances in detection methods and treatments for Alzheimer’s forward. The patients and healthy individuals volunteering in research studies make these advances possible. If you or a loved one is concerned about the memory issues currently being experienced, a FREE memory screen or our upcoming research studies may be an option. 

To schedule your FREE memory screen, or learn more about current and future Alzheimer’s studies, call us at [phone], or visit our website today!

 Sources:

https://www.alzint.org/get-involved/world-alzheimers-month/2021-theme/

https://nationaltoday.com/world-alzheimers-month/

https://www.healthline.com/health/dementia/early-warning-signs#when-to-see-a-doctor

[neuropysch]

Memory Loss: When Should I Be Concerned?

You may be worried about taking longer than before to learn new things, or how now and then you forget something important. When are memory issues age-related, and when should you be concerned? We have some general guidelines to help you sort it out.

Dementia is not Age-Related.

It's not uncommon that it gets harder to remember things on occasion as we age. However, genuine memory issues make it challenging to do everyday things like driving, talking on the phone, and finding your way home. Dementia includes the loss of cognitive functioning such as thinking, remembering, learning, and reasoning. Those with dementia may also have problems with language skills, visual perception, or paying attention, even personality changes. It interferes with a person's quality of life and daily activities. Memory loss, though common, is not the only sign of dementia. There are different forms of dementia, but Alzheimer's disease is the most common in people over age 65.

Signs you should talk with your doctor include:

Repeatedly asking the same question

Becoming mixed up in places, you typically know well

Difficulty following plans or instructions

Being more confused about time, businesses, and people

Inability to care for oneself such as bathing, eating, or unsafe behaviors

Why You Should Talk with Your Doctor

If you or a loved one are having memory issues, it’s time to talk with a specialist. Your provider can perform tests and evaluations that can help determine the cause. Memory loss and other thinking and reasoning issues have numerous potential causes besides Alzheimer’s or another dementia. These include brain injuries, depression, and medication side effects. In these cases, memory issues improve once the underlying cause is treated.

You can make the right treatment plan moving forward when you know the reason behind the memory issues. Individuals with memory issues should plan to check their memory annually per the National Institute on Aging. Neuropsychiatric Research Center of Southwest Florida offers FREE memory screens for adults concerned about their memory issues or at increased risk for Alzheimer’s. We also provide a chance to help advance medicine by enrolling in one of our upcoming studies. To learn more, call us at [phone], or visit our website.

Sources:

https://www.cedars-sinai.org/blog/concerned-about-memory-loss.html

https://www.nia.nih.gov/health/memory-forgetfulness-and-aging-whats-normal-and-whats-not

[neuropysch]

The Connection Between Diet and Memory Loss

Growing data supports the connection between diet and memory loss. Just like some foods have brain-boosting qualities, some also negatively affect them. We’re taking a deeper look into this connection and giving you the top foods to eat, including ones to avoid.

Diet and Memory Loss

A healthy brain relies on a steady flow of blood, oxygen, and other nutrients at all times. Anything that interferes with that process compromises thinking and memory, along with other more severe consequences. Vital nutrients are transported through blood vessels. Damage to these vessels or a blockage caused by cholesterol buildup can deprive the brain of oxygen-rich blood to function normally.

Diets high in saturated and trans fats are the number one cause of unhealthy cholesterol levels and buildup in blood vessels. In a recent study, a group of individuals who ate a high saturated fat diet performed worse on memory and thinking tests than a group that consumed the lowest levels of saturated fat. In addition, a gene variation associated with cholesterol levels is being studied that shows a greater risk of developing Alzheimer’s for individuals with this gene variation.

Best and Worst Foods for Your Brain

We can all agree that making better choices regarding what we consume is an excellent start towards better brain health. Here are some good and bad foods for brain health:

Best: These foods play a role in keeping your brain healthy. They also can improve specific mental tasks, such as memory and concentration.

Fatty fish

Coffee

Blueberries

Turmeric

Broccoli

Dark chocolate

Nuts

Worst: These foods have adverse effects on the brain, impact your memory and mood, and increase your risk of dementia.

Sugary drinks

Refined carbs

High processed foods

Aspartame

Alcohol

High mercury fish

 Get Your Memory Screened. For FREE!

Anyone can develop Alzheimer’s or another dementia. So, whether you’re at increased risk or concerned about memory issues, we can get you on the right path for answers. The Neuropsychiatric Research Center of Southwest Florida offers FREE memory screenings. This quick questionnaire can determine if you would benefit from a complete evaluation with your provider, though it is not a diagnosis. Call [phone] to schedule your free memory screening or request an appointment online today!

Sources:

https://www.healthline.com/nutrition/11-brain-foods

https://www.healthline.com/nutrition/worst-foods-for-your-brain

[neuropysch]

How to Honor Alzheimer's & Brain Awareness Month

Creativity and passion fuel Alzheimer’s and Brain Awareness Month, which takes place in June. Communities worldwide unite through various events and activities to raise funds and awareness for the care, support, and research efforts of the Alzheimer’s Association. Together, they fight the darkness of Alzheimer’s disease (AD), which globally affects 50 million people. Light up the dark and honor Alzheimer's & Brain Awareness Month by getting involved.

Alzheimer’s Isn’t Normal Aging.

Alzheimer’s-related memory changes are linked to aging, but it is not a normal part of aging. However, memory issues can be an early warning sign. This is because AD causes the damage and destruction of brain cells (neurons). When damaged, neurons lose connections to each other and eventually die. The damage starts most often in the brain region that controls memory, years before the first symptoms.

There are many ways to participate throughout June. Visit the social events page for more details on what your local community is doing to fight Alzheimer’s. In addition, you can celebrate Alzheimer's and Brain Awareness Month by wearing purple, researching the early signs, and more:

Show your support to the caregiver in your life by recognizing their     care needs or engaging in a kind gesture.

Share your own Alzheimer’s story, provide hope and support, and inspire people to join the fight.

Take 65 seconds of silence to recognize, in just over a minute’s time, a person’s life will change forever.

Join others across the world in raising funds and awareness on The Longest Day. You can start or join a fundraiser here.

Spread the word by using the hashtags #ENDALZ and #TheLongestDay on Instagram and Twitter. Change your Facebook profile picture to the Alzheimer’s Association frame to shine a light on the disease.

Honoring Brain Awareness with a FREE Memory Screen

Being proactive is vital in the early detection of Alzheimer’s or other dementia. Those currently experiencing memory issues and individuals with increased risk should have their brain health evaluated annually. Neuropsychiatric Research Center of Southwest Florida offers FREE memory screenings. The screening provides an insight into whether you would benefit from a complete evaluation.

It’s not a diagnosis but a very useful tool in determining the need for further evaluation and can track changes in the brain over time. So, honor Alzheimer's & Brain Awareness Month and love your brain by setting up your FREE memory screen TODAY! Call us at [phone] or submit your request online.

Sources:

https://www.americanhouse.com/blog/8-ways-honor-alzheimers-brain-awareness-month

 https://alz.org/abam/overview.asp

[neuropysch]

Staying Sharp into the Elder Years

Aging well is a goal of most Americans. They want to look young and feel young, even as they age. This desire fuels dermatology clinics, health clubs and plastic surgeons. Youthfulness of the body is coveted, but a youthful brain isn’t always on the forefront of the mind.

One key component of aging well is ensuring your memory stays sharp. A good memory that remembers vivid details, can quickly recall names, can make favorite foods without a recipe, and can help you feel young, even as you mature in age. Minor memory loss is a normal part of aging, but it can be difficult to determine if the memory loss should be a serious concern. Significant memory loss can be an indication of early-onset Alzheimer’s disease, another form of dementia or another health concern. 

Does Memory Loss Disrupt Daily Life?

Forgetting a name or phone number, but later remembering those details is normal. However, if you or your loved one find yourself constantly forgetting details that were recently learned – experiencing short-term memory loss – that can be a sign of something more serious. Begin paying attention to what types of details are often forgotten, and if these details are remembered later.

Familiar tasks such as driving to the grocery store or reheating food in the microwave should continue to be second nature, even as you age. If you or your loved one get lost going to the neighborhood grocery store or needing help using the microwave, it may be a concern to address with a doctor. Even as you age, memory loss should not disrupt daily life.

Is Memory Loss Changing Your Temperament?

As you age, your personality may shift in some areas. You will hopefully become more confident and self-assured. Your likes and dislikes may also change overtime. Becoming more suspicious, confused, experiencing increased irritability or anxiety may be an indication that something more serious is going on. If you or your loved one was once outgoing and social, but now wants to stay at home, withdrawing from friends and family, it may be worth speaking with a doctor.

What Should I Do?

It can be terrifying to admit that your memory isn’t what it once was. It can also be overwhelming to admit this about your loved one. Unfortunately, ignoring the concerns will not make them go away, and early intervention can help identify problems while there is still time to help. Keep track of trends as it relates to memory loss to discuss with your doctor.

Scheduling a free memory screening can also be helpful. A memory screen is a quick, simple test that evaluates your memory and other thinking skills. Memory screening can help detect health conditions, and help you age well. Neuropsychiatric Research Center of Southwest Florida provides free memory screening. To set an appointment, call us at [phone] or fill out an online form.

 Reference:

https://www.alz.org/alzheimers-dementia/10_signs

[neuropysch]

Beyond Sadness: A Deeper Look into Depression

Sadness is a feeling you get when you experience loss, complicated situations, and other disappointments in life. Everyone gets sad from time to time, but the feelings go away quickly, and you move on. Depression is a mood disorder that is often confused with sadness. However, depression doesn’t usually go away on its own and impacts every part of a person’s life. Depression goes beyond sadness, though it is one of the many emotions involved. Let’s take a deeper look into the lives of individuals dealing with depression.

Depression Overview

Depression is the most common mental health disorder in the U.S. Scientists and researchers believe the cause is the result of a combination of genetic, biological, environmental, and psychological factors. It is characterized by persistent depressed mood or loss of interest in things once enjoyed. Depression causes impairment in daily life. Without help, symptoms may last for a long time.

Symptoms:

irritability

fatigue

changes in sleeping or eating patterns

difficulty concentrating

feelings of deep, unwarranted guilt

physical symptoms, such as headaches or body aches without a specific cause

feelings of worthlessness

constant thoughts about death

suicidal thoughts or actions

The Catch-22 of Depression

Some people think depression involves a lack of willpower of individuals to “snap out of it.” Except, nothing is farther from the truth. Most people with depression would love nothing more than to be free of the feelings that drain their energy, hope, and drive every day. Things that may help ease symptoms like exercising and hanging out with friends seem impossible. The very nature of depression makes it difficult to get help.

Depression is treatable, but many benefit from support and understanding of loved ones in their treatment journeys. As a community, we can learn more about this condition and begin to replace assumptions with facts. Together, we can change the future of depression.  

Expanding Depression Options for Patients

Research efforts are underway to understand the causes of depression better and develop potential new ways for managing it. Clinical research studies and the volunteers who participate in them help evaluate the safety and effectiveness of these possible new options. Study volunteers not only help advance medicine but learn more about their condition, allowing them to prioritize their health better in the future.

To learn more about how you can get involved in upcoming depression research studies at the Neuropsychiatric Center of Southwest Florida, call us at [phone] or visit our website.  

References:

https://www.healthline.com/health/depression/depression-vs-sadness#risk-factors

https://www.psycom.net/living-with-depression

https://www.helpguide.org/articles/depression/coping-with-depression.htm

[neuropysch]

Depression Isn't a State of Mind.

Depression is one of the most treatable forms of mental health disorder. For instance, those who seek treatment will almost always get some symptom relief. Unfortunately, only around 1 in 5 who experience depression symptoms seek help. Depression isn’t a state of mind. It is a disorder most will experience at least once in their lives. We owe it to ourselves and future generations to change the stigma surrounding mental health disorder.

A Mental Health Disorder

Depression is a medical health disorder resulting from changes in the brain that affect how you think and act. It is an overwhelming feeling of sadness and hopelessness lasting longer than two weeks, called episodes. It also causes a loss of interest in doing the things you once loved, extreme lack of energy, sleep disturbances, agitation, suicidal thoughts, and other symptoms. Severity can range from mild to severe.

There is no known exact cause, though physical changes in the brain, hormones, and inherited traits are some of the factors we believe are involved. Over the years, research has shown that brain areas that regulate mood appear to function abnormally with this condition. It can affect anyone, regardless of gender, race, or family history. Children and teens can develop it too, and present different symptoms than adults.

The Treatment Kryptonite of Mental Health Disorder Stigma

Many tools can help manage symptoms of depression. Counseling, medications, and other therapies can be used in conjunction or alone. More often than not, a patient may have to try different ones before finding the right combination. In severe cases, hospitalization or residential therapy is necessary for a patient’s safety until their condition improves.

Depressed individuals face various symptoms that can make it harder to seek treatment. As with most illnesses, treatment helps ease symptoms and prevent them from getting worse. Nevertheless, misunderstandings, incorrect assumptions, and non-acceptance issues play a crucial role in why those affected don’t get help. While educating the public helps change some of the stigma surrounding depression, we must be persistent in our own fight for physical and emotional health.

There’s still a lot to learn about depression. The more we know, the better we can detect, prevent, and treat it. Clinical research studies are necessary to this process. The volunteers who participate in research make these advancements possible. To learn more about upcoming depression studies here at Neuropsychiatric Research Center of Southwest Florida, call [phone], or visit our website.

References:

https://www.mayoclinic.org/diseases-conditions/depression/diagnosis-treatment/drc-20356013

https://www.webmd.com/depression/ss/slideshow-depression-myths

[neuropysch]

Myths of Parkinson’s

Many misconceptions surround Parkinson’s Disease. Like many other conditions, these false truths can cause a delay in diagnosis and treatment, which can be devastating. Knowing the truth behind the myths of Parkinson’s can ultimately allow you to optimize your care so you can take better care of yourself.

The Facts Behind the Myths of Parkinson’s 

There are many myths about PD. Here are some of the most common:

Myth: PD only affects movement.

Fact: There are many non-movement symptoms of PD. These include impaired sense of smell, sleep disorders, cognitive signs, constipation, bladder symptoms, sweating, sexual dysfunction, fatigue, limb pain, tingling, lightheadedness, anxiety, and depression.

Myth: There isn’t much you can do for PD aside from medications.

Fact: Keeping active is one of the main things patients can do to remain active longer. Lower protein diets and gait therapy training are other ways to help with PD symptoms.

Myth: Some medications for PD cause symptoms to progress faster.

Fact: The misconceptions that PD drugs like Levodopa are toxic and progress symptoms faster were debunked a long time ago. It is a potent drug that improves symptoms of PD, but it is not toxic.

Myth: PD is fatal.

Fact: Parkinson’s Disease is not a death sentence and does not directly cause people to die. While the condition can put tremendous strain on the body, advances in treatments allow those with PD to have a near-average life expectancy.  

Clinical Research is Advancing Options for Parkinson’s Disease

Earlier this month, AC Immune, a Swiss-based company, announced it began clinical trials for the first-ever diagnostic test for Parkinson’s Disease. ACI-12589 is a next-generation PET imaging tracer that has shown significant potential to reliably detect and map deposits of pathological alpha-synuclein protein in the brain, which is the primary hallmark of PD.

ACI-12589 can enable accurate, potentially earlier diagnosis and disease progression monitoring in response to treatment effectiveness measurements in patients. This breakthrough is made possible by clinical research and their volunteers. Though exciting, more work needs to be done to continue improving the lives of those with PD.

To learn how you can get involved with upcoming research opportunities for Parkinson’s here at Neuropsychiatric Center of Southwest Florida, call (239) 939- 7777 or visit our website.

References:

https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease/myths-and-facts-7-parkinson-disease-misconceptions

https://www.parkinson.org/Understanding-Parkinsons/What-is-Parkinsons/Myths-about-Parkinsons

[neuropysch]

Gender Differences in Parkinson's Disease

Parkinson’s disease (PD) is a disorder of the nervous system that progressively affects movement. PD occurs in 50% more men than women, but that’s not the only variance. Gender differences in Parkinson’s disease also affect onset age, symptoms, treatment, and more.

2 to 1

Researchers don’t know why men are affected twice as likely with Parkinson’s disease than women. Early clinical study results indicate estrogen may protect women in the sense they have more dopamine available in key areas of the brain. Also, men have a higher rate of minor head trauma and exposure to toxins, but these theories need more investigation.

Onset and Symptoms of PD

Women tend to develop PD around 2.1 years later than men. In general, men and women experience the same motor and non-motor symptoms, but there are variances in which sex encounters more difficulty while diagnosed with PD. Some examples are:

Men physically act out more while dreaming than women.

Women experienced more tremor symptoms, and men had more rigidity issues.

Women develop motor symptoms later than men, so they score better at motor abilities.

Postural instability and lack of spatial awareness make women more susceptible to falls than men.

Men develop freezing of their walking gait much later than women.

Weight gain, fatigue, depression, restless legs, constipation are more common and more severe in women.

PD Treatment Effects by Gender

Levodopa is the standard medication to treat PD. Women metabolize it differently than men, so the dosage for men with PD is higher than for women. Their larger body mass could explain the higher dosage for men. Men also reported fewer side effects with levodopa, known as levodopa-induced dyskinesia (involuntary movements). Also, women receive surgical interventions less often than men do, and their symptoms are more severe by the time they get to that point. To add, the improvements gained from surgery may not be as significant for women.

Thanks to clinical research studies, more information about Parkinson’s disease is being discovered, such as the differences in disease progression in men and women. Undoubtedly, more work must be done so better ways to detect and manage it can be found for those diagnosed. To learn more about upcoming studies for Parkinson’s disease here at Neuropsychiatric Research Center of Southwest Florida, call [phone] or visit our website.

References:

https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055

https://parkinsonsdisease.net/men-affected-parkinsons/#:~:text=Researchers%20aren't%20yet%20sure,genes%20on%20the%20sex%20chromosomes.

https://www.healthline.com/health/parkinsons-symptoms-men-women#coping-with-pd

[neuropysch]

Pandemic, Presents, and Parkinson's

Caring for a loved one with Parkinson’s disease (PD) during the holidays can be a stressful time. A caregiver may feel pulled in multiple directions as holiday obligations add up on top of regular duties. The holiday spirit may seem lost amongst presents, cookies, and feelings of isolation. Find time for yourself, family traditions, and creating new memories despite the pandemic with a few simple tips.

Plan for Yourself, Plan for your Loved One

It’s easy to get overwhelmed during the holidays but planning ahead of time helps a lot. Spread errands around, toss aside guilty feelings, and ask for help. Create time each day for self-care and get enough sleep every night. Know and watch for the signs of burnout and consider implementing some of these helpful tips to make the season more enjoyable:

Gather with members of the same household only and consider a video call with other families to keep everyone safe.

If you have to travel, plan by calling the airline to request assistance services for patients with medical conditions. You can also find out about how medications and equipment should be stored and labeled. Give yourself extra time for rest breaks, arrival, etc.

Create a list of simple goals to keep expectations realistic and stress levels lower:

Communicate with family ahead of time regarding priorities and availability.

Try making the least number of changes in routine as possible.

Ensure you are well-supplied for the holidays so you can avoid last-minute trips.

COVID-19 and Parkinson’s

Patients with PD are mostly in their senior years, and older individuals are at the most risk for contracting COVID-19. The disease itself doesn’t raise your risk of getting COVID but makes it harder to recover if you get it. The CDC recommends you avoid travel and large gatherings this holiday season, particularly for those at higher risk, along with standard safety measures. Health officials are also strongly recommending seniors get the pneumonia and flu vaccine as soon as possible or speaking about it with their doctor.

Progress Through Research

Parkinson’s is a neurodegenerative disorder without a known cure. Through ongoing research efforts, breakthroughs in treatments have improved care continue to provide hope for the patients and their families. Some research areas focus on deep brain stimulation, neural growth factors, and various medications. Remarkable progress continues to take place, and yet we still have a ways to go.

Clinical research volunteers make improvements to healthcare possible. If you or a loved one has Parkinson’s, upcoming research studies may be an option. Take a stand today and learn more about future enrolling PD studies here at Neuropsychiatric Research Center of Southwest Florida. Call us at [phone] or visit our website.

References:

https://www.parkinson.org/understanding-parkinsons/covid-19

https://parkinsonpost.com/caregiver-tips-for-the-holidays/

https://www.parkinson.org/blog/tips/Navigating-the-Holidays

[neuropysch]

Caregivers Need Care Too

A family caregiver manages health emergencies, juggles appointments, and personal care of their loved ones. November is National Family Caregivers Month. This year’s theme is “Caregiving Around the Clock.” The essential role they play in others' health and well-being is the heart of why caregivers need care too.

Why Caregiving is Tough

A caregiver can be a spouse, partner, adult child, or another relative. In addition to caring for a loved one, they can hold full or part-time jobs, be responsible for their own families, and have other responsibilities. They are rarely trained, often unpaid, and on-call 24/7 for everything they are being asked to do, which includes:

Buying groceries, cooking, cleaning house, and doing laundry

Helping a loved one get dressed, take a shower, and with their medicine

Transfering someone out of bed/chair, helping with physical therapy, performing medical interventions—injections, feeding tubes, wound, and other treatments

Scheduling and driving to medical appointments

Talking with doctors, nurses, and other medical staff to understand what needs to be done

Handling finances and other legal matters

Being a companion

Taking Care of Yourself Too

Being a family caregiver doesn’t mean that you need to take care of someone else at the expense of your emotional, physical, and financial health. Taking care of yourself first means that you can be a better caregiver for your loved one. Caregiver.org has the following things to remember so you can take care of YOU too:

Eat right—good nutrition as opposed to stress-snacking. Limit alcohol      and other drugs

Exercise—it may be hard to find the time, but it’s the best cure for depression and increases your endorphins (“good” coping hormones)

Sleep—7-8 hours is hard to get but essential. Admit when you are experiencing burnout and get help

Providing care for a loved one is the most important role you will play in their lives. You are the gatekeeper that helps determine the quality of life during this time, particularly for those with Alzheimer’s and other dementias. The Neuropsychiatric Research Center of Southwest Florida is dedicated to finding effective treatments for those with Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD).

Early detection and advancing treatments are crucial for this disease and other conditions that affect us as we get older. To learn more about how you can get involved in our upcoming clinical research studies here at NPRC, call [phone], or visit our studies listing page.

References:

https://caregiveraction.org/resources/10-tips-family-caregivers

https://www.caregiver.org/caregiving-101-being-caregiver

https://nationaltoday.com/national-family-caregivers-month/

[neuropysch]

Benefits of Memory Screening

According to the CDC, as more people live long enough to be at greater risk of dementia, the prevalence of Alzheimer’s disease is estimated to quadruple by 2050. Health officials believe that the rise in numbers directly results from more people being diagnosed thanks to improved testing. Memory screens are an essential part of the testing process. They offer a first glance into any possible memory or thinking issues that may be the beginnings of Alzheimer’s disease (AD), other dementia, or even other health issues. Every person over 65 can benefit from a memory screen, and here’s why.

What is a Memory Screen?

Memory screens are quick, simple tests that evaluate your memory and other thinking skills. The test typically has questions to answer, tasks to perform, or both that take around 10 minutes to complete. The screen results will indicate whether or not the person would benefit from a full medical evaluation. Memory screens do not diagnose any particular illness and do not replace a consultation or full assessment with your physician.

Who Should be Screened?

If you are experiencing memory issues, are at risk for AD, or are over 65, you should be screened annually. Mild to moderate memory loss is expected as we get older, and it can be difficult to tell what is due to age and what is not. If your memory issues concern you in any way or are interfering with your daily life, you should still get checked out. Remember, anyone can develop AD. You don’t have to have a family history or other risk category to take control of your brain health.

Why are Memory Screens Beneficial?

Issues with memory and thinking are symptoms of other conditions besides AD, so it is crucial to identify the cause. Being made aware of memory issues can help rule out any underlying health condition which many see resolved symptoms once treated. Memory screens results can also be used as a baseline as you get checked annually to monitor any changes.

 If your screen results lead to a diagnosis of AD or other dementia, early intervention will allow you to play an active role in your care and life planning while you still can. You also have the opportunity to take advantage of therapies that may slow the changes made by Alzheimer’s or take part in research studies.

Free Memory Screens at NPRC

Here at NPRC, we understand the importance of early intervention for memory and cognitive issues. Our goal is to improve patients' healthcare with Alzheimer’s and other related memory disorders through clinical research studies we conduct. To set an appointment for your free memory screen, call us at [phone], or fill out our online form.

References:

https://www.green-hill.com/importance-memory-screenings-for-seniors/

https://alzfdn.org/about-afas-national-memory-screening-program/

https://www.homecareassistanceoshkosh.com/importance-of-memory-screening/

[neuropysch]

ALS: More Work to Do

French neurologist Jean-Martin Charcot discovered Amyotrophic Lateral Sclerosis ((a-my-o-TROE-fik LAT-ur-ul skluh-ROE-si) or ALS. Originally, ALS was known as Charcot’s disease after the discoverer. However, in June of 1941, it became known as Lou Gehrig’s disease when the hall of famer retired from baseball shortly after his diagnosis. There is no cure for ALS, leaving more work to be done to find effective treatments for this deadly condition. Continue reading to learn more about ALS and what research studies are doing to help.

What is ALS?

ALS affects the nerve cells in the brain and spinal cord, causing loss of muscle control. It is a progressive disease that begins with slurred speech, muscle twitching, and weakness in a limb. Over time, ALS affects the muscles that we need to eat, breathe, move, and speak. Typically, there is no pain at any stage, and the bladder and senses are not affected. ALS is fatal, and most live 3-5 years after diagnosis. However, some people live for ten or more years.

What the Ice Bucket Challenge did for ALS

Five years ago, the “Ice Bucket Challenge” swept the world and catapulted ALS funding for research to new heights. The funding surge has increased the pace of discovery, allowed the foundation to allocate more to researchers, and has paved the way for constructing one of the largest resources of ALS whole genome-sequencing data. Since then, five new genes connected to ALS have been found.

Treatments for ALS focus on symptom relief and slowing progression. Unfortunately, nothing can reverse the damage of the disease. While the FDA has two approved treatments for ALS, there is still work to do to find more effective therapies and, eventually, a cure. Clinical research studies have the responsibility of filling the large gap in the wake of ALS.

 If you or someone you love has been diagnosed with ALS,upcoming research studies may be an option. To learn more, visit our website.

Referrals:

https://www.als.org/understanding-als/lou-gehrig

https://www.als.org/stories-news/ice-bucket-challenge-dramatically-accelerated-fight-against-als

https://www.mayoclinic.org/diseases-conditions/amyotrophic-lateral-sclerosis/diagnosis-treatment/drc-20354027

[neuropysch]

COVID Summer Checklist for Caregivers

The risk for severe illness from COVID-19 increases with age, with older adults being the highest risk. Severe illness from COVID-19 may require hospitalization in intensive care, with a ventilator to help them breathe, or even loss of life. If you are a caretaker of an older adult, there are steps to take to keep yourself and loved one safe this summer should you need to venture out.

Getting Ready to Go

There is no way to ensure you have zero risks of infection; if we depend on others and include others in our lives, we can only be responsible for so much. As communities begin to open a little more as time goes on, you may want to enjoy some of the things you used to. Unfortunately, COVID-19 is still very prevalent, and with many areas all over enduring wave after wave of the rise in infections, you must always be vigilant in reducing your risk.

Plan ahead. Look into peak hours of visitation, and plan somewhere outside if possible. Find out if there are any restrictions regarding visitation numbers and designated hours, if people required to wear masks, etc. Groups from the same household do not need to stay 6 feet apart, but others need to keep a distance. Investigate what they are doing to sanitize in between groups and if the staff wearing personal protection equipment (PPE). Cancel plans if anyone in the group or you are sick.

What to Pack

Since the outdoors is the ideal area to commune, you will want to start with plenty of water to keep hydrated. Older people are more prone to heat stress illnesses such as heat stroke, so packing plenty of water, ensuring there will be adequate shade, and wearing loose, breathable clothing are some great starts.

Packing extra masks, in case yours becomes broken somehow, antibacterial wipes for the restrooms and seating areas and hand sanitizers of at least 60% alcohol should be on the list as well.

Stick to the Basics Outside

Social distancing rules and ways to reduce your risk have not changed since the onset of COVID-19. Here are some reminders when going out in public, or visiting family and friends:

Stay 6 feet apart from people not in your household

The longer you stay around someone, not in your home, the more your risks increase

Wear a mask, or cloth covering

Properly wash your hands

Don't touch your mask or face

Sanitize where there is no soap and water to wash your hands

Stay home if you feel sick

If you are looking to get out of the house and make a difference, consider participating in clinical research studies. Most clinic sites are keeping up with or exceeding CDC sanitation guidelines, and some offer virtual or phone visits as an alternative to face to face. To learn more about how you can get involved in the upcoming studies at The Neuropsychiatric Research Center of SW Florida, call [phone], or visit us here.

References:

https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/older-adults.html

https://caregiver.com/articles/heat-stress-elderly/

https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/deciding-to-go-out.html