EXACTLY.
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@nomexninja33
EXACTLY.
Import alliance bound
A$AP Rocky impersonates Tyler, the Creator
lmao it’s spot on
Don’t do it omg-humor.tumblr.com
Reblog this picture of me holding a Family Size box of Honey Nut Cheerios? I’d really appreciate it.
How can I say no to such a great photo and such a polite request?
i will always support this post
@mooserattler back on my dash!
Why isn’t this at a million notes, yet, Dante???
I’m not sure. Hey lovely people who have taken me over half way to a cool million! If you’d like to reblog again, I’d love that, if not, I still love you, and hope you’re having a great day. I’m gonna go do some stand up tonight.
I will always reblog this
You got it fam
Nessa one of the better looking Evo X’s imo
Video courtesy of ThatDudeinBlue
Operators are standing by.
My 2013 Mitsubishi Lancer Ralliart
My favorite ice cream flavor is nipple. What’s yours?
Addison’s Disease.
Addison’s disease is a rare but known disorder (John Fitzgerald Kennedy suffered from it) and it is also referred to as adrenal insufficiency. Adrenal insufficiency develops when adrenal glands do not produce enough of the hormone cortisol. This can happen due to a problem within the adrenals (called Addison’s disease or primary adrenal insufficiency) or due to a problem with ACTH, the signal the brain sends to the adrenals instructing them to make cortisol (called secondary adrenal insufficiency).
An important distinction for patients is that people with primary adrenal insufficiency (Addison’s disease) usually don’t make enough of the hormone aldosterone too; so in addition to taking cortisol replacement, they also need aldosterone replacement. Also, ACTH levels are elevated. People with secondary adrenal insufficiency are only low on cortisol.
Causes: Primary adrenal insufficiency - the outer layer of the adrenal glands is called the adrenal cortex. If the cortex is damaged, it may not be able to produce enough cortisol. A common cause of primary adrenal insufficiency is an autoimmune disease that causes the immune system to attack the adrenal gland(s). There are some very rare syndromes (several diseases that occur together) that can cause autoimmune adrenal insufficiency, such as Autoimmune Polyendocrine Syndrome (type 1 or type 2). Other causes include: amyloidosis; bleeding into the adrenal glands; cancer that spreads to the adrenal glands; infections (bacterial, fungal, tuberculosis) of the adrenal glands; surgical removal of the adrenal glands. Secondary adrenal insufficiency - it is caused by a lack of ACTH, made in the pituitary gland. By far the most common cause of this type of adrenal insufficiency is chronic steroid use.
Signs and symptoms:
Weakness
Fatigue
Abdominal pain
Nausea
Weight loss
Low blood pressure
Increased pigmentation of the skin, including areas not exposed to the sun (due to high levels of ACTH in primary adrenal insufficiency. This occurs because melanocyte-stimulating hormone (MSH) and ACTH share the same precursor molecule, pro-opiomelanocortin (POMC))
Salt craving (due to low levels of aldosterone in primary adrenal insufficiency)
Postural Hypotension
Depression
Treatment: it involves replacing the cortisol and/or aldosterone that the body is not able to produce, or that it secretes in an insufficient quantity. Cortisol is replaced with an oral synthetic glucocorticoid. The drug is taken one or two times each day. Aldosterone is replaced with an oral mineralcorticoid.