Happily ever after

I’ll be back to reconstruct this page

[putriariin]

Have Courage, and be Kind.

Cinderella (2015)

where there is Kindness, there is goodness. and where there is goodness, there is magic :)

[mindofapharmacystudent]

The discovery of a new antibiotic that could potentially aid in the fight against drug-resistant bacteria was covered on one of last night’s national news broadcasts, by major US newspapers, and by several online sources. Most sources touted the potential impact of the antibiotic, but pointed out...

[larstheyeti]

[theawkwardyeti]

[putriariin]

Haha GERD? :))

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[putriariin]

I'm not into social medias

They are just too noisy with so many notifications and people chit-chating here and there. Why dont people meet and talk to each other like old times?

But you are not one of them, aren't you, tumblr? what would i do without you :)

[putriariin]

Lack of understanding of basic scientific principles in biology and statistics and the absence of critical thinking about public health issues have led to rejection of medical science by a segment of the public and common tendency to assume that all adverse drug effect are the result of malpractice

Bertram G. Katzung, MD, PhD

I agree totally.

Di Indonesia, seringkali sedikit sedikit malpraktik. well, lets ask if you do have the understanding of basic scientific principles in biology or statistic or critical thinking about public health issues before accusing malpractice ;)

Ayo mulai biasakan bertanggungjawab terhadap pengobatan diri sendiri, silakan bertanya mengenai pengobatan yang kita dapatkan, bagaimana cara menggunakannya dan efek yang mungkin terjadi.

[lookbookdotnu]

Merry Christmas! (by Gabriela Grębska)

[mindofapharmacystudent]

The CDC has released its list of the 10 most challenging public health threats of 2014:

1. Ebola

2. Antibiotic resistance

3. Enterovirus D-68

4. Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV)

5. HIV/AIDS

6. Polio (with this caveat: “The world is on the brink of...

[mindofapharmacystudent]

The Los Angeles Times (12/20, Kaplan) “Science Now” blog asked, “What do real-world doctors have to say about the advice dispensed on ‘The Dr. Oz Show?’” According to a research published in the British Medical Journal, “less than one-third of it can be backed up by even modest medical...

[magicmedic]

[mynotes4usmle]

ANTIBIOTICS CHEAT SHEET :)

Also, REMEMBER!!!!

* Sulfonamides compete for albumin with:

Bilirrubin: given in 2°,3°T, high risk or indirect hyperBb and kernicterus in premies

Warfarin: increases toxicity: bleeding

* Beta-lactamase (penicinillase) Suceptible:

Natural Penicillins (G, V, F, K)

Aminopenicillins (Amoxicillin, Ampicillin)

Antipseudomonal Penicillins (Ticarcillin, Piperacillin)

* Beta-lactamase (penicinillase) Resistant:

Oxacillin, Nafcillin, Dicloxacillin

3°G, 4°G Cephalosporins

Carbapenems 

Monobactams

Beta-lactamase inhibitors

* Penicillins enhanced with:

Clavulanic acid & Sulbactam (both are suicide inhibitors, they inhibit beta-lactamase)

Aminoglycosides (against enterococcus and psedomonas)

* Aminoglycosides enhanced with Aztreonam

* Penicillins: renal clearance EXCEPT Oxacillin & Nafcillin (bile)

* Cephalosporines: renal clearance EXCEPT Cefoperazone & Cefrtriaxone (bile)

* Both inhibited by Probenecid during tubular secretion.

* 2°G Cephalosporines: none cross BBB except Cefuroxime

* 3°G Cephalosporines: all cross BBB except Cefoperazone bc is highly highly lipid soluble, so is protein bound in plasma, therefore it doesn’t cross BBB.

* Cephalosporines are ”LAME" bc they  do not cover this organisms 

L  isteria monocytogenes

A  typicals (Mycoplasma, Chlamydia)

M RSA (except Ceftaroline, 5°G)

E  nterococci

* Disulfiram-like effect: Cefotetan & Cefoperazone (mnemonic)

* Cefoperanzone: all the exceptions!!!

All 3°G cephalosporins cross the BBB except Cefoperazone.

All cephalosporins are renal cleared, except Cefoperazone.

Disulfiram-like effect

* Against Pseudomonas:

3°G Cef taz idime (taz taz taz taz)

4°G Cefepime, Cefpirome (not available in the USA)

Antipseudomonal penicillins

Aminoglycosides (synergy with beta-lactams)

Aztreonam (pseudomonal sepsis)

* Covers MRSA: Ceftaroline (rhymes w/ Caroline, Caroline the 5°G Ceph), Vancomycin, Daptomycin, Linezolid, Tigecycline.

* Covers VRSA: Linezolid, Dalfopristin/Quinupristin

* Aminoglycosides: decrease release of ACh in synapse and act as a Neuromuscular blocker, this is why it enhances effects of muscle relaxants.

* DEMECLOCYCLINE: tetracycline that’s not used as an AB, it is used as tx of SIADH to cause Nephrogenic Diabetes Insipidus (inhibits the V2 receptor in collecting ducts)

* Phototoxicity: Q ue S T  ion?

Q uinolones

Sulfonamides

T etracyclines

* p450 inhibitors: Cloramphenicol, Macrolides (except Azithromycin), Sulfonamides

* Macrolides SE: Motilin stimulation, QT prolongation, reversible deafness, eosinophilia, cholestatic hepatitis

* Bactericidal: beta-lactams (penicillins, cephalosporins, monobactams, carbapenems), aminoglycosides, fluorquinolones, metronidazole.

* Baceriostatic: tetracyclins, streptogramins, chloramphenicol, lincosamides, oxazolidonones, macrolides, sulfonamides, DHFR inhibitors.

* Pseudomembranous colitis: Ampicillin, Amoxicillin, Clindamycin, Lincomycin.

* QT prolongation: macrolides, sometimes fluoroquinolones

[kitadashi]

Hamster01 by sakato

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[lookbookdotnu]

Fairytale girl (by Ariadna Majewska)