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TRANS WOMEN: HERE'S SOME SHIT YOUR DOCTOR WONT TELL YOU ABOUT HRT

1. Progesterone: not for everyone, but for many people it may increase sex drive and WILL make your boobs bigger. Also effects mood in ways that many find positive (but some find negative). Most doctors won’t prescribe this to you unless you ask. Most trans girls I know swear by it.

2. Injectible estrogen: is more effective than pill or patch form. Get on it if you can bear needles bc you will see more effects more quickly.

3. Estradiol Cypionate: There is currently a shortage of injectible estradiol valerate. There is no shortage of estradiol cypionate. Functionally they do the same shit.

4. Bicalutamide: This is an anti-androgen that has almost none of the side-effects of spironolactone or finasteride. The girls I know who are on it are evangelical about it.

naidje-deactivated

@euryale-dreams

joyeuse-noelle

Are there HRT medications that don’t increase blood clot risk? I’m already at risk because of my blood pressure, and my doctor won’t prescribe HRT that increases clot risk while I’m on the medication - and I may never not be on the medication.

euryale-dreams-deactivated20201

Absolutely.

The concerns surrounding venous thromboembolic events as a side-effect of hormone replacement therapy can mostly be traced back to one particular study known as the Women’s Health Initiative. This study was an enormous undertaking which, unfortunately, demonstrated significant adverse effects of the hormone therapies studied. As a result of this the use of hormone replacement therapy in postmenopausal cis women was dramatically reduced as the medical community began to question whether or not the therapy caused more harm than good.

Naturally, trans women have been suffering from this fall-out ever since.

What physicians seem to fail to recognize is that the study examined a very specific hormone regimen which was, arguably, outmoded at the time the study was conducted: It examined the use of conjugated equine estrogen (Premarin) with or without the use of medroxyprogesterone acetate. Neither of these drugs is regularly used for the treatment of transgender women.

The estrogen most commonly used to treat transgender women nowadays is 17β-estradiol either in pill form or in the form of a sticky patch that you apply to your skin. Esters of estrogen (e.g. estradiol valerate) are also sometimes used either in a pill form or as an intramuscular injection.

Transdermal estradiol patches are the gold standard when it comes to treating women who are at high risk of a venous thromboembolic event. It simply does not increase the risk of developing a venous thromboembolism. The only thing you should keep in mind is that patches are not always well tolerated because of the lifestyle changes required to keep them from falling off and the fact that they tend to irritate the skin.

Fortunately, oral 17β-estradiol appears to be safe, regardless of the increased risk. At least one large study has shown that the use of oral estradiol in trans women is not associated with venous thromboembolic events. An individual woman’s risk would need to be substantial in order to contraindicate the use of oral estradiol.

For those who have significant risk of venous thromboembolism because they have had a previous thromboembolic event, because they are paralyzed, or because of some other factor it is good to know the relative risk between oral and transdermal estrogen. The latest research indicates that the use of transdermal estrogen lowers your risk of a thromboembolism to 80% of what your risk would be using oral estrogens.

It’s difficult to find hard numbers regarding the relative risk of venous thromboembolic events with regards to hypertension. The best I could find after an hour or so of searching was this study regarding VTE in lung cancer patients. Hypertension increased the risk by a factor of 1.8.

However, to put that into perspective being of African descent increases your relative risk for deep vein thrombosis by a factor of 1.3 when compared to Europeans. Europeans are, themselves, at increased risk when compared to Asians and Pacific Islanders by a considerable margin: a four-fold increase.

I should point out that being ‘male’ is also a risk factor for developing a thromboembolism and hormones are likely to be a contributing factor. Also, menopause is another serious risk factor. Given this information it is likely that the use of transdermal estradiol will lower your risk of thromboembolic events significantly.

As far as the anti-androgen is concerned: The primary use for spironolactone for cisgender people is as an antihypertensive.

Even if the risk of thromboembolism was truly significant with modern hormone replacement therapy it wouldn’t justify what your doctor is doing to you. The fact is that mortality in the transgender community from suicide–caused in part due to the lack of access to hormone therapy–is substantial. The quality of life lost when a trans woman is denied hormone therapy is substantial. The fact that your doctor does not appear to be taking this into consideration when they weigh the risk of thromboembolism against not receiving necessary medical care is deeply concerning.

I strongly recommend that you seek a doctor who is more sensitive to your medical needs as a transgender woman.

Edit: Fixed a minor, but embarrassing, error.

whatmountains

oh wow this is so helpful & good info

blackthorn-and-iron-deactivated

Everyone who cares about transfem people please reblog this

thetolerantleft-deactivated2017

this was really fucking helpful

blkwlw

I know a lot of trans women dont have acess to information like this and its very helpful.

blasting-the-bee-movie-script-d

It's with a heavy but hopeful heart that I watch Palestinian families fundraiser on here, slowly accumulating the precious little money to go around that they need to survive. However, not everyone is so lucky. A lot of Palestinians that have not had that kind of luck, that did not get early verification, that did not get massive platforms behind them from large bloggers, have approached me in my inbox, asking me kindly to do what I can for them. It kills me that I have so little to give myself, but I've seen this platform collectively raise enough to change someone's life. I've made a list of Palestinian fundraisers that are extremely low on funds, in the hope that drawing attention to people who have not been lucky at all can help turn that luck around. I know most of us can't possibly give enough to get all of these families safe in one go. But please, reblog this list. Pick one or two fundraisers, give what you can, and then keep track of it. Slowly, collectively, we can make a difference in these people's lives. Share and donate as much as you can. https://docs.google.com/document/d/178EGDFKkHlh3y4TMVX82kqgITHsqtoMdNccI2f_94Os/edit?usp=sharing

komsomolka

LOW ON FUNDS: Ahmed Halas fundraiser Maher fundraiser Mohammed Alwadiya fundraiser Mohammed Ayyad fundraiser Shady Samir Ashour fundraiser

!!!

guerrillatech

Black panther poster. Just as relevant today

sighsra

holic

palestinian-fundraising

Palestinian gofundme’s with zero donations as of May 11, 2024:

URGENT: Evacuate My Diabetic Kid Out of GAZA WAR

Help Abood Evacuate Gaza, Rebuild, and Pursue Education

Saving a dental student and his family from war

Family evacuation

Help me to complete my education

We are raising 6000$ to allow Razan to leave Gaza

Save Me, So I Can Live and Continue My Life Safely

Donate to help me and my family in Gaza

They helped Abdullah's family to escape the war on

Gaza Hope: Support Belal, Ameera & Baby Hala

Help Nada and her family to survive in Gaza

Help Ayah to pursuing her education

Help Leen get out of Gaza and get the treatment

Help Ahmed Mughani's brother & companion evacuate

Urgent Appeal for Maria's Medical Treatment

Helping me and my family.

Donte to save my mother from death in Gaza

Support Hadeel for education abroad

Evacuate young Dr Oday and family from Gaza

Help Support samah Family Evacuate from Gaza

Helping me and my family get out of Gaza

A Dream Deferred: A Student's Journey from Gaza

Support Aya's Family's Journey to Safety

help me and my family evacuate from death in Gaza

Support Youssef and Afnan's Medical Journey

Help Abdallah to continue his studies and dream

Support Jamil's Journey to Heart Surgery

HELP ABDALLAH AND HIS FAMILY EVACUATE FOR MEDICAL TR

Help Ahmed and Heba Breathe Easier in Gaza

Help me treat my father, my brother, and my family in Gaza.

Help Us Escape the Horrors of War and Save Zahra’s Life

Help Hadeel to Evacuate from Gaze & Resume her Dreams

Rebuilding Dreams : A medical student's in Gaza Genocide

Donate to support us to restore our home and our lives

Please help my father to receive treatment outside Gaza

Help my family to get out of Gaza

Help Maram and her daughter!

Help treat Jud and Fares after they were injured in the Gaza

I need urgent help for my son, Louay, who has autism.

Help me evacuate Gaza and treat my hand urgently

Help Mohammed and Doaa’s Family Find Safety

Help Darren's Family Survive in Rafah

Help my aunt Wala from gaza

Help Ali and Naema get out of Gaza

Help tariq's family survive the war in gaza

Help me, my children, and my wife to leave Goza

No Survival Without You : Help Malak,And Her Family Survive

Help for my children and family life

Urgent Support for Zainab and Mais's Medical Care fom Gaza

Help Israa leave Gaza and complete its treatment

Help Zain's family evacuate Gaza so he can get medical help

Help my family to get out of Gaza

Donate for peace to us

Help me to get out of Gaza & Back to my studies

Give Sami & his family a chance to get out of Gaza

Help Baraa's family get out of Gaza and not die

Overcoming Obstacles: From Gaza to Education

Help saja to get out of gaza

Evacuate Hamoudy from Gaza for medical treatment!

Help my family escape Gaza and receive Medical aid

Help My Family In Gaza

sscarletvenus

i do not pity israel. never have, and never will.

each night that gaza experiences is deadlier than the last, as idf soldiers record propaganda tiktoks, make rave parties and grwms and fit checks, gloat over having food and water, and film themselves deriving sadistic pleasure from torturing their hostages and victims and desecrating the dead.

Palestinians have to display their martyred before the camera for you to believe the atrocities that the zionist entity has subjected them to. they cannot even mourn in private. the apartheid entity murders them in cold blood, and you deliver the killing blow by doubting them.

babies whose families have been killed will never get to know their own name.

i can't reshare a tenth of the videos and photos that cross my timeline. i have seen more dead children in the past month than i have known death my entire life.

israeli settlers burn olive trees, bomb bakeries and fishing boats, shower white phosphorus and earthquake bombs on the captive civilians of gaza. you already know about the disastrous effects of white phosphorus, but earthquake bombs were last used during ww2 to wipe out entire cities.

how holy is the land that seeks to be built over the mass graves of thousands of children? is it holier than the miracle of a child being born in this hypocritical world?

all 11 universities in gaza have been bombed. academics should be agitating right now, especially those who call themselves "decolonial thinkers." destruction of universities is a sinisterly deliberate act to sabotage the Palestinians who will survive this great catastrophe.

the act of cleansing your hands before prayer is extremely important to muslims. no part of us can remotely comprehend the grief of the mother who refused to wash her hands from the blood of her children after losing them in a zionist airstrike over gaza. "I swear I won't wash them, I won't wash my hands, how else am I supposed to sleep near my kids."

it is only both moral and right when one side defends itself. the other side are the price of war, no better than insects and cattle and sheep left to die within the four walls of the slaughterhouse.

this situation should not be up for debate, but let me finish with one final thing : do your research about Palestine. HOWEVER. you do not need a degree in middle east studies to object to an ongoing genocide. if someone outwits you in a debate about historical details and every nuance of a subject, you were and will remain entirely correct in objecting to a genocide.

may those martyred rest in peace and be reunited again with their loved ones in heaven's eternal vastness.

DO NOT STOP TALKING ABOUT PALESTINE.

glory to Palestinian resistance. from the river to the sea, Palestine will be free.

5centsapound

More excerpts from the extremely beautiful “Subjective Atlas of Palestine“ project. View the full publication via link.

About: The Dutch designer Annelys de Vet invited Palestinian artists, photographers and designers to map their country as they see it. Given their closeness to the subject, this has resulted in unconventional, very human impressions of the landscape and the architecture, the cuisine, the music and the poetry of thought and expression. The drawings, photographs, maps and narratives made for this atlas reveal individual life experiences, from preparing chickpeas to a manual on water pipe smoking, from historic dress to modern music. Pages containing humorous and caustic newspaper cartoons and invented Palestinian currency followed by colourful cultural diaries and moving letters from prisoners. All in all, the contributions give an entirely different angle on a nation in occupied territory. In this subjective atlas it is the Palestinians themselves who show the disarming reverse side of the black-and-white image generally resorted to by the media.

ot3

that link is dead so here’s an updated one

manga-and-stuff

Artbook collection Master-post

Dorohedoro MUD AND SLUDGE + Dorohedoro Sketch Book 'Day Dream Hour' Artbooks 1-5 by Ryōko Kui (Dungeon Meshi) AKIRA Club

Witch Hat Atelier Special Edition Volume 02 + 06 Artbooks Yokohama Kaidashi Kikou - Book of Paintings + Postcard Book "BLAME! and so on" Artbook

The Art of Nausicaä of the Valley of the Wind Miyazaki Moebius exhibition catalog The Art of Moebius

"Der Mond" Neon Genesis Evangelion Artbook "EYES ONLY" SPY×FAMILY Official Fanbook The Art of Fullmetal Alchemist 1 + 2

Elden Ring Art Book Volume 1 + 2 Dark Souls 1-3 Design Works Bloodborne Official Artworks

SEKIRO - SHADOWS DIE TWICE Official Artworks Grimoire Nier + NieR Art – Kazuma Koda Art Collection

The art of Alice Madness Returns SCORN The art of the Game The FLCL Archives

The Art of Metal Gear Solid I - IV - Gallery Works and Studio Works Spider-Man Into the Spider-Verse -The Art of the Movie Spider-Man Across the Spider-Verse The Art of the Movie

The Artwork of Berserk Alphonse Mucha's "Figures Decoratives"

Here's a link to the entire collection, in case any of the individual links are broken.

This post will also be edited as more Artbooks are added, check this link for the up-to-date version.

ctntduoarchive

wait till the tumblr girlies find out that in binary star systems sometimes one star will basically eat the other and kill them both - resulting in the most powerful thing a star could ever do in its life.

ctntduoarchive

you can become the greatest reckoning in the world but it will cost you your life and your partner’s life. or do you wish to simply circuit each other until you both die - never truly touching

ctntduoarchive

thekimonogallery

“Festival Horse”, by Japanese illustrator Tatsumi Hashimoto. Niigata Prefectural Museum of Modern Art

water2

it’s easier than you think

(full zine)

addersmire-moved

A CRUEL THING

a riso zine i made by collaging work from alan lee’s lord of the rings sketchbook. the text was created by starting each sentence with 2-3 words and then selecting options from my phone’s predictive text to complete the sentence.

physical zines • read SLAIN IN HIS HONOR • read A CRUEL THING