Built from the bottom up, synthetic cells and other creations are starting to come together and could soon test the boundaries of life.


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Built from the bottom up, synthetic cells and other creations are starting to come together and could soon test the boundaries of life.
Popular Science: Researchers Make Artificial Cells That Can Replicate Themselves.
Scientists create basic artificial cell from silicon that "can produce proteins from DNA"
By Courtney Humphries - The system, though relatively simple, suggests a path to mimicking life with partly manufactured components, says Roy Bar-Ziv, a materials scientist at the Weizmann Institute of Science in Israel, who is leading the work. Cells constantly create proteins from instructions coded in DNA sequences. How much of each protein is made is controlled by other genes, often in complicated feedback loops. Bar-Ziv calls his cell-on-a-chip “a new system allowing us to examine how genes are turned on and off outside the living cell.” READ MORE ON MIT TECHNOLOGY REVIEW
Weizmann Institute team reports on its groundbreaking cell-on-a-chip that fulfills a longstanding dream of mimicking the dynamics of a living cell.
Years of intense lab work in Israel have led to the world’s first artificial cell-on-a-chip, an exciting development with many potential applications.
“The idea to mimic a living cell is a longstanding dream shared by many,” Weizmann Institute of Science Prof. Roy Bar-Ziv tells ISRAEL21c. “If we can build a primitive model of something so complex, we can possibly understand the dynamics of protein synthesis better.”
Bar-Ziv began this project as independent researcher after his post-doc at Rockefeller University in New York 12 years ago. “It took that long to get it to work,” the physicist says.
Read More: Israel21c
10 Medical Technologies That Could Shape The Future
10 Medical Technologies That Could Shape The Future
It goes without saying that our society is moving faster than it ever has in the past. As medical technology surges forward with unprecedented speed and accuracy, many of us are left in the ensuing dust storm of obsolete procedures that were commonplace mere decades ago. But if we look up and gaze into the near future, we can see the beginnings of a whole new world of medical treatments that the…
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The title is a little hyperbolic, but we are thrillingly close to making this actually work.
Towards a Minimal Cell A Gallery of Giant Liposomes by Jorge Bernardino de la Serna University of Southern Denmark
One of the most ambitious endeavors of synthetic biology is creating "minimal cells" that fully recapitulate the functions of a natural cell—they capture energy, maintain ion gradients, store information, and mutate.
Although such technologies are still far on the horizon, researchers have made great progress in creating "semi-synthetic cells" that can mimic specific cellular tasks, such as protein production and synthesis of lipid membranes.
Many of these artificial cells reside inside liposomes, artificial vesicles each comprised of a lipid bilayer.
Technical Details Each micrograph shows a giant liposome ~20-50µm in diameter comprised of fats and proteins from the surface of the mammalian lung alveoli without any chemical treatment. The liposomes are directly isolated from a lung lavage.
Each micrograph was acquired at a different temperature or has varying composition of native fats and proteins.
Images obtained with a Laser Scanning Confocal inverted microscope with either conventional fluorescent excitation or two-photon excitation.
Source: Cell