Filoviruses get their name from the Latin word "filum," meaning thread—a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.
One reason these viruses remain so deadly is the instability of their surface proteins, which makes them difficult for our immune systems to detect and challenging for researchers to target with treatments or vaccines.
A Nature Communications study from Scripps Research scientists, describes new vaccine candidates designed to protect against multiple filovirus strains.