#eleutherococcus

[jillraggett]

Plant of the Day

Monday 25 September 2017

The unusual deciduous shrub Eleutherococcus leucorrhizus var. leucorrhizus is a native of China and was introduced by Ernest Wilson in 1901. As a member of the Araliaceae family it is autumn flowering providing nectar and fruit for wildlife late in the season.

Jill Raggett

[botanica-andina]

🌿 Eleutherococcus senticosus (Eleutherococcus)

Eleutherococcus senticosus: Araliaceae family.

Yerbateca.org botanical encyclopedia with PubMed citations

[siglerprescriptiondrugcards]

Eleutherococcus

Scientific Names: Eleutherococcus senticosus, (synonyms: Acanthopanax senticosus, Herdera senticosa) Other Common Names: Siberian or thorny ginseng, eleuthero, Taiga root, thorny Ussurian pepperbush, devil’s shrub, wild pepper, touch-me-not Overall Safety: 😐

Therapeutic Efficacy and Considerations:

Athletic Performance: 🙁 Results of studies examining effects on muscle strength and aerobic performance have been contradictory. Only one very small study found any benefit on oxygen uptake or recovery time and only small increases in strength in some of the muscle groups tested. Two other trials found no difference from placebo on any outcomes. Evidence does not support use of eleutherococcus for athletic performance.

Stress Adaptation: 😐 One trial, using an unknown amount and type of eleutherococcus extract demonstrated some improvements in cardiovascular responses to stress in a laboratory-based stress-inducing exercise. More research is warranted, but until more is known about clinically significant effects, as well as effective dose and formulation, eleutherococcus cannot be recommended for this indication.

Herpes Simplex II: 😐 One trial has compared an eleutherococcus root extract to placebo for the prevention of recurrent Herpes simplex II infections and noted a decrease in the frequency of outbreaks and the severity of symptoms. Some major methodological considerations limit confidence in the results. More research is warranted, but the current evidence is not sufficient to recommend eleutherococcus for this indication.

Chronic Fatigue: 😐 One trial compared a standardized powered extract eleutherococcus to placebo for treatment of chronic fatigue; no significant improvement over placebo was seen. There was a statistically significant improvement from baseline in patients with moderate fatigue, so further research may be warranted. However, current evidence does not support the use of eleutherococcus in managing chronic fatigue.

Chemistry/Pharmacology: The primary components of eleutherococcus are multiple eleutherosides, which actually are several different types of chemicals such as beta-sitosterol and other sterols, saponins, lignans, coumarins, and others. Eleutherosides B and E are the most abundant and are standard marker compounds in products. Individually, the components have many opposing effects. The whole root or whole root extracts can have variable effects such as hyper- and hypotension, CNS stimulation, and sedation, or hyper- o and hypoglycemia (a predominance of hyperglycemia was seen in one study). Effects that predominate may be dependent on the individual’s underlying status, which fits with eleutherococcus’ traditional use as an adaptogen – a substance that helps to” normalize” both under-active and over-active body functions. Binding to estrogen receptors occurs, and there may be binding to glucocorticoid, mineralocorticoid, and progestin receptors to a lesser extent. Immunological effects include stimulation of macrophages, T-lymphocyte proliferation, and activation of T-cells and killer cells. Other proposed actions for certain constituents include antioxidant, anticancer effects, ultraviolet light protection, inhibition of platelet aggregation, antihistamine, anti-inflammatory, and diuretic actions. Because so many studies have provided conflicting results, it cannot be said that any activities are well-characterized.

Drug Interactions: Anticoagulants/antiplatelet agents (due to increased risk of bleeding), digoxin (due to possible increased levels), hexobarbital (inhibited metabolism, avoid concomitant use), stimulants such as caffeine, ephedra, or others (due to increased HTN and CNS stimulation), vitamins B1, B2, and C (increased excretion, avoid concomitant use), EtOH, CNS depressants, and hypoglycemic agents (due to possible increased effects). Substrates of cytochrome P4501A2, 2C9, 3A4, and 2D6 (due to possible enzyme inhibition), although at recommended doses does not appear to inhibit or induce cytochrome P4503A4 or P4502D6. May increase the actions of kanamycin.

Contraindications/Precautions: Pregnancy/lactation/children (due to unknown effects), cardiovascular disorders and hypertension (due to cardiovascular stimulatory effects), hormone-sensitive cancers (due to estrogenic effects). May exacerbate mania and schizophrenia so generally avoided in these patients. Use for longer than three weeks is not recommended, but it has been used safely for up to two months.

Adverse Effects: Generally well tolerated; reported effects include decreased coagulation, hypertension, tachycardia, diarrhea, euphoria, agitation, decreased concentration, dizziness, anxiety, insomnia, slight drowsiness, restlessness, rash, estrogenic effects (breast pain and vaginal bleeding). Long term use can lead to an inflamed sciatic nerve causing muscle spasms.

[medicine-art]

Extract of Eleutherococcus from wrinkles, acne , diabetes and baldness

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In the neuroses, diabetes and as a tonic for hypotension, fatigue, exhaustion: Pharmacy 25-50 drops of the extract 2 times a day half an hour before meals the course of 30 days.

With hair loss, to stimulate hair growth, for dandruff massage into the hair roots extract Eleutherococcus before every hair wash for half an hour.

To accelerate the healing of wounds and regeneration of tissue in skin diseases the intake of 15-20 drops 20-30 minutes before meals 3 times a day, as well as lotions of a solution of extract of Eleutherococcus (1 teaspoon on 0,5 glasses of water).

For oily acne prone skin to use instead of tonic solution of Siberian ginseng extract 5 drops to 1 tablespoon of water or hydrolate of green tea. Heals wounds, reduces inflammation, regulates sebum secretion of the skin.

To reduce the number of wrinkles is a drop of extract add in cream and apply on the skin. Use daily. You can make a mask from any of the foundations with the addition of a couple of drops of fluid extract of Eleutherococcus on one application. To do this mask 1 time a week. Gradually wrinkles are smoothed and the skin is tightened, adjusts the shape of the face.

[medicine-art]

The benefits of Eleutherococcus

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Siberian ginseng is rich in vitamin C and b vitamins, and many trace elements. The healing properties of plants are determined by a special group of chemicals called eleutherosides.

Tonic and stimulating effects of drugs of Eleutherococcus characterized by an increase of hemoglobin in the blood, physical strength, muscle mass and lung capacity.

Siberian ginseng has good recovery properties, therefore its use in medicine in the postoperative period helps accelerate the healing of tissues and help restore the protein composition of the plasma. You can buy it at any pharmacy.

* Pharmacy Eleutherococcus extract take before lunch 20 drops 2 times a day as anti-toxic agent.

* For irritability, fatigue, apathy Siberian ginseng drink twice a day before meals to 30 drops.

* Vegetative-vascular dystonia take 30 drops before meals in the morning 3 times a day. The course is 2 weeks.

* In rheumatic lesions of the heart, take 2-3 times a day 20 drops. It stimulates the heart.

* In case of mental fatigue extract twice or thrice per day in their pre-dinner time 20 drops.

* As a General tonic doobedennoe time 2-3 times a day 15 drops, can be added to juices or tea.

* Siberian ginseng helps to increase the potency, so it is very useful for the stronger sex. To do this, take 20 drops pharmacy of the drug 2-3 times a day in morning time.

* Women in the postpartum period to restore strength is recommended 2 times a day 20 drops. Not to take at night.

* In cases of severe manifestations of menopause - 30 minutes before food in morning time by 25-40 drops. Course from 25 to 30 days.

[botanicsstories]

A neglected genus

Eleutherococcus leucorrhizus is a sparsely spined, deciduous shrub that is growing from a turn of the 20th Century Wilson collection. Native to SW China where it grows in mixed woodland.

The terminal inflorescence is a paniculate umbel; often several auxiliary umbels are present surrounding this. These open later, if at all, than the main terminal cluster exhibiting their protruding white anthers, through magnification the slight rigid lime green stigma.

In the Chinese plant collection there is a much darker leaved variety E.l. var. setchuensis, in fruit. The individual berries splay out architecturally on individual stalks and darken deep purple. These are long lasting through the months into winter.

Eleutherococcus leucorrhizus

Eleutherococcus leucorrhizus

Eleutherococcus leuchorizus var. setchuensis

Eleutherococcus leucorrhizus, twig

A neglected genus was originally published on Botanics Stories