Around the turn of the 20th century, forensic firearm examination was neither systematic nor reliable, and many of the experts called to testify were self-proclaimed and questionable at best. Goddard, a retired Army physician and gun enthusiast, helped to change the situation. As a physician, he had risen to directorship of The Johns Hopkins Hospital in Baltimore, Maryland. In 1925, he joined the Bureau of Forensic Ballistics, a private organization, and worked on several famous cases. As a result of his growing reputation, Goddard was called to examine evidence of the infamous St. Valentine’s Day Massacre in Chicago in 1929. He was able to show that all of the victims had been killed by two Thompson submachine guns. Some of the jurors in that case later raised money to establish a forensic laboratory at Northwestern University in Evanston, Illinois, called the Scientific Crime Detection Laboratory. Goddard was appointed as the first director of the laboratory and stayed until 1932. The laboratory moved to Chicago and became the Chicago Police Department laboratory in 1938.
Goddard also assisted the FBI in establishing firearms analysis capability at their new lab, inaugurated in 1932. Some of the tools used in modern firearms examination were developed by Goddard and co-workers.