#liver damage

[toothfairyinc]

i've been sleeping so fucking much whats going on

i wonder if this is related to the liver damage at all or if i'm just an eepy guy

[sexy4ever]

is this aesthetic?

[oldcoyote]

so the bad news is, my liver is just about packing it in!!

long story short, the combination of medications i'm taking for my autoimmune conditions (methotrexate and leflunomide) apparently have a high risk of liver damage as a side effect. my doctors knew this and decided it was worth the risk, and naturally with my luck this is where i wound up

so i am currently off all my medications to help my liver recover and stuck on bedrest for two (2!!!) weeks which is going to be literal torture for someone like me who has a full blown identity crisis every time she's not being productive enough. not only am i in pretty serious discomfort and pain right now from the liver damage, but my pain is going to get significantly worse over the weeks to come as i'm not allowed to take the two drugs that manage my chronic pain the most (listed above) nor am i allowed to take the majority of painkillers because hey guess which organ they fuck with? just take a WILD guess

that said my main concern right now is not the pain and discomfort bc i can handle those, but the affect this is going to have on my mental health while i'm not able to get things done or be actively productive day to day. i realized recently that i don't know how to relax anymore, i don't know how to sit and just enjoy myself watching stuff or reading or playing games. i have lists of all of those things - movies and tv shows and concerts i want to watch, piles of books and a huge folder of fanfics i want to read, and so many video games i want to try. but the problem is i can't do any of those things without feeling horribly guilty about wasting valuable time? i'm so stressed while trying to enjoy myself that i don't enjoy any of it, and can barely pay attention

if anybody has any advice on how to overcome this issue or what i can do to re-train my brain to relax, please help. i am at a complete loss and looking down the barrel of two incredibly miserable weeks made much worse by this problem

[bpod-bpod]

Scar Over?

The Chinese liver fluke is a flatworm found in freshwater environments. Around 15 million people in East Asia are currently infected by this parasite, often due to eating undercooked fish. Setting up camp in the bile ducts, the flatworm feeds on bile and causes liver scarring and cancer – although we don't understand exactly how. Here in cross-section we see two parasitic worms (white) surrounded by the scarred bile duct tissue (purple) of a mouse. Scientists developed genetically modified mice that capture the features of human disease when infected by the flatworm. Using these mice, they discovered that the Chinese liver fluke releases molecules that activate the immune system and cause inflammation. This rallies cells called myofibroblasts to the infection site, where they trigger scarring. This new understanding could help researchers develop more effective treatments for Chinese liver fluke infections and even ways to prevent the long-term damage they cause.

Written by Henry Stennett

Image from Key Laboratory of Zoonosis Research, Ministry of Education; College of Veterinary Medicine, Jilin University, Changchun, China

Research by Yuru Wang, Xu Zhang and Xiaocen Wang et al, Key Laboratory of Zoonosis Research

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Neglected Tropical Diseases, January 2023

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[eloquentlyunscathed]

Liver Surgery, organized by Brent Conway

Hi, my name is Brent and I’m trying to raise money to help pay for my cats Liver Surgery. It mean the worl… Brent Conway needs your support

I am raising money for the other half of my cats Liver surgery. Any amount will help. I love him so much.

[findthatpicrew]

五百式カクテルメーカー

ショートカクテルが作れます。描き足しや加工可。 【加工について】 メーカーで作った画像に加筆・着色などした際は『必ず』そのことを明記して下さい。自作であると誤認させたり、画像メーカーだけで作ったと誤認させることの無いようお願いします。 ✕「自分で描いた」 ✕「五百式カクテルメー

[sleepwithmonsters]

This is my favorite kind of joke

[mollydollyjournals]

Day 10/28 - Wednesday 18th November - 156.4lbs

I feel a little better today. Physically horrible, but mentally reset. I definitely needed that drink yesterday. I hate that but it is what it is. I don't know how dehydrated I am so I don't know how seriously I can take today's weight... we'll see I guess.

I have exactly 60 seconds to finish my coffee, brush my teeth, wash my face, put on some outside clothes and get going to my appointment so I kinda need to move my ass and I guess I'll come back and ramble more later...