This study uses human mesenchymal (the embryonic origin of connective tissue) cell lines (immortal and unlimited lab-grown cells) as a surrogate supply of extracellular matrix – the molecules outside cells but influential in their functions and behaviour. Customising these cells by CRISPR/Cas9 gene editing reveals biochemical components of the matrix that are important in bone tissue repair
Read the published research article here
Image from work by Sujeethkumar Prithiviraj and colleagues
Cell, Tissue & Organ Engineering Laboratory, Department of Clinical Sciences, Lund Stem Cell Centre, Lund University, Lund, Sweden
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in eLife (reviewed preprint), January 2025
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