#nih image gallery

[frontal-cortex]

Hematopoietic Cells by NIH Image Gallery Via Flickr: Confocal image showing the accumulation of myeloid hematopoietic cells throughout the mesenteric adipose tissue. Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health

[frontal-cortex]

Mouse retina by NIH Image Gallery Via Flickr: What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. The image is from a research project investigating the promise of gene therapy for glaucoma. It was created at an NIGMS-funded advanced microscopy facility that develops technology for imaging across many scales, from whole organisms to cells to individual molecules. The ability to obtain high-resolution imaging of tissue as large as whole mouse retinas was made possible by a technique called large-scale mosaic confocal microscopy, which was pioneered by the NIGMS-funded National Center for Microscopy and Imaging Research. The technique is similar to Google Earth in that it computationally stitches together many small, high-resolution images. More details: images.nigms.nih.gov/Pages/DetailPage.aspx?imageID=3697 Credit: Kenyoung Kim, Wonkyu Ju and Mark Ellisman, National Center for Microscopy and Imaging Research, University of California, San Diego NIH funding from: National Institute of General Medical Sciences (NIGMS)

[whipplewhopper]

3D image of actin in a cell by NIH Image Gallery Via Flickr: Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Here, researchers have used a technique called stochastic optical reconstruction microscopy (STORM) to visualize the actin network in a cell in three dimensions. The actin strands were labeled with a dye called Alexa Fluor 647-phalloidin. This image appears in a study published by Nature Methods, which reports how researchers use STORM to visualize the cytoskeleton. Credit: Xiaowei Zhuang, HHMI, Harvard University, and Nature Publishing Group NIH support from: National Institute of General Medical Sciences

[gmartinezmolina]

Ebola virus Makona por NIH Image Gallery Por Flickr: Scanning electron micrograph of Ebola virus Makona (in red) from the West African epidemic shown on the surface of Vero cells (blue). Early during the recent Ebola epidemic in West Africa, scientists speculated that the genetic diversity of the circulating Makona strain of virus (EBOV-Makona) would result in more severe disease and more transmissibility than prior strains. However, using two different animal models, National Institutes of Health scientists have determined that certain mutations stabilized early during the epidemic and did not alter Ebola disease presentation or outcome. More info: www.nih.gov/news-events/news-releases/despite-mutations-m... Credit: National Institute of Allergy and Infectious Diseases, NIH

[gmartinezmolina]

Type II Neurons in the Mouse Cochlea por NIH Image Gallery Por Flickr: Type II neurons (green) in the mouse cochlea contact many hair cells, but make up only a small fraction of the neurons in the auditory nerve—the nerve that sends sound information from the ear to the brain. Scientists are just beginning to study the role of Type II neurons in hearing. Credit: Pankhuri Vyas, Ph.D., and Jingjing Sherry Wu, Ph.D., The Johns Hopkins University School of Medicine NIH support from: National Institute on Deafness and Other Communication Disorders

[gmartinezmolina]

Interwoven Muscle Fibers por NIH Image Gallery Por Flickr: Interwoven muscle fibers of a rat’s tongue. This intricate muscular anatomy allows for the complex tongue movements necessary for vocalizations and swallowing. Credit: Miranda Cullins, Ph.D., University of Wisconsin, Madison NIH support from: National Institute on Deafness and Other Communication Disorders

[gmartinezmolina]

Staphylococcus aureus and white blood cells por NIH Image Gallery Por Flickr: Scanning electron micrograph of S. aureus bacteria escaping destruction by human white blood cells. According to the Centers for Disease Control and Prevention, Staphylococcus bacteria are a leading cause of healthcare-associated infections, such as pneumonia, bacteremia, and heart valve and bone infections. In 2011, methicillin-resistant S. aureus (MRSA) caused more than 80,000 serious infections and 11,285 related deaths in the United States. Read about experimental therapies to prevent these infections: www.nih.gov/news-events/news-releases/us-hospitals-testin... Credit: National Institute of Allergy and Infectious Diseases, NIH

[gmartinezmolina]

Klebsiella Bacteria por NIH Image Gallery Por Flickr: Klebsiella bacteria cause about 10 percent of all hospital-acquired infections in the United States. Researchers are developing a promising alternative to antibiotic treatment for infections caused by Klebsiella pneumoniae bacteria resistant to carbapenem antibiotics. The approach uses antibodies to target the K. pneumoniae protective capsule polysaccharide, allowing immune system cells called neutrophils to attack and kill the bacteria. The early stage, in vitro research was conducted by scientists at the National Institute of Allergy and Infectious Diseases’ (NIAID) Rocky Mountain Laboratories and the New Jersey Medical School-Rutgers University. More info: www.nih.gov/news-events/news-releases/nih-scientists-desc... Credit: National Institute on Allergy and Infectious Diseases, NIH