:"How does Lolita relate to people who despise her brother's orientation?"
Well.. Lolita treats such people especially negatively if they affect her brother Leim.
Lolita if they start to prize her for her bisexuality (she is bi and demisexual (you can Google if you don't know)).. She doesn't give a damn about it, and it's nothing to her compared to other insults directed at her.
But about Leim: Leim is a gentle man at heart and being bullied and insulted for his pansexuality affects him very much.
He's been exposed to this since he was a teenager, when he first tried a teenage relationship with a girl, and then a couple of years later with a guy. After that, they started bullying him at school, and on the street too, since he lived in a disadvantaged area at the time and most of them were against LGBT people.
Bullying and pressure on his weak psyche, as well as beatings and even harassment from classmates affected him for the worse: depression, PTSD, thoughts about sui.. Ahem, and attempts to get rid of the torment.
After Lolita entered the room on time and called an ambulance, he was admitted to the hospital, and then he was treated in a mental hospital, and then when he recovered, with Lolita's persuasion, he was transferred to home treatment.
Therefore, Lolita is now trying to protect him from problems and bullying, because after all, a couple of years ago she officially became her brother's guardian and now she is responsible for his health until adulthood. She appreciates her younger brother very much. Perhaps because of this, her worldview began to change and she soon accepted her orientation after several years.
"Driving in my car🚗, right after a beer🍺 Hey, that bump is shaped like a deer🦌 DUI?🍷 How about you die🪦 I'll go 100💯 miles🛣, in an hour🕐🕑 Little🤏 do you know🧐, I'm filled up on gas⛽️I'ma get, your fountain⛲️making ass🍑 Pulverize this fuck, with my Burgentrück🛻 It seems you're out of luck🍀 TRUCK!🛻"