Preparation of pyrrolidine carbonyl chloride on +100g scale.
On the gifs you can see the beginning of the addition of the pyrrolidine to a solution containing a LOT (~200 g) of triphosgene.
Triphosgene (bis(trichloromethyl) carbonate is a chemical compound that is used as a safer substitute for phosgene, because at room temperature it is a solid crystal, as opposed to phosgene which is a gas. It is a great reagent, since it could be easily handled and if it’s in a solution it decomposes to phosgene and reacts as I would use phosgene.
On the gifs as the pyrrolidine contacts with the phosgene containing atmosphere it immediately reacts with it producing HCl gas what reacts with the pyrrolidine to form pyrrolidine x HCl which is a solid compounds and could be observed as fog in the glass.
Interesting fact: phosgene is HIGHLY TOXIC, so great care should be taken while working with it, always use PPE and a WELL working fume hood, but /do not try it out/ it has an odor in high dilution similar to freshly cut grass.
