My mood in quarantine
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seen from United States

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My mood in quarantine
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SARS coronavirus (SARS-CoV), the causative agent of the large SARS outbreak in 2003, originated in bats. Many SARS-like coronaviruses (SL-CoVs) have been detected in bats, particularly those that reside in China, Europe, and Africa. To further understand ...
Abstract
SARS coronavirus (SARS-CoV), the causative agent of the large SARS outbreak in 2003, originated in bats. Many SARS-like coronaviruses (SL-CoVs) have been detected in bats, particularly those that reside in China, Europe, and Africa. To further understand the evolutionary relationship between SARS-CoV and its reservoirs, 334 bats were collected from Zhoushan city, Zhejiang province, China, between 2015 and 2017. PCR amplification of the conserved coronaviral protein RdRp detected coronaviruses in 26.65% of bats belonging to this region, and this number was influenced by seasonal changes. Full genomic analyses of the two new SL-CoVs from Zhoushan (ZXC21 and ZC45) showed that their genomes were 29,732 nucleotides (nt) and 29,802 nt in length, respectively, with 13 open reading frames (ORFs). These results revealed 81% shared nucleotide identity with human/civet SARS CoVs, which was more distant than that observed previously for bat SL-CoVs in China. Importantly, using pathogenic tests, we found that the virus can reproduce and cause disease in suckling rats, and further studies showed that the virus-like particles can be observed in the brains of suckling rats by electron microscopy. Thus, this study increased our understanding of the genetic diversity of the SL-CoVs carried by bats and also provided a new perspective to study the possibility of cross-species transmission of SL-CoVs using suckling rats as an animal model.
Emerg Microbes Infect. 2018; 7: 154. Published online 2018 Sep 12. doi: 10.1038/s41426-018-0155-5
Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee is home to the smartest and most powerful supercomputer on the planet. ‘Summit’ was recently used by two researchers to see if it could find possible drug compounds that may help fight against the SARS-CoV-2 coronavirus that is responsible for the...
So my mum’s getting tested for Covid-19 tomorrow. After some arguing with BC’s Public Health, she’s getting tested. And if she’s positive, my brothers will be getting tested as well (as the three of them live together).
And my mum’s kind of pissed. Because she’s an RN and she lived/worked through the worst of SARS in Toronto 18 years ago. And she’s frustrated to see how slow the response has been to get people tested (in BC and places like the US in particular) if they haven’t been travelling. Not to mention how pissed she is to see her coworkers not demand to test for healthcare workers who are on the front lines of this pandemic.
Maybe SARS didn’t hit Vancouver Island as bad as it hit Toronto in 2002-2003, but fuck, listen to the people with the first-hand experience of a similar virus/pandemic! They aren’t being dramatic. They were there, on the hospital floor, dealing with a similar virus all those years ago. If they don’t think you’re taking enough precautions, you probably aren’t.
Wear masks for cats, too
My mood in quarantine
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Isolated me at home
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One second is still learning, the next second will sleep forever