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IL1RAP Networks Expose Pancreatic Cancer Vulnerability
IL1RAP expressing myeloid and stromal networks form a protective tumor environment in pancreatic cancer. Targeting these cellular networks presents a therapeutic strategy for disrupting that shield and exposing the cancer to treatment. The identified vulnerability links immune and stromal components within the pancreatic tumor microenvironment.
https://insight.jci.org/articles/view/202487
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