#zohydro

[stargavze]

Stash!! Lots of oxys 10mg Lots of bars 3 zohydro 30mg

[rip-the-recipe-blog]

Trying really hard for these to be the last two.

[sobrietyplease]

Yo has anyone tried zohydro and would anyone be willing to sell me one? I wanna try it so bad.

[opiatesandspeed]

What's the difference between hydrocodone & hydrocodone/APAP

Hydrocodone with APAP is Hydrocodone with Acetaminophen(Tylenol). It is a deterrent from abusing hydrocodone so that you cannot just pop a shitload without consequences. You are only safe to take about 3,000mg of Tylenol a day so you can do the math on that with how many hydro’s you can pop before you will begin to cause liver damage. Also it deters you from blowing(snorting) the pill as well. However, there are ways around that including Cold Water Extraction(CWE). I’m not going to go in to details, but there is a youtube video that explains exactly how to do it and its a pretty simple process. Lastly, Hydrocodone by itself is just pure Hydrocodone with no ways to stop you from abusing it. You can read about the new drug that was approved earlier this year, it contains only hydrocodone. It goes by the name Zohydro. Check it out and as always stay safe and stay high. :)

[stocksagacity]

How Zogenix Can Save Itself

On Friday Zogenix’s ($ZGNX) Chief Commercial Officer resigned from the company.  A move like this is never a good sign for a drug launch only about 5 months out of the gate.  I recently published an article on Seeking Alpha criticizing the launch here: http://bit.ly/1uY8hGw The article compared the launch to other pain killers, and showed that the curve was not inspiring.  Additionally, the cost structure of ZGNX made it clear things needed to change quickly if the company was going to stay solvent or at least avoid a major restructuring.

The removal of their CCO on Friday put the stock down another 6-8% after hours, but depending on where management goes I think this could finally be a buying opportunity.  My recommendation right now is to jettison Zohydro.

With the departure of the CCO, Zogenix has the chance to pivot and sell the asset in order to focus on Relday and the DosePro platform.  With a sale of Zohydro for a royalty or small upfront, they transform the cost structure of the company and add additional cash or future profit to the balance sheet.

Reasons to get out of Zohydro:

Expensive to launch and reps only have 1 drug in their bag

Undersized sales force relative to more established pain companies

“ANewPerspective” commented in reply to my claims of a “slow launch” on June 21st with this:

I agree with Aaron Mac! 590 reps launched Opana, and that was an era without as many generic options.  So why is Zohydro going to catch up with the Opana curve with upheaval at the top and <25% the # of people selling it?

DosePro and Delray aren’t pain products, what good is it to establish a small pain franchise only to bring forward a schizophrenia asset?

Competition is coming, from companies that own the pain market.  Purdue is a controversial company, but they know the pain space as well as anyone, and other big players aren’t far behind.  If they couldn’t get traction as the only game in town, it is unlikely to get easier.

  Zogenix with a 10-15% royalty on Zohydro would be an incredibly attractive asset.

Investors would get a company with 90-100 million of cash depending on Q2 burn and no debt.

Relday is a very interesting asset after Phase I PK profile confirmation. Risperidone works, the question is if a once monthly formulation is viable.

DosePro is a validated concept, the value of which can be seen in the ENDP deal.

If no one wants Zohydro for a small royalty, then what does that really say about its uniqueness and value?

The only caveat here is that they already have an Alkermes royalty so things might get messy/tough to partner again.

Conclusion:

My first reaction to the news on Friday was a feeling of validation to my criticism of the launch.  After reflecting on things over the weekend, it looks like this might be actually a gift to investors on Monday.  Provided management makes a pivot, Zogenix can: transform its cost structure, shore up its financial situation, and remove an unfair but very real firestorm of criticism on all fronts from the stock’s story.

What do you think of this strategic suggestion?

[siksadgirl]

I looked up that Zohydro thing, apparently it's just an extended-release version of Hydrocodone. You could get the exact same effect by just taking 5 10mg Vicodin, plus you wouldn't have to mess around with them trying to break the time-release. I guess there's potential to shoot Zohydro since there's no APAP in it, but you REALLY shouldn't shoot pills, especially extended-release ones. Just thought you might like to know (I'm so fucking jealous of the US/Canadian pharm scene D:)

this was very informative thank you! I haven’t looked it up myself…it sounded too good to be true hahaa & don’t be jealous I’ll share :) but you can legally buy codeine where you’re at..and pick opium poppy pods :o I’d gladly switch living with youuu

[novena5]

ZOHYDRO - SO CLOSE

Asked my lovely dr for it and she gave me a script for it - then after two days she decided that she didn't want to prescribe it - I was really hoping to break my addiction to Vicodin - yeah, with Vicodin - I think it would help me big time to only be taking two pills a day vs handfuls - this sucks - didn't even get to try it

[scrambled-euphoria]

THE WAR ON ZOHYDRO

If you haven’t heard about Zohydro yet, now is the time to listen. Zohydro was just approved by the FDA, regardless of a 11/2 vote. The reason Zogenix claims they plan on manufacturing this drug, is for the patients suffering from severe pain. Zohydro does not contain Acetaminophen, like most other pain medications, such as Vicodin. Zogenix claims that Zohyrdo would greatly benefit those patients that cannot consume Acetaminophen. 

Then why the hype about this drug? For starters, It has been approved as a Series II narcotic which lands it a spot next to Oxycontin and Vicodin, however possibly worse. Zohydro, which can be obtained at doses as high as 50mg, can easily be crushed and absorbed all at once. The potency of pure hydrocodone Bitartrate is enough to kill an average size man with just two capsules. The capsules are currently designed to Time-release over a set 12 hours. However, people are protesting the new drug, claiming it’s too easy to tamper with and more dangerous than the current popular opiate drugs being abused. Send in your thoughts about this new drug! We would be happy to provide sources and more information for those interested.