The Ubiquitin Diary

Appetite for Destruction  |  Biology student shenanigans

[microscope-world]

Cirrhosis of the liver captured under the clinical microscope at 400x.

[laash93-deactivated20180820]

😂😂😂😭😭😭

[cranquis]

The Krebs Cycle Cycle

(Inspired by the very first CranquisMail ever.)

[dxmedstudent]

:O

[microscope-world]

Viral pneumonia of the lung captured under a biological microscope at 40x.

[biolegend]

Well if you’re going to do it all over again, be sure to check our protocol: https://www.biolegend.com/technical_protocols

[23pairofchromosomes]

Some facts about human brain:

• Your brain keeps developing until your late 40s

• New brain connections are created every time you form memory.

• Your brain uses 20% of the total oxygen in your body.

• 60% of your brain is fat.

• The human brain has the same consistency as tofu.

• The smell of chocolate increases theta brain waves, which triggers relaxation.

[altafpatel]

Cells of our immune system simplified :)

[microscope-world]

Oat cell carcinoma (small cell lung cancer) captured under a biological microscope at 40x.

[bpod-bpod]

Building Asteroids

For a blockbuster movie, you need more than an A-list cast, you need a supporting crew to help them shine. In the human brain, neurons are the stars of the show but they wouldn’t work properly without support too. Cells called astrocytes do just this but studying their effects on neurons is often limited to human brain explants, which are in short supply. Researchers now present lab-grown 3D models – organoids – made by growing astrocytes and neurons, created from human pluripotent stem cells, in a dish together. They named these organoids asteroids (pictured). Growing astrocytes (green) with a high density of neurons (red) produced astrocytes with complex structures similar to those seen in the human brain, visualised here using fluorescent microscopy. The team were able to control the exact number of cells grown together, resulting in a tightly controlled system suitable for modelling disease and drug screening.

Written by Lux Fatimathas

Image from work by Robert Krencik and colleagues

Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA

Image copyright held by the original authors

Published in Stem Cell Reports, November 2017

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[tangledwing]

Individually labeled axons in an embryonic chick ciliary ganglion. 30x (objective lens magnification).Technique: Confocal,Tissue Clearing, Brainbow (labeling technique). Dr. Ryo Egawa, Nagoya University, Graduate School of Medicine.

[johnmarksutton]

Plot twist: he can’t remember because that’s HIS brain in that jar…

[mrlemniscate]

Three medical illustrations from a 1903 medical book. Star Publishing, Chicago.

[septemberstudiesblog]

More printed notes on Muji looseleaf paper 🙂📝 . . . #studygram #studyblr #studycommuity #studyinspo #studyinspiration #studyspo #studyaccount #studyblog #studymotivation #studygrind #goodnotes #goodnotesapp #mcat #premed #medschool #studynotes #ipadpro #medicalschool #premedstudent #biology #studymode #studyhard #studygramcommunity #studyblog (at Long Island, New York)

[msnaflah-blog]

Some illustrations I did for a orthopedic book

[biomedicool]

Cell Cycle - Cancer

Quiescent/ senescent 

Gap 0/G0 

A resting phase where the cell has left the cycle and has stopped dividing. 

Interphase

 Gap 1 / G1 

Cells increase in size. The G1 checkpoint control mechanism ensures that everything is ready for DNA synthesis. 

DNA Synthesis / S 

DNA replication occurs during this phase. 

Gap 2 / G2 

During the gap between DNA synthesis and mitosis, the cell will continue to grow. The G2 checkpoint control mechanism ensures that everything is ready to enter the M (mitosis) phase and divide. 

Cell division 

Mitosis / M 

Cell growth stops at this stage and cellular energy is focused on the orderly division into two daughter cells. 

A checkpoint in the middle of mitosis (Metaphase Checkpoint) ensures that the cell is ready to complete cell division. 

Cyclins 

family of proteins control cells through the cell cycle by activating cyclin-dependent kinases (CDKs). 

G1 /S cyclins – essential for the control of the cell cycle at the G1/S transition, Cyclin D/ CDK4, Cyclin D /CDK6, and Cyclin E / CDK2 – regulates transition from G1 to S phase. 

G2 /M cyclins – essential for the control of the cell cycle at the G2/M transition (mitosis). G2 /M cyclins accumulate steadily during G2 and are abruptly destroyed as cells exit from mitosis. Cyclin B / CDK1 – regulates progression from G2 to M phase 

[cellimagelibrary]

Image of the Week – April 16, 2018

CIL:40965 - http://www.cellimagelibrary.org/images/40965

Description: Brightfield micrograph of a living diatom (Mediopyxis helysia) showing the cell nuclei and golden chloroplasts. There is a bacteria colony in mucilage located on the top of the diatom. The image won the Ninth Prize, 2011 Olympus BioScapes Digital Imaging Competition®.

Authors: Wolfgang Bettighofer and 2011 Olympus BioScapes Digital Imaging Competition®

Licensing: Attribution Non-Commercial No Derivatives: This image is licensed under a Creative Commons Attribution, Non-Commercial, No Derivatives License

[soundstudy]

One of my study references from neuro last semester. That class was hell, but it’s over now, thank god, although I will have the same professor for a class this fall. We’ll see how that turns out.