
roma★
cherry valley forever
NASA
we're not kids anymore.

titsay
hello vonnie
Claire Keane

shark vs the universe
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Alisa U Zemlji Chuda
Mike Driver
sheepfilms

❣ Chile in a Photography ❣

PR's Tumblrdome
Jules of Nature
Sweet Seals For You, Always

Kaledo Art
dirt enthusiast
h

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@audreycataplexy
Larger than a necklace, but can be worn as such. This alert is much easier to read than the smaller necklaces.
THIS GUY IS LIKE DEATH’S SON OR SOMETHING AND NOTHING YOU SAY CAN CONVINCE ME OTHERWISE
I like how this guy is concerned but not concerned enough to let go of his cart
he’s like “why does this keep happening to me”
To me, this looks like a bunch of people getting cataplectic.
Good informative article about narcolepsy and how often people have trouble getting diagnosed
I tend to be either 3,4,5 or 6 (the four across the top going from the top right corner).
What about you guys?s
Well, it doesn't matter now that I've been talking about this kind of idea for a year or so, because Google just made it. Still, I'm glad it exists.
When I think of something funny and haven't had a chance to articulate it before I fall down, people can get pretty confused. Out of nowhere, it seems, Audrey falls down. "What is it this time?" they ask. Then they have to wait until I stop laughing in my paralysis for me to tell them what was funny. Often I start laughing again, so I don't even try to get up before I explain the trigger.
http://med.stanford.edu/psychiatry/narcolepsy/movies/dogs.avi
As the NBA and NHL playoffs start, a Harvard sleep specialist advises rest, not more practice, for championship teams.
"Summary: Sleep deprivation is known to impair a range of functions, including immune regulation and metabolic control, as well as neurocognitive processes, such as learning and memory [1]. But evidence for the role of sleep in regulating our emotional brain-state is surprisingly scarce, and while the dysregulation of affective stability following sleep loss has received subjective documentation [2,3], any neural examination remains absent. Clinical evidence suggests that sleep and emotion interact; nearly all psychiatric and neurological disorders expressing sleep disruption display corresponding symptoms of affective imbalance [4]. Independent of sleep, knowledge of the basic neural and cognitive mechanisms regulating emotion is remarkably advanced. The amygdala has a well-documented role in the processing of emotionally salient information, particularly aversive stimuli [5,6]. The extent of amygdala engagement can also be influenced by a variety of connected systems, particularly the medial-prefrontal cortex (MPFC); the MPFC is proposed to exert an inhibitory, top-down control of amygdala function, resulting in contextually appropriate emotional responses [5,6]. We have focused on this network and using functional magnetic resonance image (fMRI) have obtained evidence, reported here, that a lack of sleep inappropriately modulates the human emotional brain response to negative aversive stimuli (see Supplemental data available on-line with this issue)." http://dx.doi.org/10.1016/j.cub.2007.08.007
Successful Gene Therapy in a Narcolepsy Animal Model
"Narcolepsy is caused by selective loss of the orexin/hypocretin-producing neurons of the hypothalamus."
In mice, “We used gene therapy to restore orexin signaling in a mouse model of narcolepsy.”
"These substantial improvements in sleepiness and other symptoms of narcolepsy demonstrate the effectiveness of orexin gene therapy in a mouse model of narcolepsy.." (Kantor et al.)
what a great nap, i feel totally disoriented and i’m frothing with hate
In this short talk, Arianna Huffington shares a small idea that can awaken much bigger ones: the power of a good night's sleep. Instead of bragging about our sleep deficits, she urges us to shut our eyes and see the big picture: We can sleep our way to increased productivity and happiness -- and smarter decision-making.
Narcolepsy Awareness Programs and Services