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@chagasdiseaseday
Webinario- El Chagas existe y podemos eliminarlo.
Webinario: El Chagas existe y podemos eliminarlo.
Fecha: 10 de abril de 2024
11:00 a.m. – Hora del Este de Estados Unidos 12:00 p.m. – Argentina 10:00 am. - Colombia 09:00 a.m. – México y Centroamérica
Plataforma: Zoom
Día Mundial de la Enfermedad de Chagas 2024
Diagnóstico temprano, tratamiento y seguimiento.
Lema 2024: Diagnóstico temprano, tratamiento y seguimiento. Concientizar a los pacientes, sus familias y trabajadores de salud sobre la necesidad de hacer un diagnóstico temprano (oportuno) y un acompañamiento de por vida de las personas afectadas por la enfermedad.
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Conversatorio: El Chagas existe y podemos eliminarlo.
El Día Mundial de la Enfermedad de Chagas se celebra el 14 de abril para concientizar sobre esta enfermedad desatendida.
PAHO-WHO, OPS/OMS Argentina - PAHO/WHO Argentina, OPS/OMS México - PAHO/WHO Mexico, Coalición Global de Chagas/ Chagas Global Coalition
Congenital Chagas Disease: where are the knowledge and research gaps?
In this ISNTD Connect, Dr Marina Gold (Anthropologist & CEO Mundo Sano Foundation) and Elise Rapp (Nurse, Biologist, PhD-student in Social Sciences University of Lausanne and HESAV, HES-SO, Switzerland) present a scoping review of the literature on congenital Chagas Disease and share some of the main knowledge and research trends and gaps. Following a presentation of published work, the discussion highlights the pivotal role of social sciences in tackling neglected diseases, from a better understanding of the social determinants of health to breaking down the barriers to treatments access and lifelong care.
"Congenital Chagas Disease: where are the knowledge and research gaps?" Recorded online as part of the ISNTD Connect series on Neglected Tropical Diseases.
El Chaga se transmite, principalmente, a través de la picadura de insectos triatominos infectados
Esta enfermedad también se conoce como tripanosomiasis americana y es causada por el parásito Trypanosoma cruzi
El 14 de abril de cada año se conmemora el Día Mundial de la Enfermedad de Chagas, una fecha que busca sensibilizar y concientizar a la población sobre esta enfermedad infecciosa que afecta a millones de personas en todo el mundo.
Esta enfermedad también se conoce como tripanosomiasis americana y es causada por el parásito Trypanosoma cruzi.
La Enfermedad de Chagas se transmite, principalmente, a través de la picadura de insectos triatominos infectados, también conocidos como chinches besuconas, que suelen habitar en grietas, huecos de paredes y tejados de casas.
El parásito también puede transmitirse de la madre al hijo durante el embarazo o el parto, así como por transfusiones de sangre, trasplantes de órganos o el consumo de alimentos contaminados.
Esta enfermedad afecta a más de 6 millones de personas en todo el mundo, especialmente en América Latina, donde se estima que hay unos 70 millones de personas en riesgo de contraerla.
La mayoría de los casos con esta enfermedad se registran en zonas rurales y pobres, donde las viviendas suelen estar en malas condiciones y no se cuenta con medidas adecuadas para controlar las plagas.
Esta enfermedad es endémica en América Latina, aunque se ha reportado en otras regiones del mundo debido a la migración de personas infectadas.
Actualmente, hay registro de la enfermedad en 21 países de América Latina, principalmente en las zonas calidad y húmedas del continente.
En 2019, especialistas de la UNAM y la Secretaría de Salud estimaron que había más de un millón de personas en México con la enfermedad de Chagas, principalmente en los estados de Veracruz, Oaxaca, Yucatán, Morelos, Chiapas, Jalisco y Estado de México.
Además, la Secretaría de Salud estima que durante 2022 se diagnosticaron 860 casos de enfermedad de Chagas.
Esta enfermedad también se conoce como tripanosomiasis americana y es causada por el parásito Trypanosoma cruzi
Focusing on the integration of universal care and surveillance at the primary care level.
14 April is World Chagas Disease Day and this year the focus is on increasing awareness of Chagas disease, and on providing access to crucial care and implementing disease surveillance, at the primary health care level.
According to the World Health Organization (WHO), an estimated 6-7 million people worldwide are infected with Trypanosoma cruzi, the parasite that causes Chagas disease, leading to some 12,000 deaths every year and leaving some 75 million people at risk of infection. Annual incidence is 30-40,000 cases, but in many countries, detection rates are low (less than 10% and often less than 1%) and people suffering with the disease often encounter significant barriers to diagnosis and adequate healthcare.
Chagas disease is often called a "silent disease" because most patients have no symptoms either during the acute or the chronic phases of infection, until when damages are too advanced to be reversed. It remains a public health problem, especially in several endemic areas of continental Latin America, where the burden on health systems is high. The disease is curable when treatment is provided soon after infection, and detection and monitoring of the disease can be carried out at the first level of medical care. The decentralization of diagnostic and care services and making these part of mainstream national health systems, can therefore play a crucial role in ensuring effective case detection, notification, and management.
Speaking ahead of World Chagas Day, the Director of WHO’s Global NTD Programme, Dr Ibrahima Socé Fall said, “Chagas disease remains a blight on the lives of too many people, across Latin America and throughout the world. I join with my colleagues on the ground in calling for reinforced primary health care to better detect and diagnose cases and to ensure that more and more people are able to benefit from the treatments available to combat this debilitating disease”.
14 April is World Chagas Disease Day and this year the focus is on increasing awareness of Chagas disease, and on providing access to crucia
World Chagas Disease Day 2023 to focus on integrating universal care and surveillance at the primary care level.
Events in the month of World Chagas Disease Day 2023.
It is estimated that, in Latin America alone, between 6 and 8 million people are infected with the parasite, and 99% of these are not receiving treatment, either because they are unaware of their infection or because they do not know that treatment exists. The potential spread of the disease is also a cause for considerable concern: 65 million people live in areas of exposure and are at risk of contracting Chagas disease, and 28,000 new cases occur every year.
While significant progress has been made in the Americas on controlling vector-borne transmission, disease prevalence remains high in endemic areas due to a lack of sustained control. At the same time, the movement of affected populations to urban areas and other countries has led to the spread of the disease. As a result of these migratory flows, Chagas disease is now also a public health problem in countries where vector-borne transmission has never been documented.
Diverse and complex political, social and economic factors have favoured these migratory flows, with the search for higher-paying jobs and a better quality of life playing a decisive role in the spread of the infection. Chagas disease is now found in areas receiving migrant populations where no vector-borne transmission occurs. Nonetheless, even there, the infection continues to be transmitted in other ways. The disease is an emerging health problem in the United States, Canada and Spain as well as in other countries in Europe and the Western Pacific.
CONTEXT
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, a parasite that nests in various tissues, causing irreversible cardiac damage in 30% of patients with chronic disease and neurological or digestive lesions in 10%. Social and environmental factors are important in the areas where the disease is endemic and there is evidence of vector-borne transmission. Living in poor quality housing, in close proximity to animals and in rural or suburban areas, especially those affected by poverty and marginalisation, are all factors that increase the risk of infection. The disease particularly targets the poorest and most vulnerable populations because the principal insect vector is a bloodsucking bug that lives in the adobe walls and thatched roofs typical of poor dwellings in rural areas and it feeds on people living in such houses. The deplorable consequence of the current situation is that, according to data published by the Pan American Health Organization (PAHO), Chagas disease still causes some 12,000 deaths annually worldwide. A recent study by the Brazilian Ministry of Health estimated that, in Brazil alone, 6,000 people die every year from Chagas disease.
WHAT IS THE COST?
The real economic burden of Chagas disease can be hidden for years because many of those infected remain asymptomatic for over a decade. Since diagnostic tests are rarely used, many people are unaware of their infection because it has never been diagnosed. However, once the patient starts to have clinical signs—including cardiomyopathy, heart failure or dilation of the oesophagus or colon—the costs of health care, disability support and death are high.
Moreover, since these medical problems are chronic and progressive, the cost accumulates over many years. On average, the annual cost of health care per infected person is US$474, and the cumulative lifetime cost is US$3,456. This figure represents the average cost taking into account both the patients who develop complications that require complex and expensive interventions (approximately 30% to 35% of cases) and those living with the infection who never develop symptoms (65% to 70%). It does not, therefore, reflect the great range between the two extremes. Moreover, this figure only reflects the direct cost of health care. Low productivity, permanent disability, loss of income due to work absenteeism and other associated social costs amount to an average annual cost of US$4,660 per year per infected person and an accumulated average lifetime cost of US$27,770.
HOW IS CHAGAS DISEASE TREATED?
Chagas disease can be treated with the antiparasitic drugs benznidazole and nifurtimox. Both drugs are almost 100% effective in infected newborn babies and highly effective in the treatment of patients in the acute stage of the disease. However, the efficacy of both drugs decreases the longer a person has been infected. Patients with chronic disease may also require treatment for cardiac or gastrointestinal manifestations. Aetiological treatment should be offered to infected adults, especially those who have no symptoms. In addition to the social and medical benefits of controlling Chagas disease, the economic benefits are also important. The cost of aetiological treatment is equivalent to less than 1% of the social cost associated with the disease. This means that every dollar invested in such treatment can yield a savings of up to US$830 per patient who develops the disease.
WHY IS IT IMPORTANT TO ACT NOW?
Immediate action to combat Chagas disease is important because people are still dying as a result of this parasitic infection without ever being diagnosed or receiving treatment. Moreover, the scientific challenges that need to be addressed if we are to reduce the burden of Chagas disease do not receive sufficient global funding and the problem continues to suffer from a lack of visibility. Funding for research and development (R&D) in Chagas disease represents only 0.5% of the global budget for neglected diseases. National programmes in endemic countries have typically focused more on vector control and less on the diagnosis and treatment of patients. However, it has now been shown that treatment can effectively control the disease in most settings. Technical limitations no longer seem to be an obstacle to improving the treatment of those affected. Rather than being a due to technical constraints, the current lack of adequate treatment appears to be due to insufficient capacity for action on the part of the stakeholders and institutions responsible. At the same time, it is essential to continue researching and developing new tools. The available drugs are not very effective in the chronic phase of the disease and involve lengthy treatment cycles (two months). Furthermore, treatment must be supervised by medical personnel because of the possibility of adverse effects. The development of new tools for diagnosing the disease and monitoring treatment remains crucial; we need to identify biomarkers of disease progression and cure that can be used to monitor the effectiveness of therapy in patients with chronic disease.
WHAT IS NEEDED?
What is urgently needed today is an integrated approach to the disease comprising three main lines of action:
1. Prevention of new cases
A multifaceted strategy is needed to interrupt the transmission of Chagas disease, including vector control, blood screening to prevent infection through transfusion and organ transplantation, and control of vertical transmission from mother to child. Vector control, which is the most effective method of preventing vector-borne transmission in Latin America, involves three types of interventions: spraying houses with insecticides to eliminate the vector, improving housing to prevent reinfestation, and improving food hygiene standards. Blood and organs donated by individuals at risk of exposure should be screened for the parasite to prevent the transmission of infection. Congenital transmission is managed by screening pregnant women and monitoring both mother and child after delivery.
2. Aetiological treatment
The infection can be cured, but patients cannot be treated until they have been diagnosed. An active search programme is required to identify infected people who should be treated, but this is a strategy rarely implemented in the affected countries. Once a patient has been diagnosed, aetiological treatment should be started immediately regardless of whether the disease is in the acute or chronic stage. To continue the process of diagnosis and treatment, the next step is to screen family members and the local population who may be at risk.
3. Coordination of R&D
To coordinate R&D it is essential to gather information on the areas already covered, to identify potential gaps, and to draw up an R&D agenda defining the priorities that respond to the needs of the affected countries. Coordination is also required to ensure that experiences are exchanged and that intervention programmes are implemented to evaluate the new tools that have been developed.
Events in the month of World Chagas Disease Day 2023 03 April 2023 ...
Highlight advances and remaining challenges for Chagas disease.
This event, co-organized by the Brazilian Embassy, San Diego State University, the University of California-San Diego, and DNDi, aims to highlight advances and remaining challenges for Chagas disease and the many people it impacts throughout the world.
SCHEDULE AT-A-GLANCE
8:30-9:00am (Pacific Time Zone) - IN PERSON ONLY - Check-in (light refreshments)
9:00 - 9:05am* Opening Remarks by Deputy Consul General of Brazil in Los Angeles
9:05 - 9:10am *Welcome Message from SDSU - Dr. Tom Novotny and Dr. Eyal Oren
9:10 - 9:25am *Patient Advocate Testimonial of living with Chagas Disease
9:25 - 9:45am *Mr. Daniel R. Pinto, Brazilian Consulate - The discovery of Chagas and the birth of public health in Brazil
9:45. -10:05am *Dr. Paula Stigler Granados, SDSU - Chagas disease in the U.S.
10:05 - 10:25am *Dr. Carolina Batista, Lancet Commission)- NTD no more: The geographical expansion of Chagas.
10:25 - 11:00am *Coffee Break
11:00 - 11:20am *Dr. Colin Forsyth, DNDi - The role of DNDi and the Chagas Platform
11:20 - 11:40am * Dr. Sheba Meymandi, CECD-UCLA - The experience of the Center of Excellence in Chagas Disease
11:40 - 12:00pm *Dr. Maria Bellio, UFRJ and SBI -The immune response in Chagas disease.
12:00 - 12:20pm *Dr. Roberto Saraiva, Fiocruz - Chagas Disease in Brazil: Current Challenges.
12:20 - 12:40pm *Dr. Jair Siqueira-Neto, UCSD - Therapies for Chagas disease.
12:40 - 1:00pm *Panel with speakers moderated by Mr. Daniel Pinto.
DOWNLOAD THE SCHEDULE
Schedule - World Chagas Disease Day – April 14, 2023 (pdf)
Registration.
Welcome to World Chagas Day 2023 from San Diego State University! This is an in-person and online event, please register below. If attendi
The theme for World Chagas Disease Day 2023 is Time to integrate Chagas disease into primary health care.
The theme for World Chagas Disease Day 2023 is Time to integrate Chagas disease into primary health care. In many countries, there are low d
There are approximately 6-7 million people infected with Chagas disease worldwide, with 10,000 deaths, every year. World Chagas Diseases Day 2023.
Calling for equitable access to health care and services for everyone affected by the disease.
In 2022 we are shining a spotlight on Chagas disease, the suffering it causes and are calling for equitable access to health care and services for everyone affected by the disease. The theme for the World Chagas disease Day 2022 is finding and reporting every case to defeat Chagas disease. In many countries, there are low detection rates (<10%, frequently <1%) and frequent barriers to access adequate healthcare.
Call for action to defeat Chagas disease.
Actions for Health workers and health partners
Actions for general public
Actions for Decision makers and donors
Action for Academia and researchers
Chagas disease affects between 6 and 7 million people worldwide and kills 10,000 people annually. In Latin America, it causes more deaths th
On World Chagas Disease Day 2021 (14th of April), a new initiative co-financed by Unitaid and the Brazilian Ministry of Health aims to improve access to affordable diagnostics, better treatment, and comprehensive care for women and new-borns in four endemic countries: Brazil, Bolivia, Colombia, and Paraguay.
Comprehensive, equitable health care services for all people affected by Chagas Disease
In 2021 we are shining a spotlight on Chagas disease, the suffering it causes and are calling for comprehensive and equitable access to health care and services for everyone affected by the disease.
Chagas disease is prevalent among poor populations of continental Latin America but is increasingly being detected in other countries and continents. It is often termed as a “silent and silenced disease” as the infected majority have no symptoms or extremely mild symptom.
Chagas disease patients comprise risk groups that can present severe forms of COVID-19 and should be prioritized for vaccination. There are approximately 6-7 million people infected with Chagas disease worldwide, with 10,000 deaths, every year.