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@chronicwastingdiseasee
anytime im upset i just look up skobeloff green and feel instantly better
the sheer second-hand embarrassment i get when i hear someone romanticizing a disease
yuck
they romanticise what now
saw people romanticizing prion diseases yesterday 💔😬
prion? of all the other diseases?
i doubt that person knows what prion does to one
if they knew but still romanticised it, im done with humanity
i believe they do know about it to so some extent (taking the fact that their name was literally a prion disease and that’s all they posted about in their blog)
just weird, man
what in the bloody fucking hell???
give that guy the prion disease lets see how they handle it
yes, you can be obsessed with prion diseases but only in a “this is fascinating to research” way. i don’t think they explicitly stated but everything in their blog just rubbed me the wrong way…
exactly
usually that feeling is right
“what is your favourite prion disease”
the wording i do not like. could’ve made it sound more sane by adding “to research” in it.
people are the way they are, i guess.
yeah that wording is concerning
oh well this really feels like its about my blog / at least i think i said something very similar! if so, im very sorry it came off that way, english is not my first language :( i will fix the wording and i hope people wont take it the wrong way!!!!!!
the sheer second-hand embarrassment i get when i hear someone romanticizing a disease
yuck
they romanticise what now
saw people romanticizing prion diseases yesterday 💔😬
prion? of all the other diseases?
i doubt that person knows what prion does to one
if they knew but still romanticised it, im done with humanity
i believe they do know about it to so some extent (taking the fact that their name was literally a prion disease and that’s all they posted about in their blog)
just weird, man
what in the bloody fucking hell???
give that guy the prion disease lets see how they handle it
yes, you can be obsessed with prion diseases but only in a “this is fascinating to research” way. i don’t think they explicitly stated but everything in their blog just rubbed me the wrong way…
i hope i dont come off this way </3
this is the only site ive found people who share my special interest and ive talked to so many nice people just during the last two days so ive been super happy abt that!!!!! never in my ten years of being interested by this subject ive met so many likeminded people
so when i say i love prions and prions and diseases, i dont mean to be insensitive!!! i know how many people find them like the scariest thing ever and also how people with chronic illnesses or other medical issues struggle every day.. hell im totally not a healthy person myself either (physically nor mentally) but i just dont talk about it here. this is my special interest blog only meant for me to ramble about how interested i am in it! and nothing else, i dont like talking about myself online
i will always try to tag everything properly because i know some dont like medical stuff! if i gross anyone out just block me and if something i say makes you feel uneasy please just let me know, im passionate about my interests and not great with tone especially on the internet ^__^
sorry for ranting, this just made me think abt some stuff!!!!! i hope op can also clear everything out with the original person in the post!
this image scratches my brain
THIS IS SO CUTE !!!! i love the idea so much.. also hear me out: my sweet piano = scrapie?!
YOU YOU'RE ON MY WAVELENGTH BUDDY. CAN I DRAW THAT??
HELL YES!!
🧠 this is like the heart🩷emoji to me. it feels so kind
its 2am so im going to sleep now.. tomorrow i wanna talk about the Fore people funeral practises in more detail! good night little people in my phone 🧠 ^__^
hi scrolled through the blog. til you can’t get kuru from eating just anyone and it was only common in that one group because it was full of people who already had it. neat
yep!!! ^__^
AND! it wasn't necessarily inherent to their population. the funeral rituals their culture used went back several generations, but when discovered kuru was a relatively recent issue, particularly in women and children. this is because their cannibalism rituals involved men, particularly warriors being prioritized for muscle meats and the brains, etc being relegated to women and children - the hypothesis is that one older adult in the group developed sporadic cjd, as they would have been most at risk for it, and that was how it spread throughout the group.
YES!!!
Even though the Fore people live in such a large area that certain parts of the culture and religion differ slightly from each other, the main idea is the same. Fore people believed that there were five spirits in a person: auma, ama, kwela, aona and yesegi.
Also in fact it was also often thought that only women could handle the strongest spirits which were in the brain! And since it was their job to take care of the children they would often give some parts of the meat they were eating to them.
Auma is the first to leave the body after passing away and it will wish goodbye to the still living loved ones before starting its journey to the afterlife. Ama and kwela are in the flesh and bones and the later will be enraged if the body is disposed of improperly. This is also a big reason why in Fore culture it was very disrespectful to bury the dead and let worms and other insects eat your loved ones.
Personally i think that is very thoughtful, i hate how usually the practise of endocannibalism is so over the top demonised! Especially how people in europe were consuming other people for ages just cause they thought lesser of them.. so munching on mummy powder and blood candy for treatment to any random illness was okay but if anyone outside their country cannibalised their own people for spiritual reason that was "barbaric" and "uncivilized" ??
Fore's did it out of love and respect and i think thats wonderful.
LOVE the placement of this on a math test. i lost one point on the page because i forgot a negative sign but this makes it look like he took off a point for prion disease...
HAH! c:
i had a prion researcher ik (you know the guy from the atlantic article about zoonotic cwd? that one) reccomend me fatal flaws by jay ingram i think you would loveee it
woah i havent heard of this one! just looked it up and it seems very interesting.. thanks a lot for the recommendation!! also yess that article is super awesome :3
hii theres a book called the family that couldnt sleep and its about prion diseases and its very cool! i have it in epub if you want it, anyways have a good day !
OOO YEAH i know that book but i would love to have it in epub!!!!! i hope you have an awesome day too ^__^
great comment from a video "Is Ai Slop Worse Than Cannibalism"
hi scrolled through the blog. til you can’t get kuru from eating just anyone and it was only common in that one group because it was full of people who already had it. neat
yep!!! ^__^
THIS IS SO CUTE !!!! i love the idea so much.. also hear me out: my sweet piano = scrapie?!
A current topic of interest of mine would happen to be transmissible spongiform encephalopathies, if not for how honestly horrifying the concept of them is. Now, I don't expect everyone passing by to know what this is, so allow me to explain. Transmissible spongiform encephalopathies occur when the proteins of the brain begin to fold incorrectly, which will slowly lead to sponge-like holes in the brain — hence "spongiform". Additionally, this form of it can be transferred, though the means of doing so can be considered a bit odd. In most cases, one might contract such a condition by eating something that held onto one of those proteins, better known as prions. Prions are very resilient little things, they will survive being put through a medical-grade autoclave, therefore meaning that any meat prepared from an infected organism will be unsafe. Additionally, the plants that an infected organism died on will also be unsafe for consumption for years after that death.
While several versions of transmissible spongiform encephalopathies exist, there are two that I would consider the most notable. Bovine spongiform encephalopaty, better known as Mad Cow Disease, and Chronic Wasting Disease. Mad Cow is certainly the best known out of those two, but Chronic Wasting Disease is still a present issue that can be observed in deer.
There was a notable outbreak of bovine spongiform encephalopathy within the United Kingdom during the 1980s, caused by the poor quality feed cows were given due to the low regulation and cheap price that feed gave. Cows within the UK were fed a type of meat and bone meal back then, rather than any sort of plant-based feed they should have been getting. However, some of the sheep used to make this feed ended up having Scrapie, the version of transmissible spongiform encephalopathy that can affect sheep. Many cows ended up exhibiting odd behaviors due to infection, such as behavioral changes and worsened coordination. Some cows would exhibit aggression due to the disease, which I assume was where the nickname of "Mad Cow" came from, though that's just my speculation. Panic grew, however, because many feared this disease would be transmitted to humans by eating infected meat. Unfortunately, this ended up being the case, though the total number of those affected will continue to climb due to the fact that prion diseases can incubate for very long times. Because of this, anyone who resided in the UK during the 1980s is not allowed to donate blood, due to fear the disease will transmit to the recipient.
As for Chronic Wasting disease, the signs are similar. Many infected deer display odd behaviors, as well as poor coordination. Others fail to eat, resulting in them wasting away and starving to death. This disease, unlike Mad Cow, is not yet contained, so eating any sort of deer meat can always pose the risk of being infected. This can also be spread from deer to deer, specifically because the malformed prions can survive on vegetation for a very long time. If you see any sort of cervine acting odd, you're supposed to report it to interior officials.
There's certainly more to be said about ths topic, like the several types of these diseases that appear in humans, but I have a feeling most have stopped reading seriously at this point. While I'd certainly love to say more, and you're completely welcome to ask, I also recommend anyone interested to conduct their own research. This is simply one of many topics I hold some knowledge on, and I anticipate making more long posts explaining things in the future. It is an outlet to release my knowledge without overwhelming my fellow classmates and Kusuo-kun's friend group.
akemod: I thought of posting something like this as a joke and then I was two paragraphs in. sorry.
What are prion diseases?
Also known as transmissible spongiform encephalopathies (TSEs) are rare (only causing 1-2 per cases per million people annually) misfolded form of a protein called PrP (Prion Protein) which is encoded by chromosome 20, a misfold happens when PrP undergoes a conformational conversion from its normal α-helix to a β-sheet rich structure, the β-sheet allows the prion protein to form aggregates (the clumping of biomolecules) and amyloid fibrils (an ordered composition of misfolded proteins that have assembled into insoluble fibres) which are toxic to neurons therefore disrupting neurotransmission and synaptic plasticity as well as causing spongiform degeneration (holes in brain tissue), Glial cells are activated but are ineffective at clearing prions thus leading to inflammation.
There are three different types of causes, these being
Sporadic (a spontaneous misfolding of Prpc into PrPsc) seen in Creutzfeldt-Jakob's disease, this is the most common cause
Genetic which is caused by destabilising mutations such as D178N in PrPc as seen in fatal familial insomnia
Acquired which is seen in Kuru, can be caught from contaminated surgical instruments, contaminated blood transfusions or the consumption of the human brain.