all-timer daniel molloy questions:
1. did you eat the baby?
2. are you schizophrenic, louis?
3. and then what?
4. fuck, man, are you the zodiac killer?
5. YOU BOTH FUCKED LESTAT?
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@kanayagf
all-timer daniel molloy questions:
1. did you eat the baby?
2. are you schizophrenic, louis?
3. and then what?
4. fuck, man, are you the zodiac killer?
5. YOU BOTH FUCKED LESTAT?
Nine Inch Nails promotional t shirt
simon and garfunkel beef squashed, the blowjob brothers from oasis reunited i think, taylor invited karlie to her wedding. paul mccartney it’s time to learn necromancy.
[citation not needed. no prablem]
Jenny Holzer, Black Book Posters, 1979
it’s a shame more vampire media doesn’t pull from vampire bat behavior because they’re such sweeties. they can only survive their incredibly specialized diet because bats will share blood with colony members that didn’t find a meal! there’s evidence that suggests the donors sometimes initiate this behavior themselves by approaching hungry bats! the colonies are mostly harems of females with a few males but they’ve been observed letting unrelated males in when it gets cold so they can all stay warm! cute little social critters!
@yupekosi your tags have created such a beautiful world
The real Love Story in The Goldfinch isn't Theo and Pippa or even Theo and Boris, it's Welty and Hobie.
Imagine being so loved that your lifelong partner uses the final minutes before death to fuse his soul with a random 13 year old kid's - just to send back a piece of his childhood to you from beyond the grave, just to let you know that he was thinking of you and that he loves you. To help you, now that he's leaving you to live life alone.
Imagine being so loved that your lifelong partner takes that random kid when he turns up on your doorstep days after your death, and then again years after that, & feeds him & cares for him & teaches him your trade & shrugs his shoulders at international art theft just because the way that the kid loves a painting reminds him of the way that you loved that same painting.
i also think. i also think every day jesper campaigns for kaz to change his title from bastard of the barrel to baddest bitch of the barrel. he’s like kaz listen you’d poll so highly with the queer community of ketterdam and kaz is like with every word you say you make me more homophobic and jesper is like well you weren’t very homophobic last night and then kaz hate crimes him.
Long COVID patients can experience severe energy crashes after physical exertion. New research provides clear evidence that there's a biolog
Full Transcript at the link; 3-minute listen.
Quote:
By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.
Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.
"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.
The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.
"This is a very real disease," says Charlton. "We see this at basically every parameter that we measure."
I feel insane seeing stuff like this because this research already exists for Myalgic Encephalomyelitis, a post viral condition caused by multiple types of viral infections that a LOT of people with "Long Covid" meet the diagnostic criteria for.
This article mentions that ME/CFS is a "similar complex condition" but that's DEEPLY underreporting the similarities. The phrase "post exertional malaise" (now researchers are trying to replace it but this article uses that phrase) was INVENTED for ME/CFS. It's the only known condition, before "long covid", that causes these kinds of symptoms after exertion!
It's good to know for sure that it's the same mechanisms at play when the inciting viral infection is Covid and not, for instance, Epstein-Barr or RSV, but half the time it doesn't seem like researchers are making comparisons at all, just reinventing the wheel and acting like "long covid" is a totally new phenomenon with no previous point of comparison. There are literally drugs in human trials to try to treat the mitochondrial dysfunction in ME, this dysfunction is well-established and fairly well understood and I feel insane when ppl report on long covid without mentioning that there is already a named and studied condition that accounts for this subset of symptoms!!
SOME researchers are drawing comparisons but they're largely ME researchers who everyone else is largely cignoring because of the widespread perception that ME is a fake disease for lazy women.
That same perception btw is why "graded exercise therapy" (GET), or exercise gradually increasing in intensity, cwas for years the go-to treatment despite MOUNTAINS of evidence that it makes ME patients sicker. Some end up permanently bedbound and unable to even eat or drink without a feeding tube/IV because the damage is so bad! The GET recommendation was finally changed only in the past few years in the US and the UK, and many doctors hate that they're not allowed to recommend it anymore, because they insist despite the evidence that ME/CFS is psychological and ME patients are just "deconditioned" and too lazy to do anything about it.
Now the same kind of "treatment" is being recommended for long covid patients despite evidence showing exercise is having the same kinds of cellular effects as it does in ME patients. "Taking PEM into account" sounds gentler but I'm deeply concerned about the reinvention of GET for patients who meet all the criteria for an illness that's been shown definitively to become permanently worse with GET. This mitochondrial damage is progressive in ME, and there's no reason to believe patients who meet all the criteria of ME after Covid won't experience the same progression if they force themselves past their energy envelope in such a systematic way.
The additional finding that T cells — part of the immune system's arsenal — had infiltrated the muscles of long COVID patients also caught Iwasaki's attention, possibly indicating "an autoimmune response within the muscle cells."
This autoimmune response is well-researched for ME. Every time you overexert, you're injuring your cells more and more. It's deeply worrying that rebranded GET is being recommended for long covid patients who meet the criteria for ME when research like this study keeps showing it's the same phenomenon.
it’s rotten work. to me if it’s me.
a boyfriend is a type of parasite that lives in a beautiful woman’s house and drains her life force
love is something you do with your teeth
Sanity by Caroline Bird
I think the "pre" and "post" parts in "preposterous" should cancel each other out but everyone else seems to find my idea completely erous
recently i was looking at the most downvoted posts on r/stoicism