@mizfishuh - Tumblr Blog

middleagedresidentofriverdale

I just cringed. Lmfao WHO cares about your life??

Why do you make everything about yourself as if anyone cares??? 😭😭

Apparently a lot of people do. I have a ton of friends.

And you do too, or you wouldn't have written. Nice to meet you, new bestie!

Have a blessed day!

mizfishuh

Wow, what an ass. If you don't want to read about her life, anon, perhaps you should stay off of her blog.

middleagedresidentofriverdale

I have now watched the first 3 episodes of Not Suitable for Work and I can say I really like it. It grew progressively better with each episode. It's not trying to be anything other than what it is -- a funny, feel-good sitcom. Ideal for watching while I relax before getting ready for bed. None of the suggested couples appeal to me. 🤷‍♀️ Imo, couples are for soapy shows, not light, funny ones. I do like each of the characters, though. Abby is my fave, followed by Josh.

#nsfw #not suitable for work

lili2424

mizfishuh

Too funny. Lili's version is better, obviously, but this is good, too. 😂

itsmythang

Plus, they cheer, support and help in the cover-up of sexual crimes. Even when they are children.

jackizmydog

It’s so depressing to be frank. If you can’t see this happening in real time, you are denying reality.

mrsreinhart

Those serial killer jeans will come in handy 😭😭😭

I think she’s playing the one after the killer this time 😭

mizfishuh

Omg that is hilarious. I was trying to think of jeans that Apple wore, and then it hit me -- this is a Betty reference 🥴😅🤣

vexheart

"The number of hours we have together is actually not so large. Please linger near the door uncomfortably instead of just leaving. Please forget your scarf in my life and come back later for it."

poem by Mikko Harvey

geopsych

From each end of the hill trail

rockshitty

Nothing reminds me what a goddamn miracle modern medicine is more so than hearing stories about people who contracted the black plague in the 21st century and were prescribed antibiotics for it.

Like yeah man you got the disease that wiped out half of Europe, like, a couple separate times within written history, and we have no clue how many times before that. To cure it you have to take 14 pills and drink lots of juice. You’re gonna feel kind of crummy for a while. It’s vitally important you take all 14 pills.

sapphoandvanzetti

the thing that blows my mind is blood transfusions. for literally all of human history up until about 100 years ago if you lost enough blood that was it, you were dead, and then people just figured out how to take blood from other people and successfully give it to you and now you can come in to the hospital with a blood pressure of ohfuck/nope, the same color as the linens and they just pop a tube in your arm and casually give you some stuff that another person donated on their lunch break, and you live long enough for the doctors to find and treat your gastric bleed. Insanely cool.

findingfeather

Honestly even more, just . . . IV fluids.

The fact that we can put fluids into people via IV saves more lives than I can actually communicate. There are so, so many more ways to die when we can't do that. You can go from literally at death's door from an illness you have no other cure for, to Basically Fine, You'll Feel Icky A Bit Longer But You're Otherwise Fine and Your Own Immune System Will Work Now, from sterile saline into a vein.

Or even fucking subcutaneous, under your skin. It still gets into your system faster and bypasses any fuckery going on in your gi-tract.

But you want the other end?

I recently got the answer to a crapload of symptoms of mine and it turned out to be Crohn's. Ileal crohn's.

For most of human history there was literally nothing to do about this but hope and pray that your immune system didn't decide to rip ulcers and lesions in your digestive tract to the point where you bled out, or the point where parts of it died and killed you with sepsis, or enough to build up stricture bands of scar tissue sufficiently to cause impactions or any other really gnarly and unpleasant ways you can die because for some reason your body decides the walls of your digestive tract are the enemy and need to be dismantled cell by cell. (Including a fuckload of cancers caused by the constant damage to the cell wall.)

Even as recently as when most of the younger people reading this were small children, mostly all you could do about it was take corticosteroids when you were in a flare. And that was better than Nothing. But at the same time, corticosteroids have a potential laundry list of side effects and you want to take them as little as possible and for as brief a period as possible. And there wasn't a lot else.

I am on a medication with the proprietary name "Skyrizi" and the generic name risankizumab. It's made from taking antibodies from a non-human source and then modifying their protein sequences to be more similar to human antibodies, after which they modify them further in order to make it so that the literal only thing they do is go into my body and bind to something called "tumour necrosis factor" so that this will stop flagging my own goddamn digestive system walls for destruction by the rest of the immune system.

Please feel free to read that paragraph over again.

Modern medicine isn't perfect; there are many things we're just as helpless against as we were in the Days of Eld, and there are many ways its practitioners fail us. But also we can make a thing that goes into my body and says "hey stop self destructing you MORON!" and I have a much better chance than at any other time of not dying young of bowel cancer or bowl impaction! This is fucking insane.

transcyberism

Vitamins and micronutrients.

There used to be a common, horrific illness that sailors would get, which was mysteriously cured by limes. People know about this one, it's scurvy. But there are other horrible ways to be sick from vitamin deficiency that weren't considered curable at all, and people had no idea what caused them.

Rickets is a disease caused by vitamin D deficiency where your bones get bendy and grow in the wrong shape (it is most apparent in children). It causes permanent deformity and very easy fractures, along with debilitating pain and persistent dental issues. Historically, it was known that milk, and later, cod liver oil, would improve or prevent it, but the reason was not understood until the vitamin was discovered.

Wernicke-Korsakoff syndrome is a complication of alcoholism that leads to psychosis, dementia, and death if left untreated. Severe alcoholics used to just go completely mad before dying, basically. It ultimately results in permanent memory loss (retrograde amnesia), as well as the inability to form new memories (anterograde amnesia). It is caused by the fact that alcohol prevents the absorption of vitamin B1 (thiamine). It is treatable and preventable by giving the patient thiamine shots - if caught early, before permanent brain damage has occurred, it is fully reversible, although the underlying substance abuse issue still needs to be addressed to prevent recurrence.

Pernicious anemia is caused by vitamin B12 deficiency (in turn ultimately caused by an autoimmune issue causing poor absorption). It causes blood cells to be the wrong size and too few in number, resulting in dizziness and fatigue. It also causes neurological symptoms like tingling in the extremities, poor coordination, confusion, and, in late stages, dementia. There was no cure for pernicious anemia in the past. People would simply become anemic and die from it. That's why it's called "pernicious" - that's an old-fashioned way to say "insidious and deadly," named for its slow onset and then-incurable course. Now it is curable with vitamin tablets or periodic injections.

Cretinism, or, less stigmatizingly, congenital hypothyroidism due to iodine deficiency, is a developmental disorder caused by the inability of the thyroid gland to function properly without sufficient iodine. it causes short stature, intellectual disability, infertility, hair loss, and a large lump in the neck known as a goiter (i.e. a hypertrophic thyroid gland). It was historically associated with poor inland populations living far from the ocean (due to the protective effect of consuming seafood, which is naturally high in iodine). We now simply put iodine in table salt, and this disorder is virtually unheard of in regions where this is the case.

Neural tube defects are a leading cause of birth defects, infant mortality, and stillbirth. The most common nonlethal forms of neural tube defects include spina bifida, hydranencephaly, and encephalocele. These defects are caused by a failure of the embryonic structure that becomes the spinal canal to close properly during development, leading the central nervous system to have a distorted shape that may impair cerebrospinal fluid drainage and put pressure on the brain. In severe cases, e.g. anencephaly, the brain/spine essentially develop outside of the body, which is not compatible with life (anencephalic and iniencephalic babies typically die within hours or days; fetuses with more severe forms are usually stillborn if they are not terminated). The risk of these defects is drastically reduced by taking supplemental folic acid (vitamin B9).

Vitamin K is perhaps the most amazing one on this list. Newborns often have very low vitamin K levels due to the fact that it does not cross the placental barrier easily and is not found in high levels in breast milk. It is only produced by gut bacteria, which babies do not have when they are born, and it takes time for them to acquire the right flora from their environment. Deficiency impairs blood clotting, and in infants, can lead to brain bleeds and sudden, unexplained death. Tiny babies would simply die of brain hemorrhaging for no good reason at all. But if they're given a quick shot of vitamin K at birth, that doesn't happen.

We have cured or prevented so many diseases just with vitamins/minerals.

sparklyeevee

To be clear, people still get Wernicke-Korsakoff syndrome, partly because most people don't know what causes it and partly because you can't safely disclose a substance use disorder to most healthcare professionals under most circumstances. However, oral thiamine is better than nothing here, and you can buy that at like, the grocery store.

whetstonefires

you can also get thiamine deficiency (aka beriberi, which encompasses wernicke and korsakoff) for dietary reasons.

usually this means you're getting most of your calories from either white rice or cassava, neither of which has thiamine.

in the case of rice this wasn't historically a big problem very often, because to get the sort of soft white rice that can lead to it you have to go to the trouble of polishing away the husk that has all the vitamins, which means most of the people relying on it as their dietary staple before industrial-scale processed foods were fairly well off, and ate a varied diet. if it was, you could eat buckwheat about it.

mrsreinhart

Hal and Harper is on Roku Channel for free with ads

Ahh good to know!

lili2424

Are Mishel and Lili’s stylist a couple or just friends?

I have no idea?

mizfishuh

Maybe neither? She is an actress who was attending an event and he was listed as her stylist. 🤷‍♀️

lili2424

Classic scene stealer.

A great article about Jack.

mizfishuh

Aww! I love this for Jack!

lili2424

I’m confused about the Cooper article today. Can Lili still be nominated for an Emmy?

Yeah she is eligible as the Emmy's season runs from September - August so as HH was on Mubi in October it's in this year's pool of shows.

I hope they can get some backing for her campaign, hopefully get more people to see it 🤞.

Its so funny that they have been crashing events 😂. Cooper's love for Lili is so sweet, I hope they continue to work together for their whole careers.

mizfishuh

Cooper is sweet, I agree, but he states what his goal is in the article -- he needs to make a living in this industry and right now, the people with the money are only looking at who's winning awards.