Today I want to talk about diseases your horse can obtain in the game.
What kind of diseases exist on MDR?
On MDR there are several acute and chronic diseases.
Acute diseases can be treated by a vet, and are typically not fatal so long as they are regularly medicated.
Chronic diseases can be either genetic or obtained diseases, and both are unable to be treated.
Genetic diseases are passed on from parents to their offspring. Some are inherited as a dominant trait others as a recessive trait, which decides how the disease will play out in a horse’s life. If the disease is dominant, just one allele of the disease is enough to make a horse ill. An inherited recessive requires two alleles to make the horse sick, meaning both parents must carry the allele. Horses with only one recessive allele may be entirely healthy but may pass the disease on to their offspring. Most genetic diseases are inherited recessive.
Some genetic diseases allow a horse to live but present certain disadvantages in competitions or the daily life. Others may lead to a stillborn foal.
The second version of a chronic disease is an obtained disease. These may develop due to bad care and training on a player’s part for their horse. These horses may need special treatment and medication, and may cause a handicap in competition.
What means “Carrier” and what do I need to consider?
Carriers are horses that may carry the gene for a disease but do not actually show symptoms of the disease itself. Horses such as this carry the gene recessively, meaning they only carry one allele of the disease, preventing them from being sick. Carriers have no disadvantage in competition or breeding shows over horses which are free of genetic disease, and do not need other treatment.
However, take care not to breed two carriers who have the same genetic disease, for the produced offspring may carry the disease homozygos and become very ill or even die.
What is CA?
CA stands for “cerebellar abiotrophy”.
It is a neurologic disease, where more or less neurological errors can appear (i.e. disturbance of equilibrium). Affected horses can live with the disease but shouldn’t be entered in competitions or strenuous activity.
This genetic disease is inherited recessive.
What is HERDA?
HERDA stands for “Hereditary equine regional dermal asthenia”.
The skin of affected horses is extremely sensitive and prone to building up scar tissue, leaving the horses covered in it. Horses with this disease are viable but must be treated with utmost care.
This genetic disease is inherited recessive.
What is PSSM?
PSSM stands for “Polysaccharid storage myopathy”.
This disease causes horses to retain too much glucose within their body. Symptoms include lameness, muscle stiffness and aversion to movement. These symptoms often appear after 10-20 minutes of light work. Affected horses are viable.
This genetic disease is inherited dominant.
What is EMH?
EMH stand for “Equine malignant hyperthermia”.
Diseased horses suffer from muscle cramps and cardiac arrhythmia. However, the horses are viable.
This genetic disease is inherited dominant.
What is ASD?
ASD stand for “Segment Dysgenesis“.
It is a eye disease where cysts can build up on the eye. The horses are viable but their vision is strongly affected.
This genetic disease is inherited recessive.
What is HYPP?
HYPP stands for “Hyperkalemic periodic paralysis”.
The symptoms of HYPP are muscle cramps and fatigue. The disease becomes visible in the form of sporadic attacks. Between the attacks, the horses seem to be completely normal. The affected horses are viable.
This genetic disease is inherited dominant.
What is LFS?
LFS stands for “Lavender foal syndrome”.
The foals have neurologic perturbances and cramps and cannot stand on their own. They die shortly after birth.
This genetic disease is inherited recessive.
What is SCID?
SCID stands for “Severe combined immuno-deficiency“.
The newborn foals are missing two kinds of lymphocytes. Therefore, they have practically no immune defense and die within a few days from diseases such as diarrhea or pneumonia.
This genetic disease is inherited recessive.
What is GBED?
GBED stands for “Glycogen branching enzyme deficiency “.
These foals are missing a vital enzyme and typically die from a heart disease a few days after birth. In most cases they are typically stillborn.
This genetic disease is inherited recessive.
What is JEB?
JEB stands for “Junctional epidermolysis bullosa“.
Foals suffering from JEB lose skin from their body, and their hooves typically dissolve from the corium. Foals born with JEB die shortly after birth.
This genetic disease is inherited recessive.