Hi, you can check out my tag with books with trans female protagonists here & transfem nonbinary protagonists here for all the books I've collected & posted about with trans female & transfem protagonists. There's also a substack list of new book releases by trans feminine authors here and a lot of them do include transfem protagonists.
My personal recommendations of transfem novels from my favorite speculative fiction genres are these: (the links lead to the goodreads pages of the books)
Sundered Moon by Fae Rynn (sci-fi with mechas, lesbian erotic romance, tw: facism and mentions of arranged marriage) - multiple POVs: mostly trans women, but also one cis woman)
We won't be here tomorrow by Margaret Killjoy (sci-fi & fantasy short stories with many, many trans women MCs, tw: facism, murder)
Light from Uncommon Stars by Ryka Aoki (coming of age and sci-fi, tw: parental abuse, transphobia, csa, sexual assault)
Fierce Femmes and Notorious Liars by Kai Cheng Thom (coming of age, challenge of the traditional transgender memoir, tw: self harm, sexual assault, murder, abuse, racism, homelessness)
Principles of Non-Euclidean Romance by Ela Bambust (sci-fi, an eldritch entity takes over the body of a dead man and experiences dysphoria, very, very good, tw: dysphoria, past domestic abuse, death)
The Seep by Chana Porter (sci-fi, exploration of grief in a futuristic utopia, tw: ableism, csa)
An Unkindness of Ghosts by Rivers Solomon (sci-fi, dystopia, fighting back against slavery in space with the power of autism, tw ptsd, psychosis, sexual assault, abuse, racism, slavery) - dual POV: one nonbinary intersex person, one trans woman
The Left Hand of Dog by Si Clarke (sci-fi, space exploration, great for fans of Star Trek, tw kidnapping, anaphylactic shock) - transfem nonbinary MC
Pet by Akwaeke Emezi (utopian fantasy exploring how darkness can fester if you get complacent, tw csa (off-page, mentioned), ableism)
Psycho Nymph Exile by Porpentine Charity Heartscape (sci-fi, horror, really dark magical girl story, tw: abuse, sexual assault, sexism, transphobia, transmisogyny, trauma and ptsd)
Tell Me I'm Worthless by Alison Rumfitt (horror, haunted facist house, a modern gothic horror exposing the rotting underbelly of british society, tw: sexual assault (very explicit), facism, swastikas, body horror, racism, transphobia, terrorist attack, a lot of extreme and gruesome violence, the british)
Brainwyrms by Alison Rumfitt (horror with a body horror focus, veeeerry fucked up and dark and good!, requires a strong stomach, tw: body horror, incest, csa, sexual assault (explicit), child abuse, domestic abuse, self harm, suicide, insects, parasites, gore, terrorist attack, toxic relationship, worms)
Manhunt by Gretchen Felker-Martin (post-apocalyptic horror, twist on a gender apocalypse, fighting men & terfs, sooo much gore, tw: gore, body horror, cannibalism, survival horror, sexual assault, pregnancy, transphobia, facism)
Bang Bang Bodhisattva by Aubrey Wood (a cyberpunk sci-fi detective noir story, currently still reading it, but I'm having a great time, so adding it to the list, tw: murder, facism)
As Happy as Pirates or Burglars by Jemma Topaz (sci-fi, trans lesbian erotica with d/s)
Our Monsters by Jemma Topaz (fantasy murder mystery with a focus on erotic encounters)
In the Garden of Echo by H.S. Wolfe (horror fantasy erotica, t4tVSeverybodyelse, tw: murder, gore)
Love/Aggression by June Martin (tVSt, magic transfem realism)
These Fragile Graces, This Fugitive Heart by Izzy Wasserstein (sci-fi noir technothriller, just started it myself so I can't provide tws, but its fuuuun!!!!)
I hope you find something interesting and fun to read!