insane about life threatening diseases

hi i’m kris and this is where i put my weird incurable disease shit | tw gore for some things here | i disappear often

[t-spongiformencephalopathy]

intro post and tagging system :]

tags

cwd - posts abt chronic wasting disease

cjd - creutzfelt-jakob disease

gss - gerstmann-sträussker-scheinker disease

kuru - …kuru

fi - fatal insomnia

bse - bovine spongiform encephalopathy

eue - exotic ungulate encephalopathy

scrapie - scrapie

genP - general prion posts

txtP - my text posts

krisP - my posts in general

sillyP - silly posts about prions

fanP - fantasy/“what ifs” related to prions

imgP - prion posts w/ images

vidP - prion posts w/ videos

askP - ask answered

atcP - articles abt prions

tw/cws

there will be lots of slightly alarming things on this blog.. do not proceed if you dont want to overthink about these!! additionally, medical terminology and images will be used here so if those things make you anxious please have a wonderful day and do not proceed

self

i’m kris (he/him) and my adhd has trapped me in this blog forever and ever or until i move onto a new hyperfixation. youre welcome

feel free to send asks or whatever. i could talk for hours about these stupid genetic glitches

[t-spongiformencephalopathy]

https://deerassociation.com/the-guts-of-predatory-cats-can-destroy-cwd-prions/

The Guts of Predatory Cats Can Destroy CWD Prions

The prions that cause chronic wasting disease in deer are nearly indestructible. So it's good news to learn cat guts are their mortal enemy.

[diseases-for-center-control]

Heaven forbid a protein gets a little creative these days!! #justprionthings

[diseases-for-center-control]

Sooooooo. I may have got too funky with it, and now deer all over the country are dying :/ literally how was I supposed to know this would happen :/

Anyone want some venison?

[dqnquality]

[spell-unlocked]

NEW SPELL UNLOCKED: PRION DISEASE

[fukounagrl-deactivated20250217]

can i come over and be an off-putting, diseased deer in your living room? :3

[poll-position]

Will you be welcoming inbox trick-or-treaters this year?

YES! - Feel free to trick-or-treat in my inbox!

NO! - I would rather not participate!

Voting ended onOct 15, 2024

Please reblog if YES so your followers will know!

[verysharpfish]

*misfolds your prions* have a wonderful day!

I will have a wonderful day! I sure hope I don't start being symptomatic for a degenerative brain disease abnormally young in 10-20 years that leads to my cognitive decline and death and when my body is autopsied they discover misfolded prion proteins in my brain thereby diagnosing me with sporadic creutzfeldt jakob disease!

[t-spongiformencephalopathy]

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unfortunately in this day and age there are very little blogs focused entirely on prions. if you are a fellow prion enthusiast please show yourself

[t-spongiformencephalopathy]

An overview of animal prion diseases

Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion

“EUE is a TSE of exotic zoo ruminants of the family Bovidae. During a period overlapping with BSE epidemic, 6 greater kudu, 6 elands, 2 each of Arabian oryx and ankole cattle, and 1 each of gemsbok, nyala, scimitar-horned oryx and bison were diagnosed with EUE from UK. The affected animals had been fed meat and bone meal (MBM) derived from ruminants.”

from PMC - An Overview of Animal Prion Diseases -> Exotic Ungulate Encephalopathy

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Developing treatments for prion diseases

Researchers developed a novel method to turn off prion protein production in mice. The technique could lead to treatments for prion diseases

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officially back from hibernation, i’ll probably start posting again

[t-spongiformencephalopathy]

From the National Library of Medicine, Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice -> Results by Jonathan D. F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Melanie Desbruslais, Katie Fox, Sharon Cooper, Sabrina Cronier, Emmanuel A. Asante, Simon Mead, Sebastien Brandner, Andrew F. Hill, and John Collinge

Kuru provides our principal experience of an epidemic human prion disease and primarily affected the Fore linguistic group of the Eastern Hi

[t-spongiformencephalopathy]

From the National Library of Medicine, Protein Folding in the Cytoplasm and the Heat Shock Response -> The Cytosolic Chaperone Machinery by R. Martin Vabulas, Swasti Raychaudhuri, Manajit Hayer-Hartl, and F. Ulrich Hartl

Proteins generally must fold into precise three-dimensional conformations to fulfill their biological functions. In the cell, this fundament

[t-spongiformencephalopathy]

From the National Library of Medicine, Protein Folding in the Cytoplasm and the Heat Shock Response -> Ribosome-Associated Chaperones by R. Martin Vabulas, Swasti Raychaudhuri, Manajit Hayer-Hartl, and F. Ulrich Hartl

[t-spongiformencephalopathy]

Protein Folding in the Cytoplasm and the Heat Shock Response

Proteins generally must fold into precise three-dimensional conformations to fulfill their biological functions. In the cell, this fundament

“Chaperones such as Hsp70 prevent protein misfolding and aggregation. they are up-regulated when cells are stressed but decline during aging, which may lead to increased cellular levels of toxic aggregates.”

[t-spongiformencephalopathy]

From the National Library of Medicine, Protein Folding in the Cytoplasm and the Heat Shock Response -> Folding and Aggregation by R. Martin Vabulas, Swasti Raychaudhuri, Manajit Hayer-Hartl, and F. Ulrich Hartl

Proteins generally must fold into precise three-dimensional conformations to fulfill their biological functions. In the cell, this fundament