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Colesterolo alto non vuol dire necessariamente cardiopatia: le nuove sfide alle vecchie ipotesi
Le malattie cardiovascolari sono la principale causa di morte al mondo, rendendo la diagnosi e la valutazione del rischio una priorità assoluta. La teoria prevalente sul rischio di malattie cardiovascolari è l’ipotesi lipidica, che postula che l’aumento dell’apolipoproteina B (ApoB) e del colesterolo delle lipoproteine a bassa densità (LDL-C) siano fattori di rischio significativi che…
High cholesterol does not necessarily mean danger: the latest challenge of notions
Cardiovascular disease is the world’s leading cause of death, making diagnosis and risk assessment a high priority. The prevailing theory of cardiovascular disease risk is the lipid hypothesis, which posits that elevations in apolipoprotein B (ApoB) and low-density lipoprotein cholesterol (LDL-C) are significant risk factors that should be primary treatment targets. However, this new research…
Un nuovo meccanismo di produzione dei globuli rossi nell'anemia cronica: e il metabolismo dei grassi si fa avanti
I globuli rossi sono le cellule più abbondanti nel corpo. È noto da tempo che quando i globuli rossi si rompono o si verifica un’anemia dovuta a emorragia, l’ormone eritropoietina (EPO) aumenta, portando alla proliferazione di cellule immature (eritroblasti) che alla fine diventano globuli rossi, ripristinando così il numero di globuli rossi. Tuttavia, il modo in cui le “cellule staminali…
Lipoproteins and cardiovascular risk: how t manage
What are lipoproteins? Dietary lipids are digested within the gastrointestinal tract, following which they enter the intestinal mucosa to become chylomicrons, transporting triacylglycerols from food into the blood. Chylomicron breakdown in muscle or fat tissue yields chylomicron remnants for excretion by liver cells. Lipoproteins consist of lipids that are chemically attached to protein…
Alzheimer’s Disease: Increased Neurogenesis and Possible Disease Mechanisms Related to Neurogenesis
Alzheimer’s disease (AD) is a neurodegenerative disease for which there is no cure. Aging is the major contributing factor for the increased risk of developing AD. The risk of developing AD doubles every 5 years after the age of 65 and the disease affects more 30% of individuals over the... Alzheimer’s Disease: Increased Neurogenesis and Possible Disease Mechanisms Related to Neurogenesis
The Genetics of Alzheimer ’s Disease
Alzheimer’s disease (AD) is the most common form of age-related dementia and is characterized by progressive and insidious neurodegeneration of the central nervous system eventually leading to a gradual decline of cognitive function and dementia in affected individuals. The key neu- ... The Genetics of Alzheimer ’s Disease
