The Science Diaries of S. Sunkavally, p 654.

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The Science Diaries of S. Sunkavally, p 654.
Read this post and find out what are the main symptoms that will lead to cavities. Also, know about what precautions we can take before it gets more severe.
Juniper Publishers-Open Access Journal of Head Neck & Spine Surgery
Long-Term Results of Mandibular Reconstruction with Autogenous Bone Grafts and Oral Implants
Authored by Brajpal Singh Tyagi
Abstract
The reconstruction of mandibular defects after tumor resection is a challenging problems faced by Head and neck oncosurgeons. The mandible bone is known to play an important role in upper and lower airway protection and supporting of the musculature of tongue and dentition, as well as the muscles of floor of mouth, thus permitting the various physiologic acts of mastication, articulation, deglutition, and respiration. It is also known to provide for the contour of the lower face. Any interruption of mandible therefore produces both cosmetic and functional deformity. Resection of the mandible results in its deviation toward the resected side due to the unopposed pull of remaining muscles of mastication and scar formation. There is also limitations in movements of the jaw. We present a case of squamous cell carcinoma of left RMT & gingivo-buccal sulcus with mandibular bone invasion. He underwent hemimandibulectomy and ipsilateral radical neck dissection with post-operative radiotherapy in 2003. After 13 years of follow up he presented to us with complete resorption of the iliac crest graft with intact implant and no other symptomatic complaints. In review of literature regarding comparison of vascularized fibular flap and iliac crest flap for mandibular reconstruction it was found that functional and aesthetic results also showed that oral continence, social activities, and facial appearance rates of fibula flap are superior to iliac crest flap. The main complications of using iliac crest grafts are anaesthesia of the skin supplied by the lateral cutaneous nerve of the thigh, incisional hernias, and wound dehiscence in the thigh.
Keywords: Bone resorption; Iliac bone graft; Hemimandibulectomy
Case Report
We present a case of squamous cell carcinoma (SCC) of the oral cavity with mandibular infiltration in a 35 years old male patient requiring hemimandibulectomy, treated by surgical resection, therapeutic neck dissection and radiotherapy. Grafts from the iliac crest were used for augmentation of the defect, however it was associated with complete bone resorption after 13 years of surgery as a possible late complication (Figure 1-7).
Discussion
The mandible is one of the important parts of the body in terms of facial appearance and function. Vascularized free bone grafts have become the criterion standard in mandible reconstruction. Bone grafts from the iliac crest showed a significantly higher bone loss of 24.16% [1].
Functional and aesthetic results also showed that oral continence, social activities, and facial appearance rates of fibula flap were superior to iliac crest flap. Lower complication rates of fibula flap group may be associated with patient’s higher satisfaction rate. Both flaps are commonly used in mandibular reconstruction; however, many parameters including defect localization, defect size, presence of soft tissue defect should be considered [2].
Fibular flap was the flap of choice in total/subtotal mandibulectomy, but it does not appear preferable in hemimandibulectomy and/or in cases of segmental mandibulectomy, if compared with the iliac crest [3]. Nonvascularized fibular bone graft is as better as iliac crest for reconstruction of mandibular defects of optimal length [4].
The main complications of using iliac crest grafts are anaesthesia of the skin supplied by the lateral cutaneous nerve of the thigh, incisional hernias, wound dehiscence in the thigh, oronasal fistulas, wound dehiscence in the neck, infection by methicillin resistant Staphylococcus aureus in the thigh, and long-term disturbances of gait [5].
The main advantages of reconstruction using fibular flap method include the bicortical structure of the bone and its adaptability to conform to the mandibular contour. The only real disadvantage is the limited height of the bone graft, which does not allow alveolar ridge reconstruction. An implant-borne dental prosthesis can, however, generally be made for functional occlusal rehabilitation [6].
Comparing the quality of life associated with these two methods of mandibular reconstruction Patients with an iliac crest bone graft had significantly better chewing and swallowing. These findings suggest that reconstruction with the iliac crest had benefits in improved function (chewing, swallowing, and taste) rather than esthetics, donor site morbidity, or psychologic discomfort [7].
Conclusion
Both bone-grafting approaches are successful and reliable techniques, enabling implant placement in even highly atrophied alveolar ridges and with identical implant survival rates, although bone resorption differs.
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Linking Bone Metabolism & Density with Vitamin D Deficiency Research Paper Title Vitamin D Deficiency and Its Influence on Bone Metabolism and Density in a Brazilian Population of Healthy Men.
Cranioplasty after decompressive craniectomy: is there a rationale for an initial artificial bone-substitute implant? J Neurosurg 124:710–715, 2016 The complication rate for cranioplasty after decompressive craniectomy is higher than that after other neurosurgical procedures; aseptic bone resorption is the major long-term problem.
Beer Drinking May Reduce Risk of Kidney Stones
Beer Drinking May Reduce Risk of Kidney Stones
High intakes of calcium, potassium, and fluids have been shown to be associated with lowered risk of kidney stones.
In a study published in the American Journal of Epidermiology, researchers found that consumption of beer was associated with the decreased risk of kidney stones. For each bottle of beer consumed per day, the risk of kidney stones was reduced by 40 percent.
Researchers believe…
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Age-Related Changes in Bone Turnover and Differences between Men and Women
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Osteoporosis - Cellular and Molecular Effects of Estrogen on Bone
I. Introduction In 1941, Fuller Albright was the first to note the importance of estrogen in bone metabolism. Since then, estrogen deficiency has clearly been identified as the major factor contributing to involutional osteoporosis in women, and the effects of estrogen on the skeleton have been... Osteoporosis - Cellular and Molecular Effects of Estrogen on Bone