GENERAL CONSIDERATIONS* Take Home Message #COVID19 #booster #COVID_19 #BoosterJab Waning immunity (breakthrough infections reported) noted ~ 3-6 months after 2 doses. → Currently deployed vaccines given as third dose or 1st booster doses increase levels of neutralizing antibodies with higher protection against severe COVID-19, including variants alpha, beta, gamma, delta and omicron SARS-CoV-2 variants • Waning immunity ~3-4 months after 3rd or booster dose → A 4th dose or 2nd booster dose showed sustained T cell activation → Greater T cell mediated immune protection vs severe COVID and VOCs, thus, could be administered to special populations such as the immunocompromised, the elderly, those most vulnerable to severe COVID and those at very high risk of occupational exposure to COVID cases • We have improved our national vaccination coverage to ~74.5% of our target population of 90 million but still have to increase uptake among those who remain unvaccinated, those who still need to complete their 2nd dose, and for those eligible, the third dose and possibly, a 4th dose MPHS should continue to be practiced / adhered to as we still navigate through the COVID-19 Pandemic. https://www.instagram.com/p/CdsKHNKrOcB/?igshid=NGJjMDIxMWI=