A new COVID-19 variant is causing symptoms days before individuals test positive, posing challenges to containment efforts and highlighting
If you have a cold and test negative for COVID you are not in the clear. Tests take a while to turn positive. Meanwhile you are spreading COVID to family and friends. Mask up if you have any symptoms. This virus is just evil.
Pomegranate Medical is doing a silly 4/20 sale! get 20% off of 3M Aura respirators, rapid tests, mask tape, and more (no code needed; unclear what time zone it ends in, but to my knowledge, PM is based in the so-called "US")
💚 Covid PPE and Tests, by and for the Covid Cautious community 💚
Evolving peak SARS-CoV-2 loads relative to symptom onset may influence home-test timing | CIDRAP
Median SARS-CoV-2 viral loads, as measured by polymerase chain reaction cycle threshold and antigen concentrations, rose from symptom onset,
Median SARS-CoV-2 viral loads, as measured by polymerase chain reaction cycle threshold (Ct) and antigen concentrations, rose from symptom onset, peaking on the fourth or fifth day of symptoms. Estimated rapid antigen test sensitivity was 30.0% to 60.0% on the first day, 59.2% to 74.8% on the third, and 80.0% to 93.3% on the fourth.
Plain English:
Highest viral load is ~4-5 days into symptom onset, which means you're most likely to test positive about a week after an initial infection.
That also means that if you're IC/HR/etc. (or healthy & just don't want a disease that has a high chance of turning into long-term disability) and need to isolate from someone who's likely been exposed, the "quarantine" period should be at least 4-5 days, if not up to a week.
This has been the case for several years, not new, and corroborated by virologists and epidemiologists I've spoken to about their own protocol for infection avoidance.