"...is but a Dream within a Dream"

...I enjoy the fact you dont really care to know me. Now please, take your shoes off before walking into my blog.

[and-so-on]

[missw0rld]

Kali Úchis // Rolling Stone

[yuumei-art]

A repaint of my older work: Star Maker

The original 2019 version

[duplexide]

I don't know anything about YuGiOh but "Overworked" is the greatest card art they've ever done

[kaibutsu-kid]

Yeah that’s good but check out the original OCG art:

[vangoghcore]

by alexsamuelss

[catsoverloaded]

A black dragón floating above the clouds

[themediocrehuman]

So others need not squint to read “On March 11, 889 CE, 17 year-old Emperor Uda wrote:  ‘On the 6th day of the 2nd Month of the First Year of the Kampo era. Taking a moment of my free time, I wish to express my joy of the cat. It arrived by boat as a gift to the late Emperor, received from the hands of Minamoto no Kuwasahi.  The color of its fur is peerless. None could find the words to describe it, although one said it was reminiscent of the deepest ink. It has an air about it, similar to Kanno. Its length is 5 sun, and its height is 6 sun. I affixed a bow about its neck, but it did not remain for long. In rebellion, it narrows its eyes and extends its needles. It shows its back. When it lies down, it curls in a circle like a coin. you cannot see its feet. It’s as if it were a circular Bi disk. When it stands, its cry expresses profound loneliness, like a black dragon floating above the clouds. By nature, it stalks birds. It lowers its head and works its tail. It can extend its spine to raise its height by at least 2 sun. Its color allows it to disappear at night. I am convinced it is superior to all other cats.’”

[sbrown82]

Aevin Dugas on “The Doctors” with the world’s biggest afro!

[terrileeking]

In a few years, I hope my fro is as perfect as this...

[kaiserneko]

[korratea]

this video is so well done it deserves an oscar

[marvelousmichaelmidnight]

IN A ROW?

[laurakvstheworld]

oh my god the lipsync on this is so good

[captioningresource]

[Mako: You sucked that guys dick? Korra: Yeah…how do you think I knew that he… Mako: wait, but you said that you only had sex with three different guys! You never mentioned him! Korra: Because I never HAD sex with him! Mako: You sucked his dick! – Mako: What?! Something like 36? Korra: Lower your voice… Mako: Wait, what is that anyways, something like 36? Does that include me? Korra: ….You’re 37 Mako: I’m 37?! Korra: I’m going to class! Mako: uhh, my god! – Mako: 37! My girlfriend’s sucked 37 dicks! Bolin: In a row?]

[bloodbenderz]

world heritage post

[radiofreederry]

[swallowtailed]

[id: tweet by @ kibblesmith reading: “Me, totally safe, after spending four delightful hours in Jurassic Park's passenger pigeon and dodo sanctuary: "Fuck happened out here”” /end id]

[tsunamiwavesurfing]

[otherwindow]

Visually impaired tabletop merch!

[probablyjustfairyrpgideas]

SIGNAL BOOST

[phosphorescent-naidheachd]

[Image transcription: A tweet made by @DotsRPG that reads, “Help us spread the word about @DotsRPG! We are bringing #braille rulebooks, #rpgdice, and various gaming aids to the #blind and #visuallyimpaired. Head to our site, shapeways shop (bit.ly/2ugzieM) or thingiverse (bit.ly/2GfwEaH) to get your own braille #dice!”]

[o-kurwa]

[actionpackedjackson]

Booty shorts that say this

[saxifraga-x-urbium]

Two decades of Alzheimer's research may be based on deliberate fraud that has cost millions of lives

Last month, drug company Genentech reported on the first clinical trials of the drug crenezumab, a drug targeting amyloid proteins that form

fucking livid

[partisan-by-default]

Last month, drug company Genentech reported on the first clinical trials of the drug crenezumab, a drug targeting amyloid proteins that form sticky plaques in the brains of Alzheimer’s disease patients. The drug had been particularly effective in animal models, and the trial results were eagerly awaited as one of the most promising treatments in years. It did not work. “Crenezumab did not slow or prevent cognitive decline” in people with a predisposition toward Alzheimer’s.

Last year, the Food and Drug Administration (FDA) narrowly approved the use of Aduhelm, a new drug from Biogen that the company has priced so highly that it’s expected to drive up the price of Medicare for everyone in America, even those who never need this drug. Aduhelm was the first drug to be approved that fights the accumulation of those "amyloid plaques" in the brain. What makes the approval of the $56,000-a-dose drug so controversial is that while it does decrease plaques, it doesn’t actually slow Alzheimer’s. In fact, clinical trials were suspended in 2019 after the treatment showed “no clinical benefits.” (Which did not keep Biogen from seeking the drug’s approval or pricing it astronomically.)

Over the last two decades, Alzheimer’s drugs have been notable mostly for having a 99% failure rate in human trials. It’s not unusual for drugs that are effective in vitro and in animal models to turn out to be less than successful when used in humans, but Alzheimer’s has a record that makes the batting average in other areas look like Hall of Fame material.

And now we have a good idea of why. Because it looks like the original paper that established the amyloid plaque model as the foundation of Alzheimer’s research over the last 16 years might not just be wrong, but a deliberate fraud.

[saxifraga-x-urbium]

thanks for the text extraction, i was on my phone <3

[weird-ecologies]

Jesus christ

[fr0gt4nk]

👁

[fr0gt4nk]

tilt your phone and look at where my head should be 🖤

[terrileeking]

This gives off Dullahan energy...

[dankmemeuniversity]

[suitelikechocolate]

[buggachat]

Part 113 of my bakery “enemies” au!

taking a small break after this part because my wrist hurts <3 oops

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