[grantwilson]

good night to people who still use XD, people who grew up with undiagnosed mental illnesses, lesbians, my chemical romance fans, people in that awkward middle period between millennials and gen z, my high school english teacher, people who had braces in middle school, weird little girls, furries, michiganders, people who play support classes, and dr sydnee mcelroy

[bibivanna]

First Penny fanart✨

[streetkit]

it does suck that the government defunded PBS but it's also so fucking funny that now that they don't take uncle sam's slavery dollars they're running videos like "How america's foundation was built on genocide"

no more being polite about it fuck the USA

[sailermoon]

having unwashed hair will have you believing shit like i can’t be saved

[dogpuppy]

[systlin]

Getting down on my knees and thanking the humans who invented dishwashers and washing machines.

[ihonestlydontknowwhattocallthis]

InsNe that dishwashers are more efficient and easier than just washing them manually but they also use less water. It’s a win win situation

[systlin]

They ALSO sterilize dishes, due to operating at a far higher temperature than human hands could ever tolerate. It's a win every way.

[systlin]

Made this post about 15 minutes after the repair guy who fixed the pump on my dishwasher packed up his tools and left, as the dishwasher was whirring along doing my dishes from that morning.

He said the exact same thing, which I did not know before that, so spreading this knowledge.

[depsidase]

[parkerposey]

I feel like a horse with no name is probably the best song in the world. Not even my Favorite song just the best

[parkerposey]

He’s literally just telling it like it is

[going2hell4everythingbutbeingbi]

yes conservatism is on the rise yes tradwife content is as popular as ever yes pink jobs and blue jobs are fucking stupid BUT there is still such a big change in how straight women are talking about relationships online.

they're talking about how they're no longer interested in dating because their female friends treat them better than boyfriends do. they're realizing that being single is always better than being in a bad relationship. it's becoming a lot more normal and fun and hot for women to be single at any age. the women who have settled down with truly good men in truly happy relationships are encouraging other women to not take any shit because the right man won't need to be "trained". they're talking about how their mothers and grandmothers warned them to get a job and not get married, and they followed the advice.

tradwife content is performance. it's propaganda. there are so few women actually living that life. but we know for a fact that more women than ever are educated, working, and single. and all I see (admittedly in my woke ass algorithm) is women talking about how they're done settling for mediocre relationships. and I love it.

[priorwaltress]

all babies are baby gender. you dress them stupid, in pumpkins and teddy bear suits

[crabussy]

you are alive on a planet with insects and whales and diatoms and mycelium networks and puppies and your human friends. literally so awesome to be a living thing

[rimonoroni2]

i think we should be talking about the semi-recent advancements in cystic fibrosis treatment like all the time every day. there hasn’t been a drug like this since AZT medications for HIV infection it is truly fucking miraculous and very important

[rimonoroni2]

basically: cystic fibrosis is a genetic disease which makes the mucous a person generates extra sticky. it used to kill people in infancy, then with advancements in medical tech it killed people in young childhood, and until very recently cystic fibrosis patients could expect to live until about thirty years old with consistent painful lung infections and complications.

in 2019 the FDA approved a drug called trikafta (which is really three drugs in one) for cystic fibrosis treatment. what it essentially does is patch up the malfunctioning proteins that cause the extra sticky mucus. trikafta is effective on about 90% of cystic fibrosis patients.

people who had spent their entire lives in and out of hospitals, on and off of ventilators, suffering from pneumonia and sometimes treated through painful procedures like intubation took this drug, got out of bed, coughed up an entire lifetimes worth of mucus out of their lungs over the course of a few hours, breathed clearly for perhaps the first time in their lives, and now go on to live well into their seventies.

like isn’t that insane. isn’t that amazing. doesn’t that give you hope for the future of medical advancements and treatment. fuck. i think about it all the time……

[kittydesade]

There’s a WHAT.

For WHAT.

[sweetdreamspootypie]

It's been amazing!

My ward is the respiratory ward - CF is one of the things we specialize in.

Since this med came out we haven't had a SINGLE CF admission to the ward

There used to always be a CF patient spending a couple of months with us at a time

There's a man who is 23 years old who I was sure would not survive his next admission (aim saturations 85% is end stage lung disease)

There's a set of the local frequent flyers that we all know so well

Except

No we don't

On the CF specialist ward (with reasonable staff turnover)

Half the staff have probably never even seen a CF patient

They are going to live

[anartificialsatellite]

For the people asking "well how do we know people are living that long if it's so new????" Here's a page from the CF foundation about life expectancy.

Additionally, it should be noted that metrics like life expectancy are in no way a guarantee of... Anything. There are significant outlier CF patients who are at an advanced age now despite the odds due to a variety of different factors, having lived the majority of their lives before the development of modulators.

But the fact remains that the odds are better now than they have ever ever been before, by leaps and bounds. It isn't cured, and many patients still need significant treatment in addition to Trikafta, but it is so much better than anyone could have dreamed of twenty years ago, and that is a triumph.

[kittyoverlord]

Yes! My sister has a serious form of cf and finally is living a more comfortable and active life. She was also part of many of the clinical trials leading to these breakthroughs due to the nature of her cf. It's been very exciting to see.

[naamahdarling]

That's absolutely incredible. Don't get me wrong. It's miraculous from a clinical standpoint. But, uhh. Not to be a downer but I need people to see this so they stay angry and stay real about what medical breakthroughs actually mean for patients. When I call something "survival gatekeeping", this is what I mean:

That is per month with the most common coupon people are likely to use.

But don't worry, there's grants and patient assistance programs you can apply for. 🤞🫠 Most people in high income countries like the USA can get it "covered" through insurance for fewer thousands of dollars. Or even less if your insurance is good or the manufacturer likes how poor and/or on Medicaid you are! A good social worker will help you with the process, and make sure your yearly reapplications and PAs are done a little early so they have time to think about it before you run out. Jesus Christ.

NEVER look at something like this and navigate away feeling better about things without asking how much it costs and who can get it. NEVER. It isn't revolutionary until poor people can access it without a struggle.

[bean-pronounced-bawn]

I can't find the post but there's this one post that's like "aging is less than 1% as terrifying as whatever the fuck is going on with people desperately trying not to age"

That but with weight.

Getting or being fat is less than 1% as terrifying as whatever the fuck is going on with people desperately trying to not be fat.

[kyssimmee]

starlight and trixie comic

[kyssimmee]

i'm breaking the author's silence to address these tags directly, because i've seen similar responses a few times. your context is part of you. you like your favorite band because you found them somehow. you speak the languages you speak because somebody else taught you. you feel the way you feel because you have memories and experiences. shaving off pieces of yourself will not reveal a truth at the center, and will only make you feel less like a person worth being. you will never shed your context or influences, anymore than you will ever become younger or undrink a glass of water. but you are free to create as much additional context as you like. build yourself outward instead of digging for yourself at the center. trying 100 new things will give you 100 more data points on what you like, don't like, think, believe, feel. it might begin to reveal an image of yourself that you can recognize, respect, and love. your life is not an object to be kept clean, it is an ongoing action that you get to control. also that's starlight glimmer not rarity.

[krablord]

for Some reason I expected this post from the official Ripleys Aquarium to just be a ShitPost about gay fish

but its??

actual fun information?? about fish that do not fall into normal sex expectations. Neat

[headspace-hotel]

I'm dead convinced that a significant portion of AI companies' revenue is spent paying off every major media outlet NOT to point out all the obvious problems with it + creating legions of bots and bullshit articles online to hype AI up

cause like. apart from the (potential) exception of writing code, there is not really anything useful that a Large Language Model can do.

it imitates patterns in the text that it takes in

that's fundamentally how it works

if a Large Language Model can produce text that looks like something a human created, that doesn't mean it can do a human's job, it means that the paperwork/plan/document it's being used to create no longer fucking means anything

[headspace-hotel]

Yes, haha funny, the AI is bamboozled by spelling, but seriously: I asked Google the same question 5 different times just now, and not only did I get 5 incorrect answers, I got 5 completely different incorrect answers.

The fact that they're different every time demonstrates just how much of an LLM's output is up to random chance. This is how LLMs imitate human language: each stage of constructing the text has built-in randomness, just like how human language has variation and flexibility.

This is my problem with using these things in the workplace. Like, imagine you're using an LLM to fill out a report of an accident that happened, or to write dietary recommendations for a patient, or to give feedback on a paper a student wrote...really anything you can think of.

Even if the LLM-generated text doesn't say anything technically flat-out wrong, the words and details are still randomized instead of being chosen by you for an actual reason.

Using an LLM for these tasks means it doesn't matter to you exactly what you write, what words you use, what details you include, or what meaning it has, just that it looks like you wrote something.

[disheveled-notion]

I’ll also point out that it’s also not good for writing code for the exact same reasons. Part of working on a codebase is working within established coding patterns and architectural decisions so that other people can easily navigate it. If every single module is written completely differently than, inevitably, when some human has to go in there and fix a bug it becomes much harder since every file is written completely different even if they handle the same problem-space. If one module is completely object oriented and uses class instantiation for everything and another that solves a similar problem is functional programming and relies entirely on pure functions then trying to figure out how they are supposed to work together is infinitely harder than just using one model.

[queer-here-and-in-fear]

shorthands for dumbassery that i have grown to love deeply

"how dare you say we piss on the poor" in response to someone misinterpreting your post

"_ isnt gonna fuck you" for suck up behavior

"woah. should we tell everyone? should we throw a party?" for who the fuck cares

"and what if the world was made of pudding" for when would this ever matter.

"and sharks are smooth both ways" for a group of people heatedly arguing with 1 guy who is fucking with them all

".. but its about a witch in the alps finding her lost cat" for someone trying to sanitize something to the point of absurdity

[queer-here-and-in-fear]

this is prime proof that this ENTIRE WEBSITE is autistic because nowhere else would a no tags post that's just an informative list about slang get this much traction.

[queer-here-and-in-fear]

anyway more addittions

“30-50 wild hogs” for someone making ABSURD excuses for violence.

“what were YOU doing at the devils sacrament” for how do you know that without being a part of it.

“anyone in this thread smoke weed” for the shit you people are saying is so off topic this might as well be a general discussion forum

“dogs are boys and cats are girls” for ooh ur mindset did not grow past 4th grade, huh

“color theory in a childrens hospital” for bending over backwards to not agree that YEA, that thing Came Off Weird

“you are a tar pit” for someone finding any reason to respond with outrage.

“is the __ in the room with us right now?” for I Don’t Think That’s Real.

“bean soup? im allergic to beans!” for ik this doesn’t work for you, but that’s not a flaw. not everything can be for you.

“people irl: hey man hows it going” for this will Never Matter irl