Esto lo encontré en Queens Medical Office P.C. #COVID-19 #tratamientos (at Queens, New York) https://www.instagram.com/p/B_AVELmHIow/?igshid=17jwrlbfc8udk
Esto lo encontré en Queens Medical Office P.C. #COVID-19 #tratamientos (at Queens, New York) https://www.instagram.com/p/B_AVELmHIow/?igshid=1aueob6uwc5uq
At the moment there is no medication that is specific for treating COVID-19 but yes, there are talks of drugs that have been repurpose for treating SARS-CoV2, the virus that causes COVID-19. Which are those drugs and how they work? Do they promise any hope for stopping this virus?
WHO has started a trial program with the purpose to analyze different medications and their effect on the virus. The medications that made the cut are:
Remdesivir - the medication was mainly created to treat Ebola, but it has been noticed in labs that it can treat SARS and MERS, two coronavirus that behave similar to COVID-19. This medication works by inhibiting the enzyme RNA-Polymerase. With this enzyme out, the virus can’t replicate its RNA. It has been noticed that it’s effectiveness is during mild to moderate signs and symptoms of COVID-19.
Chloroquine and hydroxychloroquine - an antimalarial medication that reduces acidity in an endosome. An endosome is a vesicle that our cells use as transportation. Chloroquine and hydroxychloroquine prevents COVID-19 from using this method. There are two problems to this medication: first COVID-19 uses ACE-2 receptors as a way of propagation and not endosomes. Second, the dose to make it work is 600 to 800 mg for 10 days. The safe dose is 5 mg/kg/day, it is unknown if this high dose for 10 days causes problem. The French Doctor Didier Raoult, MD, PhD claims that hydroxychloroquine plus the antibiotic azytromicin cures COVID-19 and drops the viral load in a short period of time. Hydroxychloroquine is less toxic than chloroquine. This medication is used for LUPUS, Rheumatoid arthritis and other autoimmune disorders.
Ritonavir/Lopinavir - known in USA as Kaletra, this HIV medication prevents proteins from being transformed into smaller units that later will be use for translation and replication of the virus. It has been noticed that this medication works better at the beginning stage of the virus.
Ritonavir/Lopinavir/Interferon Beta - this combination seems more promising as long as there is no severe symptoms of inflammation. In that case, interferon could cause more damage than help. The interferon beta is produced by Cuba.
ACEI’s and Angiotensin Converting Enzyme Receptors Blockers (ARB) - Angiotensin Converting Enzyme Inhibitors are meds for high blood pressure, kidney problems, or coronary problems. This medication is not being used by WHO in the trial but it is worth mentioning. SARSCOV-2 uses ACE2 to enter the body and it was hypothesized that blocking this receptors would help stop the virus but it has been noticed that the body increases the production of ACE receptors facilitating the propagation of the virus. If you or anyone you know uses any of the medications, please do not stop taking them. Please, self-quarantine and observe all the recommendations such as using a face mask, and keeping a 1.5 meter (6 feet) distance.
Tocilizumab or Sarilumab - It is not being used in the trial by WHO but, again, it is worth mentioning. This medication is an immunosuppressant and its purpose is to reduce IL-6 (interleukin 6) and prevent a cytokine storm in some patients. Some patients’ immune system go crazy before SARSCOV-2 and can cause more harm than help, therefore the medication.
Ivermectin - is an antiparasitic medicine that seems to clear the virus within 48 hours. Studies were done in vitro. Is not on the WHO list of meds in trial.
Favipiravir - an antiviral medication with a wide spectrum of action against different virus such as influenza, and ebola. This medication inhibits the replication of a virus and lowers viral load. China is sending it to Turkey while Japan has entered in talks with USA and other countries. This medicine is not part of WHO's trial.
In summary, there is no drug available. It takes time to develop and test one. At the moment, the medical community is repurposing some drugs and reporting to WHO in order to determine a best course of action. Therefore, the best action is, isolate, wash your hands, use a face mask, and keep a distance of 6 feet (1.5 meters).
REFERENCES:
WHO launches global megatrial of the four most promising coronavirus treatments. By Kai Kupferschmidt, Jon Cohen. AAAS. Science. March 22, 2020. Accessed April 4th, 2020.
Chronic use of heart disease medications may increase the risk of severe COVID-19. By Hannah Balfour. Drug Target Review. 24 March 2020. Accessed April 4th, 2020.
Treatments for COVID-19: Drugs being tested against the coronavirus. Live Science.
Hydroxychloroquine: Possible COVID Drug Can Be Toxic to Retinas. Brianne N Hobbs,OD; Kalia M Osmotherly, OD. 2 April 2020. Accessed April 4th, 2020.
‘Drug development is a long, long process’: pharma CEO in Italy sounds a note of caution on Covid-19. By Elizabeth Cooney. 26 March 2020. Accessed April 4th, 2020.
Coronavirus: What is Ivermectin and how it works. AS.COM. 4 April 2020.
Japan Is Racing to Test a Drug to Treat Covid-19. By Joshua Hunt. Wired.com 4 April 2020.
CoVID-19: More Hydroxychloroquine data from France, more questions. Veronique Duqueroy. Hospitalist. 1 April 2020.
Chloroquine and Hydroxychloroquine as available weapons to fight COVID-19. International Journal of Antimicrobial Agents.
Nasal irrigation (NI) is an Ayurveda therapy which the western world borrowed in the 19th century.
Its purpose is prevention of upper respiratory tract infections or to “alleviate” sinusitis, rhinitis, and postnasal drip among other conditions. My first experience with NI was around 2004. I was suffering a terrible case of sinusitis and I went to Lynn Sisters in Bowery Street, New York. I was expecting some Chinese herbal formula to drink but I was offered a Neti pot with a few small pouches similar to the size of ketchup take out. The ingredient was either Jin Yin Hua (Flos Lonicera aka Honeysuckle) or Pu Gong Yin (Herba Taraxaci aka Dandelion). I am inclined for the latter. I got home, and proceeded to do as instructed... OMG! A stingy and burning feeling took over for 1 or 2 seconds but for me, it felt like 5 mins. After several flushes a day for a week, my sinus problem was gone. I don't suffer of that horrible sinus problem since then.
How it works and How to make your own solution
NI works by dislodging mucous and eliminating or reducing prostaglandins and leukotrienes (proinflammatory molecules) and antigens that elicit allergic reactions while increasing lysosome and lactoferrin concentrations. The mineral content of saline solution used for NI assists in cleaning debris while supporting anti-inflammatory properties and maintaining a healthy lining in the upper respiratory tract where zinc functions are supported. The pH of the solution should be between 6.2 to 8.4 which has been shown to be safe for the integrity of the nasal and sinus lining and its functions. Some experts recommend Ringer’s Lactate (same as Hartmann’s solution). You can create your own by using distilled water and adding some mineral content that can mimic seawater minerals. Do not use Kosher salt or table salt.
Solution with a concentration of 5.4% or more can cause pain, blockage, and rhinorrhea.
Which bacteria or viruses attack the Upper Respiratory Tract
The question to ask is which bacteria or virus can invade the upper respiratory tract causing rhinitis, sinusitis and other upper respiratory tract infections? The answer is simple, in its majority, the culprit is a virus. Coronavirus is well known to cause common cold, sinusitis, and rhinitis. Like I mentioned on another post, H-CoV that can cause the previous ailments are HKU1, 229E, and OC43. Rhinoviruses, parainfluenza viruses, adenoviruses, respiratory syncytial virus, influenza viruses, and adenoviruses among others can enter and lodge and disrupt the upper respiratory apparatus eliciting signs and symptoms such as runny nose, and inflammation, just to point out two signs and symptoms.
A Few Last Words
Nasal irrigation should be part of your daily hygiene as it is brushing and flossing.
Your solution should be lukewarm, mimic the ocean’s water if possible.
Yes, you can add some baking soda.
Irrigation works best when in low concentrations, in other words more salt doesn't make it better.
Clean your neti pot.
Drink plenty of water, rest, eat healthy, and take your daily vitamin/mineral supplement.
Biography:
Emmanuel Arroyo is a Licensed Acupuncturist, certified aromatherapist and iridologist in the State of New York. Has a Master in Oriental Medicine and is a member of NCCAOM, and ASNY.
Emmanuel Arroyo wrote an essay which was featured in JASA in Fall 2019. The essay was on Ego, ID, and Defense Mechanisms and Chinese Medicine. Emmanuel Arroyo has appeared on TV in two occasions and once in radio.
Contact Information:
If you or a love one suffers of sinus problems you can set up an appointment by calling, texting or emailing...
(1) Prinicipi, Nicola and Esposito, Susanna. Nasal Irrigation: An Imprecisely Defined Medical Procedure. Int J Environ Res Public Health. 2017 May;14(5).
(2) Purushothama V. Dasaraju, Chien Liu. Chapter 93 Infections of the Respiratory System. The University of Texas Medical Branch at Galveston. 1986.
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Quercetina y Bromelina ¿Qué son?, ¿qué hacen?, ¿cómo y cuándo ingerirlas? #quercetina #bromelina #suplementos #flavonoides #salud #iridologia #aromaterapia #medicinanatural #medicinachina #newyorkcity #Queens #acupuntura (at New York, New York) https://www.instagram.com/p/B9UOBCVn7pP/?igshid=10ok88ylcmk39
Coronavirus, discovered in 1960,[1] is a positive-sense RNA virus that mainly targets the upper respiratory tract except for SARS which causes upper and lower tract infections and gastroenteritis. A positive-sense RNA is also known as positive-strand RNA virus[2]. The name is given due to its single strand of RNA while positive refers to genetic information carried for replication. Coronavirus causes the common cold, except for SARS and MERS, and now COVID-19.
Coronavirus (CoV) belong to the order of Nidovirales, which includes Coronaviridae, Arteriviridae, and Roniviridae families. CoV is divided into two subfamilies, CoV and the second subfamily Torovirinae. CoV has a cap (let’s call it head) which carries all the information needed for replication, while the tail has all the information related with structure and functions. The tail contains four important structures, S (spike), M (membrane), E (envelope), and N (nucleocapsid) proteins. The S structure is the one that attaches to the host cell receptors. The M structure gives the shape/form. The E structure is important for assembly and release of the virus; some virus need the M structure for pathogenesis. Structure N facilitates binding and affinity to viral or non-viral RNA. Both N and M work synergistically and facilitate replication and diffusion of the virus in the host.[3]
For binding, CoV mainly uses aminopeptidase as receptors except SARS and NL63 that use angiotensin-converting enzyme and MERS uses dipeptidyl-peptidase-4.
The Wuhan-coronavirus is new and is identified as 2019-nCoV, also known as COVID-19. COVID-19 stands for COronaVIrus Disease and is the full blown manifestation of SARS-COV2. SARS-CoV2 is a mutated coronavirus where the S structure attaches to Angiotensin Converting Enzyme 2 (ACE2) and it contains two subunits attaching to furin which makes it similar to Ebola, HIV, and avian influenza virus.[4] Furin is a protease found inside a cell and is known as Proprotein Convertase (PC) which develops the synthesis of prohormones, neurotrophic factors, serum proteins, regulation of hair, teeth, sweat glands, embryogenesis, calcium, pH, and interesting enough it also determines how virulent or infectious a bacteria or virus will be. It determines cancer aggressiveness and creates amyloid which are a key of Alzheimer’s.[5] Furin also regulates Insulin Growth Factor in upper respiratory tract and colon.
SARS-CoV2 Spike structure is genetically similar to the Spike structure to a Guangdong pangolin, while its genetic sequence is similar to a bat betacoronavirus of the genus sarbecovirus and is namedRaTG13. SARS-CoV2 has an ancestor which has been labeled Type-S. This ancestor is less aggressive and propagates slower. The aggressive SARS-CoV2 is dubbed Type-L and it is unknown if the Type-S mutation to Type-L occurred in the animal or in the human.
How many human coronaviruses are known?[6],[7]
In the past CoV was classified according to the immune reaction, hence the Alpha, Beta, Delta, and Gamma nomenclature.
There are seven known human coronaviruses:
1. Alpha coronavirus:
a. 229E (1960) – causes common cold
b. NL63 (2004) – causes croup hence it targets kids. Similar genome to 229E. Uses angiotensin converting enzyme. Is a recombination of PEDV. Hast two variants.
2. Beta coronavirus:
a. OC43 (1960) – causes common cold. It is believed it evolved from bovine CoV.
b. HKU1(2005)
c. SARS-CoV (2003) uses angiotensin converting enzyme 2.
d. MERS-CoV (2012)
3. SARS-COV2 - uses Angiotensin Converting Enzyme 2, the Spike structure has subunits attaching to furin.
There is no vaccine for any, the only vaccine created was for SARS and it was an attenuated virus.
China has been using a drug produced in Cuba known as Alpha Interferon which intention was for HIV, Human Papilloma Virus, Hepatitis B and C, and some cancers. This medication has been used successfully and China claims that it has cured 1,500 cases as of February.[8] China uses Kaletra or Aluvia (liponavir and ritonavir) with Rivabirin which are medications for HIV and Hepatitis. The use of HIV meds and Tamiflu is another cocktail in use. The medication for malaria, Cloquonine, is also used for COVID-19. Another medication added to the cocktail is Thymosin, a medication that assists in the maturation of T-cells.
Do Animals get Coronavirus?
Yes, animals do get infected with coronavirus, but it is difficult for getting infected with HUMAN coronaviruses. Some of the coronaviruses in animal are the following:
o Virus: Adenovirus Type 2, Avian influenza A, Canine parvovirus, Enterovirus D68, Feline Panleukopenia, Hepatitis A, Hepatitis B, Hepatitis C, Herpes simplex type 2, Human coronavirus, Human immunodeficiency virus type 1, Influenza A, Influenza B, Measles, MERS-CoV, Norovirus, Poliovirus type 1, Respiratory syncytial (RSV), Rhinovirus, Rotavirus, SARS-CoV.
It is important to point that CoV killed by Clorox are SARS, MERS and that H-CoV mentioned by Lysol® and Clorox®are the ones that cause common cold. [12]
China and SARS, A Lesson on How to Treat
When SARS (Severe Acute Respiratory Syndrome) hit China the treatment response was multifactorial; China used an integrated approach of Chinese medicine and Western medicine. This integrated approach consisted on nutritional support, Chinese herbal medicine, and a regime of oxygen supplementation, corticosteroids (methylprednisolone), antibiotics (azithromycin, cefotaxime, amoxycillin-clavulanic acid, ciprofloxacin, demethylvancomycin), immunoglobulin, and thymosin. The medications used were according to severity and symptomatology. From the western approach we can determine that healthy eating habits are important. The use of antibacterial, corticosteroids, and thymosin is evidence that herbal, vitamins, mineral, and amino acid supplementation with antibacterial, anti-inflammatory, analgesic, immunomodulatory properties are paramount as prophylactic measures.
From a Traditional Chinese Medicine (TCM) perspective SARS was diagnosed as Wen Yi Bing or Warm Pestilential Disease.[13] The differential diagnosis used was Four Divisions (Wei-Qi, Ying-Qi, Xue, Yuan) and the Triple Heater or San Jiao. The aim of the Chinese herbal formulas was to expel pathogen, clear heat, and dissolve dampness therefore the herbal formulas used back in 2003 for SARS were the following:
· San Ren Tang (Three-Nut decoction) + Shen Jiang San (Ascending-Descending Powder)
o Ingredients: Xing Ren (Semen Pruni Armeniacae), Bai Dou Kou (Fructus Cardamomi Rotundi), Sheng Yi Yi Ren (Semen Coicis), Hua Shi (Talcum), Tong Cao (Medulla Tetrapanacis Papyriferi), Zhu Ye, (Herba Lophateri Gracilis), Hou Po Hua (Flos Magnolia Officinalis), Fa Ban Xia (Rhizoma Pinelliae Ternatae), Jiang Can (Bombyx Batricatus), Chan Yi or Chan Tui (Periostracum Cicadae), Pian Jiang Huang (Rhizoma Curcuma Longae), Cang Zhu (Rhizoma Atractylodis), Huang Qin (Radix Scutellariae Baicalensis).
· Yin Qiao San (Honeysuckle and Forsythia Powder) + Ma Xing Shi Gan Tang (Ephedra, Apricot Kernel, Gypsum, and Licorice Decoction) + Sheng Jiang San (Ascending-Descending Powder).
o Ingredients: Sheng Ma Huang (Herba Ephedrae), Xing Ren (Semen Pruni Armeniacae), Sheng Shi Gao (Gypsum), Zhi Gan Cao (Radix Glycyrrhizae Praeparatae) Jiang Can (Bombyx Batrycarius), Chan Yi or Chan Tui (Periostracum Cicadae), Bo He (Herba Menthae), Lian Qiao (Fructus Forsythiae Suspensae), Jin Yin Hua (Flos Lonicerae), Huang Qin (Radix Scutellariae Baicallensis), Lu Gen (Rhizoma Phragmitis Communis) Shen yi Yi Ren (Semen Coicis), Pain Jiang Huang (Rhizoma Curcumae Longae).
· Gan Lu Xiao Du Dan (Sweet Dew Special Pill to Eliminate Toxin)
o Ingredients: Sheng Shi Gao (Gypsum), Xing Ren (Semen Prunus Armeniacae), Hua Shi (Talcum), Huang Qin (Radix Scutellariae Baicallensis), Chai Hu (Radix Bupleuri), Yin Chen Hao (Herba Atemisae Capillaris), Shi Chang Pu (Rhizima Acori Graminei), Fa Ban Xia (Rhizoma Pinelliae Ternatae), Hu Zhang (Radix et Rhizoma Polygoni Cuspidati), Bai Dou Kou (Frucuts Cardamomi Rotundi), Jiang Can (Bombyx Batricatus), Chan Yi or Chan Tui (Periostracum Cicadae), Cang Zhu (Rhizoma Atractylodis), Jiang Huang (Rhizoma Curcuma Longae).
· Hao Qin Qing Dan Tang (Artemisia Annua and Scutellaria Decoction to Clear Gallbladder)
o Ingredients: Qing Hao (Herba Artemisiae Apiaceae), Zhu Ye (Herba Lophateri Gracilis), Fa Ban Xia (Rhizoma Pinealliae Ternatae), Chi Fu Ling (Sclerotium Poriae Cocos Rubrae), Huang Qin (Radix Scutellaria Baicalensis), Chen Pi (Pericarpium Citri Reticulatae), Xing Ren (Semen Pruni Armeniacae), Sheng yi Yi ren (Semen Coicis), Hua Shi (Talcum), Qing Dai (Indigo Pulverata Levis), Cang Zhu (Rhizoma Atractylodis), Yu Jin (Tuber Curcumae).
· Wu Hu Tang (Five Tiger Decoction) + Ting Li Da Zao Xie Fei Tang (Descurainia and Jujuba Decoction to Drain the Lungs) + Lian Po Yin (Coptis and Magnolia Bark Decoction)
o Ingredients: Zhi Ma huang (Herba Ephedrae), Sheng Shi Gao (Gypsum), Xing Ren (Semen Pruni Armeniacae), Zhi Gan Cao (Radix Glycyrrhizae Praeparatae), Lu Cha (Folium Thea Sinensis), Ting Li Zi (Semen Tinglizi), Chuan Lian Zi (Fructus Meliae Toosendan), Hou Po or Chuan Po (Cortex Magnolia Officinalis), Zhi Shi (Fructus Aurantii Immaturus), Shan Zhi Zi (Fructus Gardenia Jasminoidis), Dan Dou Chi (Semen Sojae Praeparatum), Shi Chang Pu (Rhizoma Acori Graminei), Lu Gen (Rhizoma Phragmitis Communis), Fa Ban Xia (Rhizoma Pineallia Ternatae), Jie Geng (Radix Platycodonis).
· Qing Ying Tang (Clear the Nutritive level Decoction) + Sheng Mai Yin (Generate the Pulse Decoction)
o Ingredients: Shui Niu Jiao (Cornu Bubali), Sheng Di Huang (Radix Rehmanniae Glutinosae), Xuan Shen (Radix Scrophulariae Ningpoensis), Jin Yin Hua (Flos Lonicerae Japonica), Xi Yang Shen (Radix Panacis Quinquifolii), Mai Men Dong (Tuber Ophiopogonis Japonici), Shan Yu Rou (Fructus Corni Officinalis)
It is important to remind the aforementioned formulas are used according to pattern discrimination, but a quick analysis of the herbs used will show some herbs or classification of herbs are used frequently in all the formulas. They are herbs that clear heat, drain dampness, transform phlegm, and regulate Lung Qi. The most used herbs in these formulas are Huang Qin, Pian Jiang Huang, Bai Dou Kou, Jin Yin Hua, Lu Gen, Ban Lan Gen, Fa Ban Xia, Chan yi or Chan Tui, Yi Yi Ren, Xing Ren, Shi Gao, and Hua Shi. Once heat passes to the Ying or Xue level damage to Qi and Yin has taken place manifesting as diarrhea, headaches, and/or shaking/tremors. From a six-division perspective Tai Yin, Yang Ming, Jue Yin damage has taken place once the pathogen surpasses the Tai Yang level. The SARS is a Phlegm-Heat pathogen that causes shortness of breath, fatigue, and can cause delirium, collapse or fainting, and bleeding which are quite like the presentation of COVID-19. This experience provides us with a diagnosis of a Wen Bing Phlegm-Damp-Heat pathogen for COVID-19.
CoVid-2019 Signs and Symptoms[14]
Some of the signs and symptoms reported are:
Flu like presentation:
· Runny nose
· Nasal congestion
· Low grade fever
· Body aches
Pneumonia presentation:
· Shortness of breath
· Chest tightness
· Wheezing
· Cough
· Fatigue
· High fever
· Dry mouth
· Bitter taste
Signs and Symptoms, Chinese Medicine and CoVid-19
In China, COVID-19 is diagnosed as phlegm-damp heat pestilential qi. The tongue has a thick yellow fur and a red and wet body. The signs and symptoms are runny nose, sneezing, sore throat, fever, and difficulty breathing leading, wheezing, chest tightness, fatigue, dry mouth, bitter taste, and diarrhea.[15],[16],[17] The main feature is difficulty breathing and x-ray or CT-Scan showing bilateral lung ‘infiltrates' or 'ground-glass opacities.' These opacities are pockets filled with thick mucus which prevents breathing. It takes 2 to 14 days to show any sign and symptoms, but it has been reported cases were takes longer to show any sign and symptoms. COVID-19 starts as common cold, then switches to flu like symptoms and then pneumonia. It is calculated that 2 people can infect 2.5 people a day, the infection increase rate is 53% per day.[18] The mortality rate is low but has a high infection rate. In the Hubei Provincial Hospital of Integrated Traditional Chinese Medicine and Western Medicine COVID-19 has been divided into 4 Stages: Prevention (this stage is common cold), Influenza, Pneumonia, and Recovery Stage. Each Stage has a set of herbal formulas and pattern discrimination. Below I have summarized their recommendations, for detail information please read How COVID-19 (2019-nCoV) is Currently Treated in China with TCM by John K Chen.
· Prevention Stage: Diagnosis is damp cold in the Lung and the recommended formula is a modified Yu Pi Feng San.
· Influenza Stage: The diagnosis is Exterior Wind-Cold invasion, Toxic heat invading the Lung, or Damp Cold in the Lung, The formulas recommended are Ge Gen Tang (Kudzu Decoction), Chai Ge Jie Ji Tang (Bupleurum and Kudzu Decoction), Huo Xiang Zhen Qi San, Yin Qiao San (Honey Suckle and Forsythia Powder), Qing Wei Bai Du San (Clear Epidemics and Overcome Pathogenic Influences Powder).
· Pneumonia Stage: Is diagnosed as Shao Yang Syndrome with Damp, Damp-Heat Distressing the Lung, Toxic Stagnation Hampering the Lung or Hot Type Closed Disorder with Devastated Yang. The formulas recommended are Xiao Chai Hu Tang (Minor Bupleurum Decoction), San Ren Tang (Three-Nut Decoction), Gan Lu Xiao Du Dan (Sweet Dew Special Pill to Eliminate Toxins), Ma Xing Yi Gan Tang (Ephedra, Apricot Kernel, Coicis, and Licorice Decoction), Xiao Xian Xiong Tang (Minor Sinking into the Chest Decoction), Cao Guo Zhi Mu Tang (Tsaoko and Anemarrhena Decoction), Bai Hu Jia Ren Shen Tang (White Tiger plus Ginseng Decoction), Si Tu Tang (Four Wild Decoction), Si Ni Jia Ren Shen Tang (Frigid Extremities Decoction Plus Ginseng), An Gong Niu Huang Wan (Calm the Palace Pill with Cattle Gallstone), Zi Xue San (Purple Snow Powder).
· Recovery Stage: Qi and Yin Deficiency with closed collaterals. Recommended formula is Sha Shen Mai Dong Tang (Glehnia and Ophiopogonis Decoction).
The herbs that were used the most were Huang Qin, Huang Lian, Ma Huang, Bai Zhu, Bai Dou Kou, Jin Yin Hua, Chen Pi, Fa Ban Xia, Yi Yi Ren, Xing Ren, Gua Lou, Sheng Jiang, Dan Zhu Ye, and Zhi Mu. An analysis of these herbs shows Heat-Pathogen invading the Lung and damaging fluids causing phlegm, chest tightness and shortness of breath which in normal parlance is pneumonia. The heat damages the Spleen which generate dampness and disturbs digestion; during this stage the pathogen causes what we know as enteritis leading to diarrhea. As the Heat-Pathogen advances, the person collapses. Is during this state that the person has entered the Jue Yin level, has damaged Shao Yin and a diagnosis of Closed Heat-Type Collapse with Devastated Yang is given or as John Chen calls it Closed Interior and Abandoned Exterior. Heat shuts the orifices (consciousness) and enters the Pericardium/Heart. The formulas have the purpose of eliminating the pathogen. Plants bioactive compounds are their antigen, their immune system developed to fight pests and it is theses bioactive compounds that have healing properties.
Herbs that are effective against the CoV are rich in triterpene glycosides such as saikosaponins A, B2,C, and D or phenolic compounds. The herbs are the followings:[19],[20]
· Radix Bupleurum (Chai hu) – early stage infection of 229E
· Radix Scrophularia (Xuan shen) -early stage infection of 229E
· Isatidis indigotica (Ban lan gen, Cao da qing, Ma lan) – SARS
· Torreya nucifera or Semen Torreyae (Fei zi) – SARS
· Radix Dioscorea spp – SARS
As precaution you might use Gan mao ling and Yu Ping Feng San. The ingredients in Gan mao ling are gang mei geng or wan dian jin (Radix Iicis asprellae), wu zhu he (Folium Evodia), shan pu he or wu zhi gan (Folium viticis) ban lan gen (Radix Isatidis), ju hua (Flos Chrysanthemum), jin Yinn hua (Flos Lonicerae), and bo he (Herba Mentha). This formula clears heat, toxins, and opens the chest. Ban lan gen and jin Yinn hua have immunomodulatory properties.[21]
As reported by R. K. Ganjhu et al:
Also, if we glance through the different plant preparations reported in this review, we will notice that most of them represent extracts made of more than one plant species. That draws our attention to the uniqueness of each plant species and their constituents, which together with other plants make a formulation effective in treating a plethora of viral infections. An in-depth analysis of such formulations along with a bio-activity guided isolation of active components shall definitely give a better idea about the active principles responsible for a varied antiviral action. Research in this direction is in progress as collated from different papers. There are ample reports revealing immunomodulatory properties of many plant extracts mediated through induction and release of pro-inflammatory cytokines, IL-6 and IL-12. IL-12, produced by activated monocytes/macrophages and dendritic cells, stimulate cell-mediated immunity to release IFN-c, promote Th-1 responses, and enhance CD8 + cytotoxic T cell activity, thereby playing a pivotal role in controlling viral replication. There also exist evidence on IL-6 production by macrophages in response to virus infections, in addition to reports justifying its role in clearing viral infection from the physiological system.[22]
I would like to quote John Chen:
From the Western Han Dynasty to the end of the Qing Dynasty, at least 321 large-scale plagues occurred in China. Chinese medicine has served to wage life-and-death battles against various plague consistently through time and has successfully contained the spread of epidemics in a limited area and time. There has never been a similar tragedy in China’s history, such as the Spanish flu or the Black Death in Europe. These are examples of global plagues that killed tens of millions of people.
In the Chinese history, whenever a plague is rampant, Chinese medicine practitioners are always on the front lines to battle the disease. Many survived with the help of Chinese Medicine; so in this fight with the insidious and novel Coronavirus, Chinese Medicine once again should take a primary role in effective treatment and must not be absent in action!
Essential Oils and Viruses
Hinokitiol is an essential oil of from the wood of Cupressacea trees. This oil, when it enters in contact with zinc it elicits the interchange of zinc ions and stops viral replication, in this instance SARS-CoV, and inhibits lung cancer cell growth.[23] Cupressacea trees refers to Cypress, it has 30 genera and 133 varieties.[24] It includes the following trees: Fitzroya, Pilgerodendron spp, Arbovitae spp, Austrocedrus, Cupressus spp, Callitris, Widdringtonian spp,Tetraclinis, Thujopsis, Chamaecyparis spp, Calocedrus, Juniperus spp, Athrotaxis, Cryptomeria, Cunninghamia, Sequoiadendrum, Sequoia, Metasequoia, Taxodium.
Essential oils with antiviral or antiseptic or immunomodulatory properties according to Schnaubelt, PhD are:[25]
· Cinnamon (Cinnamomum ceylanicum) – antiseptic. From a Traditional Chinese Medicine (TCM) perspective is warms Kidney yang (bark) and regulates the coronary arteries. Rou gui and Gui zhi are the Pin Yin for cinnamon in Chinese medicine.
· Clove (Eugenia caryophyllata) – antiseptic, “broad spectrum of action against bacteria; antiviral, strengthening.” (sic)
· Eucalyptus radiata – expectorant, antiviral. In TCM terms it strengthens Lung qi, opens the chest and transforms phlegm.
· Eucalyptus globulus and polybractea – expectorant. From a TCM perspective it tonifies Lung-Tai Yin Qi, regulates qi in the chest, and transforms phlegm.
· Frankincense (Boswellia carteri) – anti-asthmatic, strengthens the immune system. For Chinese medicine savvy readers Frankincense expands the chest and boost Wei-qi or Defensive qi.
· Hyssop (Hyssopus officinalis var decumbens) – strong antiviral effects and antiasthmatic. In TCM terms hyssop tonifies Lung-Tai Yin Qi and Wei-Qi therefore it treats shortness of breath, fatigue, and boost immune system.
· Laurel (Laurus nobilis) – is anti-infective (sic), it enhances the qualities of the other antiviral and antibacterial oils. In TCM, it is said that laurel moves qi and transforms phlegm.
· Myrrh (Commiphora molmol) – antiviral, anti-inflammatory (sic). TCM view on myrrh is that it strengthens the Spleen-Tai Yin meridian and drains dampness.
· Palmarosa (Cymbopogon martini) – effective against bacterial and viral illnesses of throat and lungs (sic). In Chinese medicine parlance it nourishes Yin and clears heat.
· Ravensare (Ravensare aromatica) – expectorant and antiviral (sic).
· Tea tree (Melaleuca alternifolia) – anti-infective agent with very broad spectrum of action (sic). It tonifies Lung qi and Wei-Qi therefore boosting the immune system functions and treating fatigue, or lethargy.
· Vetiver (Vetiveria zizanoides) – strengthens a weakened immune system. In TCM words, vetiver nourishes Yin and clears heat.
Note: previous essential oils information are direct quotes from Schnaubelt, PhD.
An excellent way of prevention is diffusing essential oil of Eucalyptus radiata, E. globulus, E. citriodora, Laurel, Tea tree, Hyssop, and Palmarosa.[26] A synergy of Eucalyptus spp, Tea tree, Laurel, Hyssop, and Palmarosa with Jojoba oil as a carrier and applied to acupuncture points Lung 1, Lung 5, and Lung 9 (See Diag 1, Diag 2 and Diag 3).
You can make your own synergy. You need the essential oils previously mentioned (7 in total), a 10 ml bottle and jojoba oil. The synergy’s dilution would be 10%. The ratio depends on how you want to do the blend but keep in mind that 1 ml is approximately 20 drops hence 10 ml bottle fits 200 drops and a 10% dilution yields a total of 20 drops. These 20 drops must be divided between Eucalyptus spp, Laurel, Tea tree, Palmarosa, and Hyssop. In theory, you can pour 2 to 3 drops of each essential oil.
Where you can obtain your essential oils? I get my oils from one of these 3 sources: Ananda Apothecary in Colorado, Enfleurage 237 West 13th Street New York, NY, and New York Institute of Aromatherapy in New York City at 530 E 13th Street, New York, NY 10009. Another good source of essential oils is Floracopeia. All are reliable sources who are committed to quality.
Diag 1 Lung 1
Diag 2 Lung 5 on elbow’s crease lateral to bicep tendon.
Diag 3 Lung 9
Supplements and The Immune System
Supplements can assist regulating, harmonizing, and boosting the immune system. My favorite combination is taking a multivitamin and mineral, adding an extra dose of 25 mg of zinc, selenium, and manganese while adding 1,500 mg of L-Carnitine. L-Carnitine is converted to L-Acetylcarnitine[27],[28],[29] which has immunomodulator, sedative, and analgesic effects. It regulates dopamine, serotonin, and GABA and has an affinity for the hippocampus and hypothalamus. Zinc, selenium, and manganese are the minerals needed to produce super oxidase dismutase and glutathione peroxidase, two antioxidants produced by the human; L-Glutamine[30], an amino acid, is involved in the production of glutathione peroxidase as well.
When zinc ions[31] enter in contact with other substances such as hinokitiol, Pyrrolidine DioThioCarbamate (PDTC),[32] and zinc pyrithione (PT) it exerts a dynamic response which promotes antioxidant, anticancer, and antiviral response.
DPTC[33] is a metal chelating agent that passes through the blood brain barrier and stimulates astrocytes, regulates production of glutathione, increases copper at a cellular level, and regulates nitric oxide synthetase. DPTC targets the hippocampus as well. DPTC has been shown to reduce effects of Alzheimer and stop viral replication of SARS-CoV. PT is zinc pyrithhione and has been noticed that in combination with zinc2+, hinokitiol, and PDTC it inhibits replication of SARS-CoV. It can be assumed that a regime involving vitamin/mineral supplementation, a good diet and hygiene, plenty of rest, and use of essential oils can be our best allies in staying healthy.
Nature’s Sunshine® offers an ample selection on supplements to support lung functions, regulate the immune system and fight viruses. My recommendation as a prophylactic measure is ALJ® and Enviro-Detox®. ALJ® enhances lung functions, cleanses the lung, and aids with allergies while Enviro-Detox® has antiviral properties.
Precautionary Approaches
Wash your hands thoroughly. Hand washing dislodges any bacteria, virus or any other pathogen from our hands. If you use Lysol or Clorox wipes you can add ethanol to them. Ethanol and HCL have shown strong antiviral activity. Avoid shaking hands, cover your mouth when sneezing. Stay home if you are sick. Drink ginger tea[34], studies show that ginger tea has anti-inflammatory properties and reduces inflammation markers including Nuclear Factor. Fresh ginger enhances catalase, superoxidase dismutase, and glutathione peroxidase.[35] Ginger treats even common cold.[36] Last, always gargle.
Biography:
Emmanuel Arroyo is a Licensed Acupuncturist in the State of NY, Certified in Iridology and Aromatherapy. Has a Master degree in Oriental Medicine and is Member of NCCAOM and ASNY.
If you are interested in having an essential oil synergy with antiviral and antibacterial properties or need a immune booster acupuncture treatment you can reach me at:
[1] Division of Disease Surveillance. Maine Center for Disease Control & Prevention. Accessed 28 January 2020. https://www.maine.gov/dhhs/mecdc/infectious-disease/epi/airborne/coronavirus.shtml
[2] Shiel, William C, MD, FACP, FACR. Medical Definition of Positive-strand RNA virus. Accessed 28 January 2020. https://www.medicinenet.com/script/main/art.asp?articlekey=22952
[3] Fehr, Anthony R, Perlman, Stanley. Coronaviruses: An Overview of Their Replication and Pathogenesis. Methods Mol Biol 2015; 1282:1-23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369385/
[4] Karlis, Nicole. Why COVID-19 is more insidious than other coronaviruses. Salon. February 28, 2020 12:35 AM (UTC) Accessed March 3, 2020. https://www.salon.com/2020/02/27/why-covid-19-is-more-insidious-than-other-coronaviruses/
[5] Thomas, Gary. Furin At The Cutting Edge: From Protein Traffic to Embryogenisis And Disease. Nat Rev Mol Cell Biol.2002 Oct; 3(10):753-766.
[6] Centers for Disease Control and Prevention. Accessed 28 January 2010. https://www.cdc.gov/coronavirus/types.html
[7] Coronavirus. Wikipedia. Accessed 28 January 2020. https://en.wikipedia.org/wiki/Coronavirus
[8] Interfero de Cuba Cura Coronavirus. 2 March 2020, accessed March 3, 2020. http://espanol.almayadeen.net/news/politics/1383512/interferón-de-cuba-cura-coronavirus?fbclid=IwAR2jTX-e17__mC4OAoULX4cxjKipG6xFN4jytWKU-YHDhCHUs3RCYB3Jq_I
[12] Virus and Bacteria that Clorox kills http://www.apex-reps.com/assets/site/uploads/cIoZUYBLIG.pdf
[13] Lin Lin, De-ping He, Yun Han, Ju-yin Xu, Zhi-xiu Lin. Treating Severe Acute Respiratory Sydrome with Integrated Chinese Medicine and Western Medicine – A Report on 103 Hospitalised Cases at the Second Affiliated Hospital of Guangzhou Universit of Chinese Medicine, China. Journal of Chinese Medicine Number 72 June 2003.
[14] Harvard Health Publishing. Harvard Medical School. Coronavirus Resource Center. Accessed March 3, 2020. https://www.health.harvard.edu/diseases-and-conditions/coronavirus-resource-center
[15] https://www.health.govt.nz/our-work/diseases-and-conditions/novel-coronavirus-2019-ncov accessed 29 January 2020
[16] Centers for Disease Control and Prevention. Accessed 28 January 2020. https://www.cdc.gov/coronavirus/2019-ncov/about/symptoms.html
[17] World health Organization. Accessed 28 January 2020. https://www.who.int/ith/2020-24-01-outbreak-of-Pneumonia-caused-by-new-coronavirus/en/
[18] Coronavirus Geometric Progression Suggests 100,000 in a Week. Accessed 29 January 2020. https://moneymaven.io/mishtalk/economics/coronavirus-geometric-progression-suggests-100-000-infections-in-a-week-jzcZTq6Je0GpmioumMXSyg
[19] Liang-Tzung Lin, Wen-Cha Hsu, Chun-Ching Lin. Antiviral Natural Products and Herbal Medicines. Journal of Traditional and Complementary Medicine. 4(1):24-35.
[20] Chen K John. Chinese Medical Herbology and Pharmacology. City of Industry: Art of Medicine Press, Inc. 2004.
[21] Chen K John. Chinese Medical Herbology and Pharmacology. City of Industry: Art of Medicine Press, Inc. 2004.
[22] Rajesh Kumar, Ganjhu et al. Herbal plants and plant preparations as remedial approach for viral diseases. Virus Dis. (October-December 2015) 26(4):225-236.
[23] Li L-H, Wu P, Lee J-Y, Li P-R, Hsieh W-Y, et al. (2014) Hinokitiol Induces DNA Damage and Autophagy followed by Cell Cycle Arrest and Senescence in Gefitinib-Resistant Lung Adenocarcinoma Cells. PLoS ONE 9(8): e104203. doi:10.1371/journal.pone.0104203
[24] Cupressacea. Britannica. Accessed 29 January 2020. https://www.britannica.com/plant/Cupressaceae
[25] Schnaubelt, PhD. Advanced Aromatherapy. Rochester: Healing Arts Press. 1995.
[26] Schnaubelt, PhD. Advanced Aromatherapy. Rochester: Healing Arts Press. 1995.
[27] Santina Chiechio, Pier Luigi Canonico, and Mariagrazia Grilli.L-Acetylcarnitine: A Mechanistically Distinctive and Potentially Rapid-Acting Antidepressant Drug. International Journal of Molecular Sciences. 2018, 19:11.
[28] Acetl-L-carnitine deficiency in patients with major depressive disorder. Carla Nasca, et al. PNAS. August 2018. Vol. 115, No. 34 pp 8627-8632.
[29] Null, Gary PhD. The Clinician’s Handbook of Natural Healing. New York: Kensington Publishing Corp. 1997.
[30] YU Jian-Chun, JIANG Zhu-Ming and LI De-Min. Glutamine: a precursor of glutathione and its effect
on liver. WJG, World Journal of Gastroenterology. 1999. April; 5(2):143-146.
[31] te Velthuis AJW, van den Worm SHE, Sims AC, Baric RS, Snijder EJ, et al. (2010) Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture. PLoS Pathog 6(11): e1001176. doi:10.1371/journal.ppat.1001176
[32] Liddell et al. Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes. Journal of Neuroinflammation (2016) 13:49
[33] Jin-dong Qin, Zhi-hong Cao, Xue-feng Li, Xiao-lin Kang, Yan Xue, Yue-ling Li, Dong Zhang, Xin-Yuan Liu, and Yong-zhi Xue. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-jB activation and CYP2E1 content of rats with immunological liver injury. Pharmaceutical Biology, 2014; 52(11):1460-1466.
[34] Chen, John K, and Chen, Tina T. Chinese Medical Herbology and Pharmacology. City of Industry: Art of Medicine Press. 2001.
[35] Nur Fatin Nabilah Mohd Sahardi and Suzana Makpol. Ginger (Zingiber officinale Roscoe) in the Prevention of Ageing and Degenerative Diseases: Review of Current Evidence-Based Complementary and Alternative Medicine. Vol 2019, Article ID 5054395, 13 pages.
Jengibre (Zingiber officinale) En Chino se le conoce como Sheng jiang (jengibre fresco) Gan jiang (seco/cristalizado) Pao jiang (reducido a cenizas) También baja el colesterol, los trigliceridos, previene enfermedades coronarias, protege las neuronas y las regenera. Anti-Cáncer, detiene hemorragias (mayormente relacionado con ciclo menstrual), es un relajante de bazos sanguineos por lo tanto baja la presión arterial, y trata dolores de cabeza. Referencias: Chen, John K, and Chen, Tina T. Chinese Medical Herbology and Pharmacology. City of Industry: Art of Medicine Press. 2001. Nuñez Meléndez, Esteban PhD. Plantas Medicinales de Puerto Rico. San Juan: Editorial de la Universidad de Puerto Rico. 1982. Nur Fatin Nabilah Mohd Sahardi and Suzana Makpol. Ginger (Zingiber officinale Roscoe) in the Prevention of Ageing and Degenerative Diseases: Review of Current Evidence-Based Complementary and Alternative Medicine. Vol 2019, Article ID 5054395, 13 pages. #acupuntura #medicinachina #medicinanatural #salud #newyork #plantasmedicinales #hierbas #jengibre #zingiberofficinale #diabetes #corazon #alzheimer #parkinson (at New York, New York) https://www.instagram.com/p/B8-ZMVLHHkH/?igshid=1ad8bhr20sucg
Jazmín de España (Jasminum grandiflorum) Referencias: Nuñez Melendez, Esteban PhD. Plantas Medicinales de Puerto Rico. San Juan: Editorial Universidad de Puerto Rico. 1982. Gupta, Rajesh K, Reddy, Pooja S. Antinociceptive and anticonvulsant activities of hydroalcoholic extract of Jasminum grandiflorum (jasmine) leaves in experimental animals. Pharmacognosy Research 5(4):286-290. HiraparaH, GhoriV,AnovadiyaA, BaxiS, TripathiC. Effects of ethanolic Extract of Jasminum grandiflorumLinn.Flowers on Wound Healing in Diabetic WistarAlbino Rats.Avicenna J Phytomed, 2017; 7 (5): 401-408. #acupuntura #medicinachina #medicinanatural #salud #newyork #plantasmedicinales #hierbas #puertorico #jasminumgrandiflorum [email protected] Www.arroyosacupuncture.com (at New York, New York) https://www.instagram.com/p/B8zmkuFn1uS/?igshid=1k50zcgwmpojg
Higuerillo Oloroso (Piper Marginatum) Referencias: Nuñez Melendez, Esteban PhD. Plantas Medicinales de Puerto Rico. San Juan: La Editorial, Universidad de Puerto Rico. 1982. Gamboa, Fredy et al. Antimicrobial Activity of Piper Marginatum Jaq and Ilex guayusa Loes on Microorganisms Associated with Periodontal Disease. International Journal of Microbiology. Vol 201. Article ID 4147383. #acupuntura #medicinachina #medicinanatural #salud #newyork #plantasmedicinales #hierbas #higuerillooloroso #pipermarginatum (at New York) https://www.instagram.com/p/B8fO51rHoiN/?igshid=7x5z013uj42d
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